Values CatLog read from this paper
Substrate specificity analysis and inhibitor design of homoisocitrate dehydrogenase
PMID 17116397doi:10.1016/j.bmc.2006.11.008Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 25 records (75 values) from this paper: homoisocitrate dehydrogenase (ScHICDH), homoisocitrate dehydrogenase (DraHICDH) from Saccharomyces cerevisiae, Deinococcus radiodurans.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-(2-hydroxyethyl)malate | 25 | 0.59 | 42 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(2-hydroxyethyl)malate |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-(3-hydroxypropyl)malate | 29 | 0.51 | 57 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(3-hydroxypropyl)malate |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-(4-hydroxybutyl)malate | 28 | 0.47 | 60 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(4-hydroxybutyl)malate |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-(4-pentenyl)malic acid | 3 | 2.7 | 1.1 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(4-pentenyl)malic acid |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-allylmalic acid | 37 | 2.8 | 13 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-allylmalic acid |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | (2R,3S)-3-propylmalic acid | 53 | 0.78 | 68 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-propylmalic acid |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | 3-vinylmalate (compound 19) | 0.77 | 0.083 | 9.3 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), 3-vinylmalate (compound 19) |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | compound 10 (3-alkylmalate) | 19 | 3.6 | 5.3 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), compound 10 (3-alkylmalate) |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | compound 14 (3-alkylmalate) | 3.7 | 3.2 | 1.2 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), compound 14 (3-alkylmalate) |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | compound 3 (homoanalog of homoisocitrate) | 40 | 0.2 | 200 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), compound 3 (homoanalog of homoisocitrate) |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | compound 4 (homoanalog of homoisocitrate) | 40 | 0.14 | 290 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), compound 4 (homoanalog of homoisocitrate) |
| homoisocitrate dehydrogenase (DraHICDH) | Deinococcus radiodurans | ethylmalate (compound 11) | 43 | 1 | 43 | pH 7.8, 28 °C | Open record: homoisocitrate dehydrogenase (DraHICDH), ethylmalate (compound 11) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-(2-hydroxyethyl)malate | 0.78 | 2.1 | 0.37 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(2-hydroxyethyl)malate |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-(3-hydroxypropyl)malate | 4.8 | 0.58 | 8.3 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(3-hydroxypropyl)malate |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-(4-hydroxybutyl)malate | 2.1 | 0.44 | 4.8 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(4-hydroxybutyl)malate |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-(4-pentenyl)malic acid | 0.14 | 9.4 | 0.015 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(4-pentenyl)malic acid |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-allylmalic acid | 0.34 | 0.41 | 0.83 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-allylmalic acid |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-3-propylmalic acid | 0.7 | 0.29 | 2.4 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-propylmalic acid |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | (2R,3S)-homoisocitrate | 17 | 0.018 | 940 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-homoisocitrate |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | 3-vinylmalate (compound 19) | 0.5 | 3.4 | 0.15 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), 3-vinylmalate (compound 19) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | compound 10 (3-alkylmalate) | 0.32 | 5.7 | 0.056 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), compound 10 (3-alkylmalate) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | compound 14 (3-alkylmalate) | 0.11 | 7.2 | 0.015 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), compound 14 (3-alkylmalate) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | compound 3 (homoanalog of homoisocitrate) | 1.6 | 0.026 | 62 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), compound 3 (homoanalog of homoisocitrate) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | compound 4 (homoanalog of homoisocitrate) | 3.1 | 0.17 | 18 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), compound 4 (homoanalog of homoisocitrate) |
| homoisocitrate dehydrogenase (ScHICDH) | Saccharomyces cerevisiae | ethylmalate (compound 11) | 0.61 | 0.6 | 1 | pH 7.8, 36 °C | Open record: homoisocitrate dehydrogenase (ScHICDH), ethylmalate (compound 11) |