Values CatLog read from this paper
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum
PMID 22359643doi:10.1371/journal.pone.0031938Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 30 records (90 values) from this paper: M1 alanyl aminopeptidase (PfM1AAP), M17 leucine aminopeptidase (PfM17LAP) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | 3-(2-naphthyl)alanine 7-amido-4-carbamoylmethylcoumarin | 0.884 | 0.3166 | 2.792 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), 3-(2-naphthyl)alanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | 3-nitrophenylalanine 7-amido-4-carbamoylmethylcoumarin | 0.141 | 0.1317 | 1.072 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), 3-nitrophenylalanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | alanine 7-amido-4-carbamoylmethylcoumarin | 1.054 | 0.2406 | 4.379 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), alanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | allylglycine 7-amido-4-carbamoylmethylcoumarin | 1.52 | 0.2667 | 5.7 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), allylglycine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | arginine 7-amido-4-carbamoylmethylcoumarin | 0.876 | 0.2143 | 4.086 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), arginine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | cyclohexylalanine 7-amido-4-carbamoylmethylcoumarin | 1.358 | 0.2698 | 5.034 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), cyclohexylalanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | homoarginine 7-amido-4-carbamoylmethylcoumarin | 1.144 | 0.1243 | 9.206 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), homoarginine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | homocyclohexylalanine 7-amido-4-carbamoylmethylcoumarin | 1.592 | 0.0963 | 16.53 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), homocyclohexylalanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | homoleucine 7-amido-4-carbamoylmethylcoumarin | 1.859 | 0.2108 | 8.819 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), homoleucine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | homophenylalanine 7-amido-4-carbamoylmethylcoumarin | 0.978 | 0.0608 | 16.10 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), homophenylalanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | Igl-ACC | 0.492 | 0.0847 | 5.811 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), Igl-ACC |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | leucine 7-amido-4-carbamoylmethylcoumarin | 0.868 | 0.1409 | 6.159 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), leucine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | methionine 7-amido-4-carbamoylmethylcoumarin | 0.887 | 0.1382 | 6.42 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), methionine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | norleucine 7-amido-4-carbamoylmethylcoumarin | 1.399 | 0.1101 | 12.71 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), norleucine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | norvaline 7-amido-4-carbamoylmethylcoumarin | 2.786 | 0.2671 | 10.43 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), norvaline 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | phenylalanine 7-amido-4-carbamoylmethylcoumarin | 0.422 | 0.218 | 1.937 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), phenylalanine 7-amido-4-carbamoylmethylcoumarin |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | styryl-Ala-ACC | 0.937 | 0.1927 | 4.864 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), styryl-Ala-ACC |
| M1 alanyl aminopeptidase (PfM1AAP) | Plasmodium falciparum | tryptophan 7-amido-4-carbamoylmethylcoumarin | 0.444 | 0.1444 | 3.071 | pH 7.5, 37 °C | Open record: M1 alanyl aminopeptidase (PfM1AAP), tryptophan 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | allylglycine 7-amido-4-carbamoylmethylcoumarin | 4.79 × 10⁻⁴ | 0.01135 | 0.0423 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), allylglycine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | cyclohexylalanine 7-amido-4-carbamoylmethylcoumarin | 8.39 × 10⁻⁴ | 0.007777 | 0.1079 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), cyclohexylalanine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | homocyclohexylalanine 7-amido-4-carbamoylmethylcoumarin | 2.11 × 10⁻⁴ | 4.37 × 10⁻⁴ | 0.4832 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), homocyclohexylalanine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | homoleucine 7-amido-4-carbamoylmethylcoumarin | 7.17 × 10⁻⁴ | 0.004059 | 0.1766 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), homoleucine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | homophenylalanine 7-amido-4-carbamoylmethylcoumarin | 2.77 × 10⁻⁴ | 5.95 × 10⁻⁴ | 0.4663 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), homophenylalanine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | Igl-ACC | 1.53 × 10⁻⁴ | 3.42 × 10⁻⁴ | 0.4489 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), Igl-ACC |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | leucine 7-amido-4-carbamoylmethylcoumarin | 0.002622 | 0.03032 | 0.0825 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), leucine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | methionine 7-amido-4-carbamoylmethylcoumarin | 1.17 × 10⁻⁴ | 0.00344 | 0.0341 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), methionine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | norleucine 7-amido-4-carbamoylmethylcoumarin | 6.18 × 10⁻⁴ | 0.003293 | 0.1878 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), norleucine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | norvaline 7-amido-4-carbamoylmethylcoumarin | 9.23 × 10⁻⁴ | 0.008487 | 0.1088 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), norvaline 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | phenylalanine 7-amido-4-carbamoylmethylcoumarin | 0.001668 | 0.009267 | 0.18 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), phenylalanine 7-amido-4-carbamoylmethylcoumarin |
| M17 leucine aminopeptidase (PfM17LAP) | Plasmodium falciparum | tryptophan 7-amido-4-carbamoylmethylcoumarin | 0.003194 | 0.02299 | 0.139 | pH 8, 37 °C | Open record: M17 leucine aminopeptidase (PfM17LAP), tryptophan 7-amido-4-carbamoylmethylcoumarin |