EC 1.1.1.205: IMP dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 133 records for EC 1.1.1.205 from 12 papers, for 11 organisms. Names in these papers: IMP dehydrogenase (IMPDH), IMP dehydrogenase type II (human IMPDH type II), IMP dehydrogenase (BaIMPDH), IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) and 14 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 160 records for EC 1.1.1.205 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.205 in Browse.

Papers

Papers with records for EC 1.1.1.205
Paper	Organisms	Records
The roles of conserved carboxylate residues in IMP dehydrogenase and identification of a transition state analog	Escherichia coli	24
Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase	Homo sapiens	18
A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity	Bacillus anthracis, Campylobacter jejuni and 2 more	16
Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding	Bacillus anthracis	16
Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding	Homo sapiens	10
Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase	Bacillus anthracis, Campylobacter jejuni and 3 more	10
Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products	Homo sapiens	10
A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5'-monophosphate dehydrogenases	Aspergillus nidulans, Penicillium brevicompactum	8
Characterization of human type I and type II IMP dehydrogenases	Homo sapiens	8
The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase	Tritrichomonas foetus	7
Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction	Tritrichomonas foetus	4
Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi	Borrelia burgdorferi	2

Records

Records for EC 1.1.1.205 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
AnIMPDH (inosine 5'-monophosphate dehydrogenase)	Aspergillus nidulans	inosine 5'-monophosphate	1.9	0.015	130 calc.	pH 8, 25 °C	PMID 31675145	Open record: AnIMPDH (inosine 5'-monophosphate dehydrogenase), inosine 5'-monophosphate
AnIMPDH (inosine 5'-monophosphate dehydrogenase)	Aspergillus nidulans	nicotinamide adenine dinucleotide (oxidized)	—	0.12	—	pH 8, 25 °C	PMID 31675145	Open record: AnIMPDH (inosine 5'-monophosphate dehydrogenase), nicotinamide adenine dinucleotide (oxidized)
AnIMPDH (inosine 5'-monophosphate dehydrogenase)variant A267S	Aspergillus nidulans	inosine 5'-monophosphate	1.9	0.015	130 calc.	pH 8, 25 °C	PMID 31675145	Open record: AnIMPDH (inosine 5'-monophosphate dehydrogenase) variant A267S, inosine 5'-monophosphate
AnIMPDH (inosine 5'-monophosphate dehydrogenase)variant A267S	Aspergillus nidulans	nicotinamide adenine dinucleotide (oxidized)	—	0.19	—	pH 8, 25 °C	PMID 31675145	Open record: AnIMPDH (inosine 5'-monophosphate dehydrogenase) variant A267S, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (BaIMPDH)	Bacillus anthracis	inosine 5'-monophosphate	5.3	0.064	83 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH), inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)	Bacillus anthracis	inosine 5'-monophosphate	2.8	0.059	47 calc.		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH), inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)	Bacillus anthracis	NAD+	—	0.55	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH), NAD+
IMP dehydrogenase (BaIMPDH)	Bacillus anthracis	NAD+	—	0.59	—		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH), NAD+
IMP dehydrogenase (BaIMPDH)variant L413A	Bacillus anthracis	inosine 5'-monophosphate	1.6	0.069	23 calc.		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413A, inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)variant L413A	Bacillus anthracis	NAD+	—	0.83	—		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413A, NAD+
IMP dehydrogenase (BaIMPDH)variant L413F	Bacillus anthracis	inosine 5'-monophosphate	2.6	0.07	37 calc.		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413F, inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)variant L413F	Bacillus anthracis	NAD+	—	2.1	—		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413F, NAD+
IMP dehydrogenase (BaIMPDH)variant L413V	Bacillus anthracis	inosine 5'-monophosphate	3.7	0.085	44 calc.		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413V, inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)variant L413V	Bacillus anthracis	NAD+	—	3.3	—		PMID 39879323	Open record: IMP dehydrogenase (BaIMPDH) variant L413V, NAD+
IMP dehydrogenase (BaIMPDH)ΔL (CBS domain deletion)	Bacillus anthracis	inosine 5'-monophosphate	4.5	0.15	30 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH) ΔL (CBS domain deletion), inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)ΔL (CBS domain deletion)	Bacillus anthracis	NAD+	—	0.46	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH) ΔL (CBS domain deletion), NAD+
IMP dehydrogenase (BaIMPDH)ΔS (CBS domain deletion)	Bacillus anthracis	inosine 5'-monophosphate	6.1	0.061	100 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH) ΔS (CBS domain deletion), inosine 5'-monophosphate
IMP dehydrogenase (BaIMPDH)ΔS (CBS domain deletion)	Bacillus anthracis	NAD+	—	0.56	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (BaIMPDH) ΔS (CBS domain deletion), NAD+
