Values CatLog read from this paper

Aspartate 458 of human glutathione synthetase is important for cooperativity and active site structure

PMID 21771585doi:10.1016/j.bbrc.2011.06.166Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 12 records (12 values) from this paper: glutathione synthetase from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 6.3.2.3

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
glutathione synthetase	Homo sapiens	glycine	—	0.58	—	pH 8.2, 37 °C	Open record: glutathione synthetase, glycine
glutathione synthetase	Homo sapiens	γ-glutamyl-α-aminobutyrate	15.68	—	—	pH 8.2, 37 °C	Open record: glutathione synthetase, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458A	Homo sapiens	glycine	—	35	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458A, glycine
glutathione synthetasevariant D458A	Homo sapiens	γ-glutamyl-α-aminobutyratestandard assay: 20 mM GAB; 10 mM glycine; 10 mM ATP	1.6	—	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458A, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458A	Homo sapiens	γ-glutamyl-α-aminobutyrateother substrates saturating	—	0.25	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458A, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458N	Homo sapiens	glycine	—	16	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458N, glycine
glutathione synthetasevariant D458N	Homo sapiens	glycineenzyme re-assayed after storage; at peak activity	—	0.77	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458N, glycine
glutathione synthetasevariant D458N	Homo sapiens	γ-glutamyl-α-aminobutyratestandard assay: 20 mM GAB; 10 mM glycine; 10 mM ATP	2.31	—	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458N, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458N	Homo sapiens	γ-glutamyl-α-aminobutyrateother substrates saturating	—	0.12	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458N, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458R	Homo sapiens	glycine	—	51	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458R, glycine
glutathione synthetasevariant D458R	Homo sapiens	γ-glutamyl-α-aminobutyratestandard assay: 20 mM GAB; 10 mM glycine; 10 mM ATP	1.17	—	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458R, γ-glutamyl-α-aminobutyrate
glutathione synthetasevariant D458R	Homo sapiens	γ-glutamyl-α-aminobutyrateother substrates saturating	—	0.29	—	pH 8.2, 37 °C	Open record: glutathione synthetase variant D458R, γ-glutamyl-α-aminobutyrate