CatLogenzyme kinetics catalog

Values CatLog read from this paper

Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studies

PMID 19932622doi:10.1016/j.bmc.2009.10.056Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 22 records (46 values) from this paper: P99 β-lactamase (class C β-lactamase), R61 DD-peptidase, R39 DD-peptidase and 1 more from Enterobacter cloacae, Streptomyces sp. R61, Actinomadura sp. R39.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.5.2.6

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-(2-benzylcarbamoyl-3-phenyl-propionyloxy)-benzoic acid0.050.002619pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-(2-benzylcarbamoyl-propionyloxy)-benzoic acid1.170.0621.3pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-(2-benzylcarbamoyl-propionyloxy)-benzoic acid6.62.82.36pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-[2-(N,N-dibenzylaminocarbonyl)-ethanoyl]-oxybenzoic acid0.250.0327.9pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-[2-(N-methyl-benzylaminocarbonyl)-ethanoyl]-oxybenzoic acid0.330.70.47pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-carboxylphenyl 1-benzyl-2-oxo-pyrrolidine-3-carboxylate0.122.50.05pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-carboxylphenyl N-benzyl-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate0.411.40.29pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-hydroxycarbonylphenyl N-benzyl-2-methoxymalonamate——7.4pH 7.5, 25 °COpen
P99 β-lactamase (class C β-lactamase)Enterobacter cloacae3-hydroxycarbonylphenyl N-benzyl-2-methoxymalonamate——2.9pH 7.5, 25 °COpen
R39 DD-peptidaseActinomadura sp. R393-(2-benzylcarbamoyl-propionyloxy)-benzoic acid——0.728pH 7.5, 25 °COpen
R39 DD-peptidaseActinomadura sp. R393-[2-(N-methyl-benzylaminocarbonyl)-ethanoyl]-oxybenzoic acid——0.003pH 7.5, 25 °COpen
R39 DD-peptidaseActinomadura sp. R393-carboxylphenyl 1-benzyl-2-oxo-pyrrolidine-3-carboxylate——0.008pH 7.5, 25 °COpen
R39 DD-peptidaseActinomadura sp. R393-hydroxycarbonylphenyl N-benzyl-2-methoxymalonamate2.680.05350pH 7.5, 25 °COpen
R61 DD-peptidaseStreptomyces sp. R613-(2-benzylcarbamoyl-propionyloxy)-benzoic acid7.630.3223.7pH 7.5, 25 °COpen
R61 DD-peptidaseStreptomyces sp. R613-(2-benzylcarbamoyl-propionyloxy)-benzoic acid0.120.091.31pH 7.5, 25 °COpen
R61 DD-peptidaseStreptomyces sp. R613-carboxylphenyl 1-benzyl-2-oxo-pyrrolidine-3-carboxylate——0.0178pH 7.5, 25 °COpen
R61 DD-peptidaseStreptomyces sp. R613-carboxylphenyl N-benzyl-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate——0.021pH 7.5, 25 °COpen
R61 DD-peptidaseStreptomyces sp. R613-hydroxycarbonylphenyl N-benzyl-2-methoxymalonamate9.40.2833pH 7.5, 25 °COpen
TEM-2 β-lactamase (class A β-lactamase)—3-(2-benzylcarbamoyl-3-phenyl-propionyloxy)-benzoic acid——0.0047pH 7.5, 25 °COpen
TEM-2 β-lactamase (class A β-lactamase)—3-(2-benzylcarbamoyl-propionyloxy)-benzoic acid——0.0036pH 7.5, 25 °COpen
TEM-2 β-lactamase (class A β-lactamase)—3-[2-(N,N-dibenzylaminocarbonyl)-ethanoyl]-oxybenzoic acid0.211.80.12pH 7.5, 25 °COpen
TEM-2 β-lactamase (class A β-lactamase)—3-carboxylphenyl 1-benzyl-2-oxo-pyrrolidine-3-carboxylate——5.4 × 10⁻⁴pH 7.5, 25 °COpen