Values CatLog read from this paper
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
PMID 12808445doi:10.1038/nsb942Open in Browse
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CatLog read 8 records (24 values) from this paper: deoxycytidine kinase (dCK) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
EC 2.7.1.74, EC 2.7.1.76, EC 2.7.1.113
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| deoxycytidine kinase (dCK) | Homo sapiens | 2',3'-dideoxycytidine | 0.18 | 0.4068 | 0.4 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), 2',3'-dideoxycytidine |
| deoxycytidine kinase (dCK) | Homo sapiens | AraC | 0.26 | 0.0155 | 16.8 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), AraC |
| deoxycytidine kinase (dCK) | Homo sapiens | cytidine | 0.74 | 0.3827 | 1.9 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), cytidine |
| deoxycytidine kinase (dCK) | Homo sapiens | deoxycytidine | 0.03 | 0.0062 | 4.8 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), deoxycytidine |
| deoxycytidine kinase (dCK) | Homo sapiens | gemcitabine | 0.37 | 0.022 | 16.8 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK), gemcitabine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | AraC | 1.73 | 0.102 | 17 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, AraC |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | deoxycytidine | 0.93 | 0.004 | 232.5 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, deoxycytidine |
| deoxycytidine kinase (dCK)variant A100V/R104M/D133A | Homo sapiens | gemcitabine | 3.52 | 0.05 | 70.4 | pH 7.5, 37 °C | Open record: deoxycytidine kinase (dCK) variant A100V/R104M/D133A, gemcitabine |