Values CatLog read from this paper
Cofactor binding triggers a molecular switch to allosterically activate human UDP-α-D-glucose 6-dehydrogenase
PMID 23106432doi:10.1021/bi301067wOpen in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 4 records (8 values) from this paper: UDP-α-D-glucose 6-dehydrogenase (hUGDH) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| UDP-α-D-glucose 6-dehydrogenase (hUGDH) | Homo sapiens | NAD+ | 4.382 | 0.384 | 11.4 calc. | pH 8.7, 25 °C | Open record: UDP-α-D-glucose 6-dehydrogenase (hUGDH), NAD+ |
| UDP-α-D-glucose 6-dehydrogenase (hUGDH) | Homo sapiens | UDP-α-D-glucose | 3.145 | 0.0253 | 124 calc. | pH 8.7, 25 °C | Open record: UDP-α-D-glucose 6-dehydrogenase (hUGDH), UDP-α-D-glucose |
| UDP-α-D-glucose 6-dehydrogenase (hUGDH)variant K94E | Homo sapiens | NAD+ | 0.0217 | 6.3 | 0.0034 calc. | pH 8.7, 25 °C | Open record: UDP-α-D-glucose 6-dehydrogenase (hUGDH) variant K94E, NAD+ |
| UDP-α-D-glucose 6-dehydrogenase (hUGDH)variant K94E | Homo sapiens | UDP-α-D-glucose | 0.0235 | 2.21 | 0.0106 calc. | pH 8.7, 25 °C | Open record: UDP-α-D-glucose 6-dehydrogenase (hUGDH) variant K94E, UDP-α-D-glucose |