Values CatLog read from this paper
Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding
PMID 39879323doi:10.1021/acsinfecdis.4c00636Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 16 records (20 values) from this paper: IMP dehydrogenase (BaIMPDH), inosine 5'-monophosphate dehydrogenase (BaIMPDH) from Bacillus anthracis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 4 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| IMP dehydrogenase (BaIMPDH) | Bacillus anthracis | inosine 5'-monophosphate | 2.8 | 0.059 | 47 calc. | Open record: IMP dehydrogenase (BaIMPDH), inosine 5'-monophosphate | |
| IMP dehydrogenase (BaIMPDH) | Bacillus anthracis | NAD+ | — | 0.59 | — | Open record: IMP dehydrogenase (BaIMPDH), NAD+ | |
| IMP dehydrogenase (BaIMPDH)variant L413A | Bacillus anthracis | inosine 5'-monophosphate | 1.6 | 0.069 | 23 calc. | Open record: IMP dehydrogenase (BaIMPDH) variant L413A, inosine 5'-monophosphate | |
| IMP dehydrogenase (BaIMPDH)variant L413A | Bacillus anthracis | NAD+ | — | 0.83 | — | Open record: IMP dehydrogenase (BaIMPDH) variant L413A, NAD+ | |
| IMP dehydrogenase (BaIMPDH)variant L413F | Bacillus anthracis | inosine 5'-monophosphate | 2.6 | 0.07 | 37 calc. | Open record: IMP dehydrogenase (BaIMPDH) variant L413F, inosine 5'-monophosphate | |
| IMP dehydrogenase (BaIMPDH)variant L413F | Bacillus anthracis | NAD+ | — | 2.1 | — | Open record: IMP dehydrogenase (BaIMPDH) variant L413F, NAD+ | |
| IMP dehydrogenase (BaIMPDH)variant L413V | Bacillus anthracis | inosine 5'-monophosphate | 3.7 | 0.085 | 44 calc. | Open record: IMP dehydrogenase (BaIMPDH) variant L413V, inosine 5'-monophosphate | |
| IMP dehydrogenase (BaIMPDH)variant L413V | Bacillus anthracis | NAD+ | — | 3.3 | — | Open record: IMP dehydrogenase (BaIMPDH) variant L413V, NAD+ | |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH) | Bacillus anthracis | inosine 5′-monophosphate | — | 0.0582 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), inosine 5′-monophosphate |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH) | Bacillus anthracis | NAD+ | — | 0.683 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH), NAD+ |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413A | Bacillus anthracis | inosine 5′-monophosphate | — | 0.0576 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413A, inosine 5′-monophosphate |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413A | Bacillus anthracis | NAD+ | — | 1.1 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413A, NAD+ |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413F | Bacillus anthracis | inosine 5′-monophosphate | — | 0.0701 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413F, inosine 5′-monophosphate |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413F | Bacillus anthracis | NAD+ | — | 2.06 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413F, NAD+ |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413V | Bacillus anthracis | inosine 5′-monophosphate | — | 0.0851 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413V, inosine 5′-monophosphate |
| inosine 5'-monophosphate dehydrogenase (BaIMPDH)variant L413V | Bacillus anthracis | NAD+ | — | 3.65 | — | pH 8 | Open record: inosine 5'-monophosphate dehydrogenase (BaIMPDH) variant L413V, NAD+ |