Values CatLog read from this paper
Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding
PMID 15882147doi:10.1042/bj20042051Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (14 values) from this paper: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) | Homo sapiens | inosine 5'-monophosphate | 1.2 | 0.017 | 71 calc. | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) | Homo sapiens | inosine 5'-monophosphate | 0.9 | — | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) | Homo sapiens | NAD+ | — | 0.07 | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), NAD+ |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant A285T | Homo sapiens | inosine 5'-monophosphate | 0.9 | — | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant A285T, inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant D226N | Homo sapiens | inosine 5'-monophosphate | 0.7 | 0.012 | 58 calc. | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant D226N, inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant D226N | Homo sapiens | NAD+ | — | 0.05 | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant D226N, NAD+ |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant R224P | Homo sapiens | inosine 5'-monophosphate | 1.3 | 0.007 | 190 calc. | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant R224P, inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant R224P | Homo sapiens | NAD+ | — | 0.056 | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant R224P, NAD+ |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant V268I | Homo sapiens | inosine 5'-monophosphate | 0.8 | 0.011 | 73 calc. | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant V268I, inosine 5'-monophosphate |
| IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant V268I | Homo sapiens | NAD+ | — | 0.046 | — | pH 8, 37 °C | Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant V268I, NAD+ |