Values CatLog read from this paper
A crucial active site network of titratable residues guides catalysis and NAD+ binding in human succinic semialdehyde dehydrogenase
PMID 39731543doi:10.1002/pro.70024Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 12 records (18 values) from this paper: succinic semialdehyde dehydrogenase (hSSADH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized)subinhibitory SSA (1-10 μM); NAD+ varied | — | 0.014 | — | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized)subinhibitory SSA (1-10 μM); full-range NAD+ | — | 0.036 | — | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized)inhibitory SSA (12-200 μM) | — | 0.032 | — | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized)full-range SSA and NAD+ | — | 0.084 | — | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized) | — | 0.031 | — | pH 8, 14 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | nicotinamide adenine dinucleotide (oxidized)NAD+ varied at fixed 10 µM SSA; Michaelis-Menten fit (eq. 1) | 68 | 0.032 | 2.1 × 10³ calc. | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), nicotinamide adenine dinucleotide (oxidized) |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehydesubinhibitory SSA (1-10 μM); NAD+ varied | 80 | 6 × 10⁻⁴ | 1.3 × 10⁵ calc. | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehydesubinhibitory SSA (1-10 μM); full-range NAD+ | 87 | 0.0015 | 5.8 × 10⁴ calc. | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehydeinhibitory SSA (12-200 μM) | 165 | — | — | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehydefull-range SSA and NAD+ | 166 | 0.004 | 4.2 × 10⁴ calc. | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehyde | 26 | 0.0012 | 2.2 × 10⁴ calc. | pH 8, 14 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |
| succinic semialdehyde dehydrogenase (hSSADH) | Homo sapiens | succinic semialdehydeSSA varied at fixed 500 µM NAD+ | 124 | 0.005 | 2.5 × 10⁴ calc. | pH 8, 25 °C | Open record: succinic semialdehyde dehydrogenase (hSSADH), succinic semialdehyde |