CatLogenzyme kinetics catalog

Values CatLog read from this paper

The β and γ subunits play distinct functional roles in the α2βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase

PMID 28139779doi:10.1038/srep41882Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 19 records (27 values) from this paper: NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimer, NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramer, NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimer from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 1.1.1.41

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 226.7——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 328.4——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 423.4——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramerHomo sapiensDL-isocitratestandard conditions: 33 mM Tris-acetate pH 7.4; 25 °C23.8——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramervariant K151A (γ subunit)Homo sapiensDL-isocitrateno regulators—21.90.501pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) α2βγ heterotetramervariant K151A (γ subunit)Homo sapiensDL-isocitratewith 1 mM citrate (CIT) and 1 mM ADP—17.60.607pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 214.6——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 315.8——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate50 mM MnCl2; varied DL-isocitrate; 25 °C; no regulators—13.41.08pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate50 mM MnCl2; varied DL-isocitrate; 25 °C; apparent Km—12.1—pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate50 mM MnCl2; varied DL-isocitrate; 25 °C; with 1 mM ADP—12.1—pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αβ heterodimerHomo sapiensDL-isocitrate50 mM MnCl2; varied DL-isocitrate; 25 °C; apparent Km—12.61.25pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 29.72——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 317.6——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitrate33 mM Tris-acetate pH 7.4; varied ICT (0-80 mM); Table 411.9——pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitratestandard conditions: 33 mM Tris-acetate pH 7.4; 25 °C—2.61—pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitratestandard conditions: 33 mM Tris-acetate pH 7.4; 25 °C—0.18296.7pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitratestandard conditions: 33 mM Tris-acetate pH 7.4; 25 °C—0.30938.5pH 7.4, 25 °COpen
NAD-dependent isocitrate dehydrogenase (NAD-IDH, IDH3) αγ heterodimerHomo sapiensDL-isocitratestandard conditions: 33 mM Tris-acetate pH 7.4; 25 °C14.30.3343.3pH 7.4, 25 °COpen