Values CatLog read from this paper
Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer
PMID 29661938doi:10.1074/jbc.m117.812016Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 5 records (13 values) from this paper: β-tryptase (βI-tryptase) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| β-tryptase (βI-tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 87 | 0.47 | 180 | pH 8 | Open record: β-tryptase (βI-tryptase), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 50 | 0.82 | 61 | pH 8 | Open record: β-tryptase (βI-tryptase) variant I99C, H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C/Y75A/Y37bA (I99C*: Cys-99 cysteinylated, monomer) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 6.7 | 1.6 | 4 | pH 8 | Open record: β-tryptase (βI-tryptase) variant I99C/Y75A/Y37bA (I99C*: Cys-99 cysteinylated, monomer), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C/Y75A/Y37bA (disulfide-linked dimer) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 5.8 | — | — | pH 8 | Open record: β-tryptase (βI-tryptase) variant I99C/Y75A/Y37bA (disulfide-linked dimer), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant Y75C | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 37 | 0.32 | 120 | pH 8 | Open record: β-tryptase (βI-tryptase) variant Y75C, H-D-Ile-Pro-Arg-p-nitroanilide |