Values CatLog read from this paper
Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency
PMID 20522910doi:10.1074/jbc.m110.127779Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (14 values) from this paper: AKR1D1 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| AKR1D1 | Homo sapiens | 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione | 0.165 | 0.0151 | 11 | Open record: AKR1D1, 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione | |
| AKR1D1 | Homo sapiens | 17beta-hydroxyandrost-4-en-3-onefluorimetric assay; saturating NADPH; steroid 0.60-40 µM | 0.118 | 0.0027 | 43.8 | Open record: AKR1D1, 17beta-hydroxyandrost-4-en-3-one | |
| AKR1D1 | Homo sapiens | 17beta-hydroxyandrost-4-en-3-oneintact transfected HEK 293 cells in DMEM; untagged | — | 0.004 | — | Open record: AKR1D1, 17beta-hydroxyandrost-4-en-3-one | |
| AKR1D1 | Homo sapiens | 7alpha-hydroxycholest-4-en-3-one | — | 8 × 10⁻⁴ | — | Open record: AKR1D1, 7alpha-hydroxycholest-4-en-3-one | |
| AKR1D1variant P133R | Homo sapiens | 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione | 0.01 | 0.0013 | 7.7 | Open record: AKR1D1 variant P133R, 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione | |
| AKR1D1variant P133R | Homo sapiens | 17beta-hydroxyandrost-4-en-3-one | 0.045 | 0.0127 | 3.5 | Open record: AKR1D1 variant P133R, 17beta-hydroxyandrost-4-en-3-one |