IMP dehydrogenase (CjIMPDH)	Campylobacter jejuni	inosine 5'-monophosphate	2.2	0.055	40 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (CjIMPDH), inosine 5'-monophosphate
IMP dehydrogenase (CjIMPDH)	Campylobacter jejuni	NAD+	—	0.22	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (CjIMPDH), NAD+
IMP dehydrogenase (CjIMPDH)ΔS (CBS domain deletion)	Campylobacter jejuni	inosine 5'-monophosphate	1.9	0.027	70 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (CjIMPDH) ΔS (CBS domain deletion), inosine 5'-monophosphate
IMP dehydrogenase (CjIMPDH)ΔS (CBS domain deletion)	Campylobacter jejuni	NAD+	—	0.52	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (CjIMPDH) ΔS (CBS domain deletion), NAD+
IMP dehydrogenase (ClpIMPDH)	Clostridium perfringens	inosine 5'-monophosphate	2.9	0.1	29 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (ClpIMPDH), inosine 5'-monophosphate
IMP dehydrogenase (ClpIMPDH)	Clostridium perfringens	NAD+	—	0.37	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (ClpIMPDH), NAD+
IMP dehydrogenase (ClpIMPDH)ΔL (CBS domain deletion)	Clostridium perfringens	inosine 5'-monophosphate	1.8	0.049	37 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (ClpIMPDH) ΔL (CBS domain deletion), inosine 5'-monophosphate
IMP dehydrogenase (ClpIMPDH)ΔL (CBS domain deletion)	Clostridium perfringens	NAD+	—	0.51	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (ClpIMPDH) ΔL (CBS domain deletion), NAD+
IMP dehydrogenase (IMPDH)	Escherichia coli	inosine 5'-monophosphate	13	0.061	210 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH), inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)	Escherichia coli	nicotinamide adenine dinucleotide	—	2	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH), nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D138A	Escherichia coli	inosine 5'-monophosphate	7.1	0.044	160 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D138A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D138A	Escherichia coli	nicotinamide adenine dinucleotide	—	1.4	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D138A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D13A	Escherichia coli	inosine 5'-monophosphate	0.7	0.052	13 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D13A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D13A	Escherichia coli	nicotinamide adenine dinucleotide	—	5.7	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D13A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D200A	Escherichia coli	inosine 5'-monophosphate	14	0.044	320 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D200A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D200A	Escherichia coli	nicotinamide adenine dinucleotide	—	1.5	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D200A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D243A	Escherichia coli	inosine 5'-monophosphate	12	0.056	210 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D243A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D243A	Escherichia coli	nicotinamide adenine dinucleotide	—	2	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D243A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D248A	Escherichia coli	inosine 5'-monophosphate	0.1	0.021	4.8 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D248A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D248A	Escherichia coli	nicotinamide adenine dinucleotide	—	6.3	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D248A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D338A	Escherichia coli	inosine 5'-monophosphate	0.02	0.71	0.028 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D338A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D338A	Escherichia coli	nicotinamide adenine dinucleotide	—	3.3	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D338A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant D50A	Escherichia coli	inosine 5'-monophosphate	1.2	0.061	20 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D50A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant D50A	Escherichia coli	nicotinamide adenine dinucleotide	—	4.1	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant D50A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant E369A	Escherichia coli	inosine 5'-monophosphate	7.1	0.053	130 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E369A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E369A	Escherichia coli	nicotinamide adenine dinucleotide	—	2	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E369A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant E373A	Escherichia coli	inosine 5'-monophosphate	7.1	0.059	120 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E373A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E373A	Escherichia coli	nicotinamide adenine dinucleotide	—	1.6	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E373A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant E469A	Escherichia coli	inosine 5'-monophosphate	14	0.049	290 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E469A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E469A	Escherichia coli	nicotinamide adenine dinucleotide	—	11	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E469A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant E54A	Escherichia coli	inosine 5'-monophosphate	14	0.087	160 calc.	