EC 1.1.1.115: ribose 1-dehydrogenase (NADP+)

OxidoreductasesOpen in Browse

CatLog read 35 records for EC 1.1.1.115 from 3 papers, for 3 organisms. Names in these papers: homoisocitrate dehydrogenase (ScHICDH), homoisocitrate dehydrogenase (DraHICDH), homoisocitrate dehydrogenase (Dra-HICDH), homoisocitrate dehydrogenase (HICDH).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 2 records for EC 1.1.1.115 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.115 in Browse.

Papers

Papers with records for EC 1.1.1.115
Paper	Organisms	Records
Substrate specificity analysis and inhibitor design of homoisocitrate dehydrogenase	Deinococcus radiodurans, Saccharomyces cerevisiae	25
Identification of a novel trifunctional homoisocitrate dehydrogenase and modulation of the broad substrate specificity through site-directed mutagenesis	Deinococcus radiodurans	8
Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of…	Thermus thermophilus	2

Records

Records for EC 1.1.1.115 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
homoisocitrate dehydrogenase (Dra-HICDH)	Deinococcus radiodurans	(2R,3S)-homoisocitrate	46.2	0.211	219	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH), (2R,3S)-homoisocitrate
homoisocitrate dehydrogenase (Dra-HICDH)	Deinococcus radiodurans	D,L-3-isopropylmalate	0.371	1.33	0.279	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH), D,L-3-isopropylmalate
homoisocitrate dehydrogenase (Dra-HICDH)	Deinococcus radiodurans	D,L-isocitrate	42.8	0.291	147	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH), D,L-isocitrate
homoisocitrate dehydrogenase (Dra-HICDH)	Deinococcus radiodurans	NAD+	30.3	0.193	157 calc.	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH), NAD+
homoisocitrate dehydrogenase (Dra-HICDH)variant R87T	Deinococcus radiodurans	(2R,3S)-homoisocitrate	27.8	1.5	18.5	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH) variant R87T, (2R,3S)-homoisocitrate
homoisocitrate dehydrogenase (Dra-HICDH)variant R87V	Deinococcus radiodurans	(2R,3S)-homoisocitrate	20.8	1	20.8	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH) variant R87V, (2R,3S)-homoisocitrate
homoisocitrate dehydrogenase (Dra-HICDH)ΔA80 (in-frame deletion of Ala80)	Deinococcus radiodurans	(2R,3S)-homoisocitrate	5.46	0.819	6.67	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH) ΔA80 (in-frame deletion of Ala80), (2R,3S)-homoisocitrate
homoisocitrate dehydrogenase (Dra-HICDH)ΔA80 (in-frame deletion of Ala80)	Deinococcus radiodurans	D,L-isocitrate	10.9	0.465	23.4	pH 7.8, 30 °C	PMID 16139794	Open record: homoisocitrate dehydrogenase (Dra-HICDH) ΔA80 (in-frame deletion of Ala80), D,L-isocitrate
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-(2-hydroxyethyl)malate	25	0.59	42	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(2-hydroxyethyl)malate
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-(3-hydroxypropyl)malate	29	0.51	57	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(3-hydroxypropyl)malate
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-(4-hydroxybutyl)malate	28	0.47	60	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(4-hydroxybutyl)malate
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-(4-pentenyl)malic acid	3	2.7	1.1	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-(4-pentenyl)malic acid
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-allylmalic acid	37	2.8	13	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-allylmalic acid
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	(2R,3S)-3-propylmalic acid	53	0.78	68	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), (2R,3S)-3-propylmalic acid
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	3-vinylmalate (compound 19)	0.77	0.083	9.3	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), 3-vinylmalate (compound 19)
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	compound 10 (3-alkylmalate)	19	3.6	5.3	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), compound 10 (3-alkylmalate)
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	compound 14 (3-alkylmalate)	3.7	3.2	1.2	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), compound 14 (3-alkylmalate)
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	compound 3 (homoanalog of homoisocitrate)	40	0.2	200	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), compound 3 (homoanalog of homoisocitrate)
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	compound 4 (homoanalog of homoisocitrate)	40	0.14	290	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), compound 4 (homoanalog of homoisocitrate)
homoisocitrate dehydrogenase (DraHICDH)	Deinococcus radiodurans	ethylmalate (compound 11)	43	1	43	pH 7.8, 28 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (DraHICDH), ethylmalate (compound 11)
homoisocitrate dehydrogenase (HICDH)	Thermus thermophilus	homoisocitrate	171	7.486	23	pH 8, 60 °C	PMID 12427751	Open record: homoisocitrate dehydrogenase (HICDH), homoisocitrate
homoisocitrate dehydrogenase (HICDH)	Thermus thermophilus	isocitrate	171	0.405	420	pH 8, 60 °C	PMID 12427751	Open record: homoisocitrate dehydrogenase (HICDH), isocitrate
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-(2-hydroxyethyl)malate	0.78	2.1	0.37	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(2-hydroxyethyl)malate
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-(3-hydroxypropyl)malate	4.8	0.58	8.3	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(3-hydroxypropyl)malate
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-(4-hydroxybutyl)malate	2.1	0.44	4.8	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(4-hydroxybutyl)malate
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-(4-pentenyl)malic acid	0.14	9.4	0.015	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-(4-pentenyl)malic acid
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-allylmalic acid	0.34	0.41	0.83	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-allylmalic acid
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-3-propylmalic acid	0.7	0.29	2.4	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-3-propylmalic acid
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	(2R,3S)-homoisocitrate	17	0.018	940	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), (2R,3S)-homoisocitrate
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	3-vinylmalate (compound 19)	0.5	3.4	0.15	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), 3-vinylmalate (compound 19)
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	compound 10 (3-alkylmalate)	0.32	5.7	0.056	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), compound 10 (3-alkylmalate)
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	compound 14 (3-alkylmalate)	0.11	7.2	0.015	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), compound 14 (3-alkylmalate)
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	compound 3 (homoanalog of homoisocitrate)	1.6	0.026	62	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), compound 3 (homoanalog of homoisocitrate)
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	compound 4 (homoanalog of homoisocitrate)	3.1	0.17	18	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), compound 4 (homoanalog of homoisocitrate)
homoisocitrate dehydrogenase (ScHICDH)	Saccharomyces cerevisiae	ethylmalate (compound 11)	0.61	0.6	1	pH 7.8, 36 °C	PMID 17116397	Open record: homoisocitrate dehydrogenase (ScHICDH), ethylmalate (compound 11)