Values CatLog read from this paper
Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase
PMID 8995388doi:10.1074/jbc.272.2.961Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (28 values) from this paper: IMP dehydrogenase type II (human IMPDH type II) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 10 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| IMP dehydrogenase type II (human IMPDH type II) | Homo sapiens | inosine 5'-monophosphate | 0.41 | 0.013 | 32 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II), inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II) | Homo sapiens | NAD+ | — | 0.021 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II), NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant A462T | Homo sapiens | inosine 5'-monophosphate | 0.61 | 0.033 | 18 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant A462T, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant A462T | Homo sapiens | NAD+ | — | 0.037 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant A462T, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant D255G | Homo sapiens | inosine 5'-monophosphate | 0.35 | 0.0168 | 21 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant D255G, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant D255G | Homo sapiens | NAD+ | — | 0.01 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant D255G, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant F456S/D470G | Homo sapiens | inosine 5'-monophosphate | 0.17 | 0.008 | 21 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant F456S/D470G, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant F456S/D470G | Homo sapiens | NAD+ | — | 0.017 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant F456S/D470G, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant G340E | Homo sapiens | inosine 5'-monophosphate | 0.55 | 0.007 | 79 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant G340E, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant G340E | Homo sapiens | NAD+ | — | 0.012 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant G340E, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant L30F | Homo sapiens | NAD+ | 0.075 | 0.015 | 5.0 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant L30F, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant L30F/Q277R | Homo sapiens | NAD+ | 0.1 | 0.18 | 0.56 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant L30F/Q277R, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant M482I | Homo sapiens | inosine 5'-monophosphate | 0.4 | 0.023 | 17 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant M482I, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant M482I | Homo sapiens | NAD+ | — | 0.01 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant M482I, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant Q277R | Homo sapiens | inosine 5'-monophosphate | 0.13 | 0.08 | 1.6 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant Q277R | Homo sapiens | NAD+ | — | 0.105 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R, NAD+ |
| IMP dehydrogenase type II (human IMPDH type II)variant Q277R/A462T | Homo sapiens | inosine 5'-monophosphate | 0.51 | 0.085 | 6.0 calc. | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R/A462T, inosine 5'-monophosphate |
| IMP dehydrogenase type II (human IMPDH type II)variant Q277R/A462T | Homo sapiens | NAD+ | — | 0.32 | — | pH 8, 25 °C | Open record: IMP dehydrogenase type II (human IMPDH type II) variant Q277R/A462T, NAD+ |