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E54A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E54A	Escherichia coli	nicotinamide adenine dinucleotide	—	2.4	—	pH 8, 25 °C	PMID 9341229	Open record: IMP dehydrogenase (IMPDH) variant E54A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant E323A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.031	—	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant E323A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E323A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	1.1	0.3	3.7 calc.	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant E323A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant Q324A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.028	—	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant Q324A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant Q324A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.43	0.12	3.6 calc.	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant Q324A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant R322A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.0076	—	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant R322A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant R322A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.36	0.91	0.40 calc.	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant R322A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant R322E	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.009	2.6	0.0035 calc.	pH 8, 25 °C	PMID 21062060	Open record: IMP dehydrogenase (IMPDH) variant R322E, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant R418A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.003	—	pH 8, 25 °C	PMID 15078097	Open record: IMP dehydrogenase (IMPDH) variant R418A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant R418A	Tritrichomonas foetus	nicotinamide adenine dinucleotide	0.004	0.0016	2.5 calc.	pH 8, 25 °C	PMID 15078097	Open record: IMP dehydrogenase (IMPDH) variant R418A, nicotinamide adenine dinucleotide
IMP dehydrogenase (IMPDH)variant Y419F	Tritrichomonas foetus	inosine 5'-monophosphate	—	7 × 10⁻⁴	—	pH 8, 25 °C	PMID 15078097	Open record: IMP dehydrogenase (IMPDH) variant Y419F, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant Y419F	Tritrichomonas foetus	nicotinamide adenine dinucleotide	0.22	0.07	3.1 calc.	pH 8, 25 °C	PMID 15078097	Open record: IMP dehydrogenase (IMPDH) variant Y419F, nicotinamide adenine dinucleotide
IMP dehydrogenase (VcIMPDH)ΔL (CBS domain deletion)	Vibrio cholerae	inosine 5'-monophosphate	5.2	0.087	60 calc.	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (VcIMPDH) ΔL (CBS domain deletion), inosine 5'-monophosphate
IMP dehydrogenase (VcIMPDH)ΔL (CBS domain deletion)	Vibrio cholerae	NAD+	—	1.1	—	pH 8, 25 °C	PMID 25572472	Open record: IMP dehydrogenase (VcIMPDH) ΔL (CBS domain deletion), NAD+
IMP dehydrogenase type I	Homo sapiens	inosine 5'-monophosphate	—	0.018	—	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type I, inosine 5'-monophosphate
IMP dehydrogenase type I	Homo sapiens	NAD+	1.5	0.046	33 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type I, NAD+
IMP dehydrogenase type I	Homo sapiens	nicotinamide guanine dinucleotide	0.8	2.3	0.35 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type I, nicotinamide guanine dinucleotide
IMP dehydrogenase type I	Homo sapiens	nicotinamide hypoxanthine dinucleotide	1.2	1	1.2 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type I, nicotinamide hypoxanthine dinucleotide
IMP dehydrogenase type II	Homo sapiens	inosine 5'-monophosphate	—	0.0093	—	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type II, inosine 5'-monophosphate
IMP dehydrogenase type II	Homo sapiens	NAD+	1.3	0.032	41 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type II, NAD+
IMP dehydrogenase type II	Homo sapiens	nicotinamide guanine dinucleotide	0.6	5	0.12 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type II, nicotinamide guanine dinucleotide
IMP dehydrogenase type II	Homo sapiens	nicotinamide hypoxanthine dinucleotide	0.8	1.4	0.57 calc.	pH 8, 37 °C	PMID 7903306	Open record: IMP dehydrogenase type II, nicotinamide hypoxanthine dinucleotide
IMP dehydrogenase type II (human IMPDH type II)	Homo sapiens	inosine 5'-monophosphate	0.41	0.013	32 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II), inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)	Homo sapiens	NAD+	—	0.021	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II), NAD+
