Values CatLog read from this paper
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification
PMID 24919140doi:10.1021/cb500257sOpen in Browse
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CatLog read 3 records (9 values) from this paper: cocaine esterase (CocE).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cocaine esterase (CocE)variant T172R/G173Q | — | (-)-cocaine | 43 | 0.0029 | 1.53 × 10⁴ | 37 °C | Open record: cocaine esterase (CocE) variant T172R/G173Q, (-)-cocaine |
| cocaine esterase (CocE)variant T172R/G173Q/G4C/S10C | — | (-)-cocaine | 39 | 0.0021 | 1.8 × 10⁴ | 37 °C | Open record: cocaine esterase (CocE) variant T172R/G173Q/G4C/S10C, (-)-cocaine |
| cocaine esterase (CocE)variant T172R/G173Q/L196C/I301C | — | (-)-cocaine | 57.5 | 0.0015 | 3.8 × 10⁴ | 37 °C | Open record: cocaine esterase (CocE) variant T172R/G173Q/L196C/I301C, (-)-cocaine |