Values CatLog read from this paper

Dual functional roles of ATP in the human mitochondrial malic enzyme

PMID 15182181doi:10.1021/bi049600rOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 10 records (15 values) from this paper: human mitochondrial NAD(P)+-dependent malic enzyme from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 5 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.1.1.38

Records read from this paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsOpen record
human mitochondrial NAD(P)+-dependent malic enzymeHomo sapiensL-malate261.419 calc.pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme, L-malate
human mitochondrial NAD(P)+-dependent malic enzymeHomo sapiensNAD+—0.13—pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme, NAD+
human mitochondrial NAD(P)+-dependent malic enzymevariant R197AHomo sapiensL-malate491.241 calc.pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R197A, L-malate
human mitochondrial NAD(P)+-dependent malic enzymevariant R197AHomo sapiensNAD+—0.13—pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R197A, NAD+
human mitochondrial NAD(P)+-dependent malic enzymevariant R197EHomo sapiensL-malate522.224 calc.pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R197E, L-malate
human mitochondrial NAD(P)+-dependent malic enzymevariant R197EHomo sapiensNAD+—0.179—pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R197E, NAD+
human mitochondrial NAD(P)+-dependent malic enzymevariant R542AHomo sapiensL-malate521.731 calc.pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R542A, L-malate
human mitochondrial NAD(P)+-dependent malic enzymevariant R542AHomo sapiensNAD+—0.243—pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R542A, NAD+
human mitochondrial NAD(P)+-dependent malic enzymevariant R542EHomo sapiensL-malate111.110 calc.pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R542E, L-malate
human mitochondrial NAD(P)+-dependent malic enzymevariant R542EHomo sapiensNAD+—0.204—pH 7.4, 30 °COpen record: human mitochondrial NAD(P)+-dependent malic enzyme variant R542E, NAD+