CatLogenzyme kinetics catalog

EC 3.6.1.17: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

HydrolasesOpen in Browse

CatLog read 29 records for EC 3.6.1.17 from 4 papers, for 4 organisms. Names in these papers: diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase), CT771 (Ap4A hydrolase, nudH), PrpA, Nudt2 (hHAPH1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 39 records for EC 3.6.1.17 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.17 in Browse.

Papers

PaperOrganismsRecords
Analysis of the catalytic and binding residues of the diadenosine tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans by site-directed mutagenesisCaenorhabditis elegans17
Chlamydia trachomatis CT771 (nudH) is an asymmetric Ap4A hydrolaseChlamydia trachomatis6
Enzymatic characteristics of an ApaH-like phosphatase, PrpA, and a diadenosine tetraphosphate hydrolase, ApaH, from Myxococcus xanthusMyxococcus xanthus5
Optimization of a high throughput screening platform to identify inhibitors of asymmetric diadenosine polyphosphatasesHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate1.5 mM MnCl21.60.00728220pH 7.5PMID 24354275Open
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate3.0 mM MnCl21.510.00935160pH 7.5PMID 24354275Open
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate5.0 mM MnCl20.680.00498140pH 7.5PMID 24354275Open
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate1.5 mM MgCl21.780.4074.4pH 7.5PMID 24354275Open
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate3.0 mM MgCl22.240.3266.9pH 7.5PMID 24354275Open
CT771 (Ap4A hydrolase, nudH)Chlamydia trachomatisdiadenosine 5',5'''-P1,P4-tetraphosphate5.0 mM MgCl23.250.3339.8pH 7.5PMID 24354275Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)Caenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate230.00882.6 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant E103QCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate0.750.0058130 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant E52QCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate0.00520.00530.98 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant E56QCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate2.4 × 10⁻⁴0.00790.030 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant H31ACaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate120.073160 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant H31VCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate140.11130 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant H38GCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate310.00585.3 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant H38KCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate310.00417.6 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant K36MCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate2.10.013160 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant K79MCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate0.160.01511 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant K81MCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate300.021.5 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant K83MCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate0.60.144.3 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant Y121ACaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate140.075190 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant Y27ACaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate260.0112.4 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant Y27DCaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate290.0161.8 × 10³ calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant Y76ACaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate20.05934 calc.PMID 12475970Open
diadenosine tetraphosphate pyrophosphohydrolase (Ap4A hydrolase)variant Y76A/Y121ACaenorhabditis elegansdiadenosine 5',5'''-P1,P4-tetraphosphate1.10.03333 calc.PMID 12475970Open
Nudt2 (hHAPH1)Homo sapiensP1,P5-di(adenosine-5') pentaphosphate0.470.03314pH 8, 23 °CPMID 39521360Open
PrpAMyxococcus xanthusadenosine 5'-triphosphate0.0030.0560.065PMID 25107648Open
PrpAMyxococcus xanthusdiadenosine pentaphosphate0.0350.190.18pH 8, 50 °CPMID 25107648Open
PrpAMyxococcus xanthusdiadenosine tetraphosphate0.0550.140.4pH 8, 50 °CPMID 25107648Open
PrpAMyxococcus xanthusp-nitrophenyl phosphate27.117.53.63pH 8, 50 °CPMID 25107648Open
PrpAMyxococcus xanthusRRLIEDAEpYAARG0.0170.210.085pH 8PMID 25107648Open