CatLogenzyme kinetics catalog

Values CatLog read from this paper

Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis

PMID 38944687doi:10.1111/febs.17202Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 15 records (43 values) from this paper: NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase), NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.6.1.9, EC 3.6.1.58

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensdeoxyguanosine 5'-triphosphate0.5820.022326.29pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensdimethylallyl pyrophosphate0.940.15936.47pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensfarnesyl pyrophosphate0.10.07631.35pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensgeranyl pyrophosphate100 mM tris acetate pH 8.0; 0.01% Tween 20; 25 nM enzyme0.720.018739.86pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensgeranyl pyrophosphate0.1 M tris acetate pH 8.0; without Tween 20; 50 nM NUDT150.15080.03244.661pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensgeranylgeranyl pyrophosphate0.10.16330.87pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)Homo sapiensisopentenyl pyrophosphate0.490.06368.33pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)variant H49AHomo sapiensdeoxyguanosine 5'-triphosphate0.3670.3780.9942pH 8, 22 °COpen
NUDT15 (NUDIX hydrolase 15, nucleotide triphosphate diphosphatase)variant H49AHomo sapiensgeranyl pyrophosphate0.0053——pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensdimethylallyl pyrophosphate0.940.009899.7pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensfarnesyl pyrophosphate0.520.018827.5pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensgeranyl pyrophosphate0.780.0037214.3pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensgeranylgeranyl pyrophosphate0.150.01798.5pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensisopentenyl pyrophosphate0.870.012472.1pH 8, 22 °COpen
NUDT18 (NUDIX hydrolase 18, 8-oxo-dGDP phosphatase)Homo sapiensmevalonate pyrophosphate0.550.026820.4pH 8, 22 °COpen