Values CatLog read from this paper
Site-directed mutation of conserved cysteine residues does not inactivate the Streptococcus pyogenes hyaluronan synthase
PMID 11805074doi:10.1093/glycob/11.12.1017Open in Browse
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CatLog read 18 records (18 values) from this paper: hyaluronan synthase (spHAS) from Streptococcus pyogenes.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| hyaluronan synthase (spHAS) | Streptococcus pyogenes | UDP-GlcUA | — | 0.0504 | — | Open record: hyaluronan synthase (spHAS), UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C124A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0373 | — | Open record: hyaluronan synthase (spHAS) variant C124A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C124A/C261A/C280A/C366A/C402A | Streptococcus pyogenes | UDP-GlcUA | — | 0.101 | — | Open record: hyaluronan synthase (spHAS) variant C124A/C261A/C280A/C366A/C402A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C124A/C366A/C402A | Streptococcus pyogenes | UDP-GlcUA | — | 0.13 | — | Open record: hyaluronan synthase (spHAS) variant C124A/C366A/C402A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C124A/C402A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0395 | — | Open record: hyaluronan synthase (spHAS) variant C124A/C402A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C124S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0327 | — | Open record: hyaluronan synthase (spHAS) variant C124S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C225A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0622 | — | Open record: hyaluronan synthase (spHAS) variant C225A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C225S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0427 | — | Open record: hyaluronan synthase (spHAS) variant C225S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C261A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0426 | — | Open record: hyaluronan synthase (spHAS) variant C261A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C261A/C280A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0548 | — | Open record: hyaluronan synthase (spHAS) variant C261A/C280A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C261S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0456 | — | Open record: hyaluronan synthase (spHAS) variant C261S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C280A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0338 | — | Open record: hyaluronan synthase (spHAS) variant C280A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C280S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0294 | — | Open record: hyaluronan synthase (spHAS) variant C280S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C366A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0568 | — | Open record: hyaluronan synthase (spHAS) variant C366A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C366S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0341 | — | Open record: hyaluronan synthase (spHAS) variant C366S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C402A | Streptococcus pyogenes | UDP-GlcUA | — | 0.0438 | — | Open record: hyaluronan synthase (spHAS) variant C402A, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant C402S | Streptococcus pyogenes | UDP-GlcUA | — | 0.0444 | — | Open record: hyaluronan synthase (spHAS) variant C402S, UDP-GlcUA | |
| hyaluronan synthase (spHAS)variant Cys-null (C124A/C225A/C261A/C280A/C366A/C402A) | Streptococcus pyogenes | UDP-GlcUA | — | 0.153 | — | Open record: hyaluronan synthase (spHAS) variant Cys-null (C124A/C225A/C261A/C280A/C366A/C402A), UDP-GlcUA |