CatLogenzyme kinetics catalog

EC 3.6.1.62: 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase

HydrolasesOpen in Browse

CatLog read 39 records for EC 3.6.1.62 from 6 papers, for 2 organisms. Names in these papers: DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase), NUDT16, DIPP (diphosphoinositol polyphosphate phosphohydrolase) and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 3.6.1.62 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.62 in Browse.

Papers

PaperOrganismsRecords
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1Homo sapiens21
NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrestHomo sapiens7
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine MonophosphateHomo sapiens5
The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping…Homo sapiens3
NUDIX hydrolases with inorganic polyphosphate exo- and endopolyphosphatase activities in the glycosome, cytosol and nucleus of Trypanosoma bruceiTrypanosoma brucei2
Optimization of a high throughput screening platform to identify inhibitors of asymmetric diadenosine polyphosphatasesHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
DIPP (diphosphoinositol polyphosphate phosphohydrolase)Homo sapiensdiadenosine 5',5'''-P1,P5-pentaphosphate0.420.007755pH 7.6, 37 °CPMID 10419486Open
DIPP (diphosphoinositol polyphosphate phosphohydrolase)Homo sapiensdiadenosine 5',5'''-P1,P6-hexaphosphate0.50.005985pH 7.6, 37 °CPMID 10419486Open
DIPP (diphosphoinositol polyphosphate phosphohydrolase)Homo sapiensdiphosphoinositol pentakisphosphate0.24.2 × 10⁻⁶4.74 × 10⁴pH 7.2PMID 10419486Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate0.237—1.5 × 10³pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate0.165—1.79 × 10³pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens2-diphospho-myo-inositol 1,3,4,5,6-pentakisphosphate0.042—460pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens4-diphospho-1D-myo-inositol 1,2,3,5,6-pentakisphosphate0.029—210pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate0.081—650pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)Homo sapiens5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate0.095—380pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42AHomo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate——520pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42AHomo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate——680pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42AHomo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate——150pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42A/R45AHomo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate——110pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42A/R45AHomo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate——200pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant H42A/R45AHomo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate——80pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant K18AHomo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate——50pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant K18AHomo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate——70pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant K18AHomo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate——40pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R41AHomo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate——590pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R41AHomo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate——690pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R41AHomo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate——230pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R45AHomo sapiens1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate——540pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R45AHomo sapiens1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate——860pH 7.2PMID 33475202Open
DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1)variant R45AHomo sapiens5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate——300pH 7.2PMID 33475202Open
Nudix hydrolase TbNH4 (TbDcp2)Trypanosoma bruceiinorganic polyphosphate (polyP60)—0.0822340pH 8, 37 °CPMID 31043451Open
Nudix hydrolase TbNH4 (TbDcp2)Trypanosoma bruceiinorganic polyphosphate (polyP700)—0.1494110pH 8, 37 °CPMID 31043451Open
NUDT16Homo sapiensadenosine 5'-diphosphate0.09590.1850.52pH 7.5, 37 °CPMID 26121039Open
NUDT16Homo sapiensinosine 5'-triphosphate0.012730.008231.55pH 7.5, 37 °CPMID 26121039Open
NUDT16Homo sapiensxanthosine 5'-diphosphate0.006130.006220.99pH 7.5, 37 °CPMID 26121039Open
NUDT16variant A22VHomo sapiensinosine 5'-triphosphate0.006570.012820.513pH 7.5, 37 °CPMID 26121039Open
NUDT16variant A22VHomo sapiensxanthosine 5'-diphosphate0.005150.00970.53pH 7.5, 37 °CPMID 26121039Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiens2'-deoxyguanosine 5'-diphosphate0.00823.19 × 10⁻⁴25.7pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiens2'-deoxyinosine 5'-diphosphate0.01618.8 × 10⁻⁵183pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiens2'-deoxyinosine 5'-triphosphate0.05330.02412.21pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiensguanosine 5'-diphosphate0.008633.3 × 10⁻⁴26.1pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiensinosine 5'-diphosphate0.015526.2 × 10⁻⁵251pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiensinosine 5'-triphosphate0.0510.02212.31pH 7.5, 37 °CPMID 20385596Open
NUDT16 (nucleoside diphosphate linked moiety X-type motif 16; (deoxy)inosine diphosphatase)Homo sapiensxanthosine 5'-diphosphate0.04330.01572.76pH 7.5, 37 °CPMID 20385596Open
Nudt3 (DIPP)Homo sapiensP1,P5-di(adenosine-5') pentaphosphate4 × 10⁻⁴0.0240.016pH 8, 23 °CPMID 39521360Open