Values CatLog read from this paper

The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5'-monophosphate dehydrogenase

PMID 21062060doi:10.1021/bi101590cOpen in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (11 values) from this paper: IMP dehydrogenase (IMPDH) from Tritrichomonas foetus.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 1.1.1.205

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
IMP dehydrogenase (IMPDH)variant E323A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.031	—	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant E323A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant E323A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	1.1	0.3	3.7 calc.	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant E323A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant Q324A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.028	—	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant Q324A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant Q324A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.43	0.12	3.6 calc.	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant Q324A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant R322A	Tritrichomonas foetus	inosine 5'-monophosphate	—	0.0076	—	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant R322A, inosine 5'-monophosphate
IMP dehydrogenase (IMPDH)variant R322A	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.36	0.91	0.40 calc.	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant R322A, nicotinamide adenine dinucleotide (oxidized)
IMP dehydrogenase (IMPDH)variant R322E	Tritrichomonas foetus	nicotinamide adenine dinucleotide (oxidized)	0.009	2.6	0.0035 calc.	pH 8, 25 °C	Open record: IMP dehydrogenase (IMPDH) variant R322E, nicotinamide adenine dinucleotide (oxidized)