Values CatLog read from this paper
Optimization of a high throughput screening platform to identify inhibitors of asymmetric diadenosine polyphosphatases
PMID 39521360doi:10.1016/j.ab.2024.115713Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (17 values) from this paper: NudC (Orf257), Nudt1 (hMTH1), Nudt12 and 3 more from Homo sapiens, Escherichia coli, Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 3.6.1.10, EC 3.6.1.17, EC 3.6.1.22, EC 3.6.1.52, EC 3.6.1.56, EC 3.6.1.59, EC 3.6.1.61, EC 3.6.1.62, EC 3.6.1.69
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| NudC (Orf257) | Escherichia coli | P1,P5-di(adenosine-5') pentaphosphate | 0.014 | 0.015 | 0.96 | pH 8, 23 °C | Open record: NudC (Orf257), P1,P5-di(adenosine-5') pentaphosphate |
| Nudt1 (hMTH1) | Homo sapiens | P1,P5-di(adenosine-5') pentaphosphate | — | 0.026 | 0.0058 | pH 8, 23 °C | Open record: Nudt1 (hMTH1), P1,P5-di(adenosine-5') pentaphosphate |
| Nudt12 | Homo sapiens | P1,P5-di(adenosine-5') pentaphosphate | 0.011 | 0.39 | 0.029 | pH 8, 23 °C | Open record: Nudt12, P1,P5-di(adenosine-5') pentaphosphate |
| Nudt2 (hHAPH1) | Homo sapiens | P1,P5-di(adenosine-5') pentaphosphate | 0.47 | 0.033 | 14 | pH 8, 23 °C | Open record: Nudt2 (hHAPH1), P1,P5-di(adenosine-5') pentaphosphate |
| Nudt3 (DIPP) | Homo sapiens | P1,P5-di(adenosine-5') pentaphosphate | 4 × 10⁻⁴ | 0.024 | 0.016 | pH 8, 23 °C | Open record: Nudt3 (DIPP), P1,P5-di(adenosine-5') pentaphosphate |
| Rv2985 nudix Ap_nA hydrolase | Mycobacterium tuberculosis | P1,P5-di(adenosine-5') pentaphosphate | 0.48 | 0.053 | 9 | pH 8, 23 °C | Open record: Rv2985 nudix Ap_nA hydrolase, P1,P5-di(adenosine-5') pentaphosphate |