IMP dehydrogenase type II (human IMPDH type II)variant A462T	Homo sapiens	inosine 5'-monophosphate	0.61	0.033	18 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant A462T, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant A462T	Homo sapiens	NAD+	—	0.037	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant A462T, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant D255G	Homo sapiens	inosine 5'-monophosphate	0.35	0.0168	21 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant D255G, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant D255G	Homo sapiens	NAD+	—	0.01	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant D255G, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant F456S/D470G	Homo sapiens	inosine 5'-monophosphate	0.17	0.008	21 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant F456S/D470G, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant F456S/D470G	Homo sapiens	NAD+	—	0.017	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant F456S/D470G, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant G340E	Homo sapiens	inosine 5'-monophosphate	0.55	0.007	79 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant G340E, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant G340E	Homo sapiens	NAD+	—	0.012	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant G340E, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant L30F	Homo sapiens	NAD+	0.075	0.015	5.0 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant L30F, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant L30F/Q277R	Homo sapiens	NAD+	0.1	0.18	0.56 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant L30F/Q277R, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant M482I	Homo sapiens	inosine 5'-monophosphate	0.4	0.023	17 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant M482I, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant M482I	Homo sapiens	NAD+	—	0.01	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant M482I, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant Q277R	Homo sapiens	inosine 5'-monophosphate	0.13	0.08	1.6 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant Q277R	Homo sapiens	NAD+	—	0.105	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R, NAD+
IMP dehydrogenase type II (human IMPDH type II)variant Q277R/A462T	Homo sapiens	inosine 5'-monophosphate	0.51	0.085	6.0 calc.	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R/A462T, inosine 5'-monophosphate
IMP dehydrogenase type II (human IMPDH type II)variant Q277R/A462T	Homo sapiens	NAD+	—	0.32	—	pH 8, 25 °C	PMID 8995388	Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R/A462T, NAD+
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)	Homo sapiens	inosine 5'-monophosphate	1.2	0.017	71 calc.	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)	Homo sapiens	inosine 5'-monophosphate	0.9	—	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)	Homo sapiens	NAD+	—	0.07	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I), NAD+
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant A285T	Homo sapiens	inosine 5'-monophosphate	0.9	—	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant A285T, inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant D226N	Homo sapiens	inosine 5'-monophosphate	0.7	0.012	58 calc.	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant D226N, inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant D226N	Homo sapiens	NAD+	—	0.05	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant D226N, NAD+
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant R224P	Homo sapiens	inosine 5'-monophosphate	1.3	0.007	190 calc.	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant R224P, inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant R224P	Homo sapiens	NAD+	—	0.056	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant R224P, NAD+
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant V268I	Homo sapiens	inosine 5'-monophosphate	0.8	0.011	73 calc.	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant V268I, inosine 5'-monophosphate
IMPDH1 (inosine 5'-monophosphate dehydrogenase type I)variant V268I	Homo sapiens	NAD+	—	0.046	—	pH 8, 37 °C	PMID 15882147	Open record: IMPDH1 (inosine 5'-monophosphate dehydrogenase type I) variant V268I, NAD+
inosine 5'-monophosphate dehydrogenase (BaIMPDH)	Bacillus anthracis	inosine 5'-monophosphate	—	0.083	—	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase (BaIMPDH)	Bacillus anthracis	inosine 5′-monophosphate	—	0.0582	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), inosine 5′-monophosphate
inosine 5'-monophosphate dehydrogenase (BaIMPDH)	Bacillus anthracis	NAD+	—	0.683	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), NAD+
inosine 5'-monophosphate dehydrogenase (BaIMPDH)	Bacillus anthracis	nicotinamide adenine dinucleotide (oxidized)	3	0.7	4.3 calc.	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), nicotinamide adenine dinucleotide (oxidized)
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413A	Bacillus anthracis	inosine 5′-monophosphate	—	0.0576	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413A, inosine 5′-monophosphate
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413A	Bacillus anthracis	NAD+	—	1.1	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413A, NAD+
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413F	Bacillus anthracis	inosine 5′-monophosphate	—	0.0701	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413F, inosine 5′-monophosphate
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413F	Bacillus anthracis	NAD+	—	2.06	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413F, NAD+
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413V	Bacillus anthracis	inosine 5′-monophosphate	—	0.0851	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413V, inosine 5′-monophosphate
inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413V	Bacillus anthracis	NAD+	—	3.65	—	pH 8	PMID 39879323	Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413V, NAD+
inosine 5'-monophosphate dehydrogenase (CjIMPDH)	Campylobacter jejuni	inosine 5'-monophosphate	—	0.012	—	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (CjIMPDH), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase (CjIMPDH)	Campylobacter jejuni	nicotinamide adenine dinucleotide (oxidized)	2.2	0.066	33 calc.	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (CjIMPDH), nicotinamide adenine dinucleotide (oxidized)
inosine 5'-monophosphate dehydrogenase (CpIMPDH)	Cryptosporidium parvum	inosine 5'-monophosphate	—	0.01	—	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (CpIMPDH), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase (CpIMPDH)	Cryptosporidium parvum	nicotinamide adenine dinucleotide (oxidized)	3.2	0.045	71 calc.	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (CpIMPDH), nicotinamide adenine dinucleotide (oxidized)
inosine 5'-monophosphate dehydrogenase (IMPDH)	Borrelia burgdorferi	inosine 5'-monophosphate	—	0.029	—	pH 8, 37 °C	PMID 9268334	Open record: inosine 5'-monophosphate dehydrogenase (IMPDH), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase (IMPDH)	Borrelia burgdorferi	nicotinamide adenine dinucleotide (NAD+)	2.6	1.1	2.4 calc.	pH 8, 37 °C	PMID 9268334	Open record: inosine 5'-monophosphate dehydrogenase (IMPDH), nicotinamide adenine dinucleotide (NAD+)
inosine 5'-monophosphate dehydrogenase (TfIMPDH)	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.0063	—	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (TfIMPDH), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase (TfIMPDH)	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.7	0.08	8.8 calc.	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase (TfIMPDH), nicotinamide adenine dinucleotide (oxidized)
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	3-pyridinealdehyde adenine dinucleotide	0.48	0.27	1.8	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, 3-pyridinealdehyde adenine dinucleotide
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	acetylpyridine adenine dinucleotide	0.62	0.03	21	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, acetylpyridine adenine dinucleotide
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	inosine 5'-monophosphateIMP + NAD; cosubstrate NAD	—	0.004	98	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	inosine 5'-monophosphateIMP + thio-NAD; cosubstrate thio-NAD	—	0.004	79	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	inosine 5'-monophosphateIMP + acetylpyridine-NAD; cosubstrate acetylpyridine-NAD	—	0.034	23	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	inosine 5'-monophosphateIMP + pyridinealdehyde-NAD; cosubstrate pyridinealdehyde-NAD	—	0.041	12	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	inosine 5'-monophosphateIMP + NHD; cosubstrate NHD	—	0.008	56	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	nicotinamide adenine dinucleotide	0.39	0.006	65	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, nicotinamide adenine dinucleotide
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	nicotinamide hypoxanthine dinucleotide	0.34	0.59	0.57	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, nicotinamide hypoxanthine dinucleotide
inosine 5'-monophosphate dehydrogenase type II	Homo sapiens	thionicotinamide adenine dinucleotide	0.34	0.12	2.8	pH 8, 25 °C	PMID 9214292	Open record: inosine 5'-monophosphate dehydrogenase type II, thionicotinamide adenine dinucleotide
inosine 5'-monophosphate dehydrogenase type II (human IMPDH2)	Homo sapiens	inosine 5'-monophosphate	—	0.0033	—	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase type II (human IMPDH2), inosine 5'-monophosphate
inosine 5'-monophosphate dehydrogenase type II (human IMPDH2)	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)	0.22	0.007	31 calc.	pH 8, 25 °C	PMID 30746940	Open record: inosine 5'-monophosphate dehydrogenase type II (human IMPDH2), nicotinamide adenine dinucleotide (oxidized)
PbIMPDHA (inosine 5'-monophosphate dehydrogenase A)	Penicillium brevicompactum	inosine 5'-monophosphate	2.7	0.093	29 calc.	pH 8, 25 °C	PMID 31675145	Open record: PbIMPDHA (inosine 5'-monophosphate dehydrogenase A), inosine 5'-monophosphate
PbIMPDHA (inosine 5'-monophosphate dehydrogenase A)	Penicillium brevicompactum	nicotinamide adenine dinucleotide (oxidized)	—	0.4	—	pH 8, 25 °C	PMID 31675145	Open record: PbIMPDHA (inosine 5'-monophosphate dehydrogenase A), nicotinamide adenine dinucleotide (oxidized)
PbIMPDHA (inosine 5'-monophosphate dehydrogenase A)variant S267A	Penicillium brevicompactum	inosine 5'-monophosphate	1.6	0.079	20 calc.	pH 8, 25 °C	PMID 31675145	Open record: PbIMPDHA (inosine 5'-monophosphate dehydrogenase A) variant S267A, inosine 5'-monophosphate
PbIMPDHA (inosine 5'-monophosphate dehydrogenase A)variant S267A	Penicillium brevicompactum	nicotinamide adenine dinucleotide (oxidized)	—	0.33	—	pH 8, 25 °C	PMID 31675145	Open record: PbIMPDHA (inosine 5'-monophosphate dehydrogenase A) variant S267A, nicotinamide adenine dinucleotide (oxidized)