CatLogenzyme kinetics catalog

Values CatLog read from this paper

Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding

PMID 17973628doi:10.1042/bj20071033Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 20 records (20 values) from this paper: tryptophan hydroxylase 2 (TPH2) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.14.16.4

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
tryptophan hydroxylase 2 (TPH2)Homo sapiensL-tryptophan—0.0449—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)Homo sapiensL-tryptophanin buffer only (non-phosphorylated TPH2)—0.0545—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)Homo sapienstetrahydrobiopterin—0.0423—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)Homo sapienstetrahydrobiopterinin buffer only (non-phosphorylated TPH2)—0.0351—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104AHomo sapiensL-tryptophan—0.0776—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104AHomo sapiensL-tryptophanin buffer only (non-phosphorylated TPH2)—0.0618—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104AHomo sapienstetrahydrobiopterin—0.175—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104AHomo sapienstetrahydrobiopterinin buffer only (non-phosphorylated TPH2)—0.1514—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104EHomo sapiensL-tryptophan—0.0786—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104EHomo sapiensL-tryptophanin buffer only (non-phosphorylated TPH2)—0.0677—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104EHomo sapienstetrahydrobiopterin—0.1628—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S104EHomo sapienstetrahydrobiopterinin buffer only (non-phosphorylated TPH2)—0.1488—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19AHomo sapiensL-tryptophan—0.1042—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19AHomo sapiensL-tryptophanin buffer only (non-phosphorylated TPH2)—0.0987—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19AHomo sapienstetrahydrobiopterin—0.0721—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19AHomo sapienstetrahydrobiopterinin buffer only (non-phosphorylated TPH2)—0.0797—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19EHomo sapiensL-tryptophan—0.0354—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19EHomo sapiensL-tryptophanin buffer only (non-phosphorylated TPH2)—0.0402—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19EHomo sapienstetrahydrobiopterin—0.0433—pH 7, 30 °COpen
tryptophan hydroxylase 2 (TPH2)variant S19EHomo sapienstetrahydrobiopterinin buffer only (non-phosphorylated TPH2)—0.0577—pH 7, 30 °COpen