EC 3.4.21.59: Tryptase
HydrolasesOpen in Browse
CatLog read 70 records for EC 3.4.21.59 from 5 papers, for 2 organisms. Names in these papers: mast cell tryptase, tryptase (human lung tryptase), mouse mast cell protease 6 (mMCP-6, mouse tryptase), β-tryptase and 2 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 4 records for EC 3.4.21.59 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.21.59 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The heterogeneity of mast cell tryptase from human lung and skin | Homo sapiens | 36 |
| Heparin antagonists are potent inhibitors of mast cell tryptase | Homo sapiens, Mus musculus | 17 |
| The influence of substrate peptide length on human beta-tryptase specificity | Homo sapiens | 8 |
| Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer | Homo sapiens | 5 |
| Definition of the extended substrate specificity determinants for beta-tryptases I and II | Homo sapiens | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| mast cell tryptase | Homo sapiens | D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilidepreparation L1 | 51 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilidepreparation L2 | 24.1 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilidepreparation S1 | 59.5 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilidepreparation S2 | 27.1 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-phenylalanyl-pipecolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilidepreparation L1 | 5 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilidepreparation L2 | 2.8 | 1.64 | 1.69 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilidepreparation S1 | 5.3 | 2.59 | 2.06 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilidepreparation S2 | 5.2 | 1.75 | 3 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-prolyl-L-phenylalanyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-valyl-L-leucyl-L-arginine 4-nitroanilidepreparation L1 | 21.1 | 3.49 | 6.05 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-valyl-L-leucyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-valyl-L-leucyl-L-arginine 4-nitroanilidepreparation L2 | 7.1 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-valyl-L-leucyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-valyl-L-leucyl-L-arginine 4-nitroanilidepreparation S1 | 31 | 3.11 | 9.97 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-valyl-L-leucyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | D-valyl-L-leucyl-L-arginine 4-nitroanilidepreparation S2 | 16.3 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, D-valyl-L-leucyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-glycyl-L-arginine 4-nitroanilidepreparation L1 | 60.6 | 5.03 | 12 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-glycyl-L-arginine 4-nitroanilidepreparation L2 | — | — | 4.4 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-glycyl-L-arginine 4-nitroanilidepreparation S1 | 183 | 10.5 | 17.4 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-glycyl-L-arginine 4-nitroanilidepreparation S2 | — | — | 8.1 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilidepreparation L1 | 56.4 | 0.37 | 151 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilidepreparation L2 | 56.9 | 0.64 | 88 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilidepreparation S1 | 106.6 | 0.42 | 251 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilidepreparation S2 | 100.7 | 0.42 | 239 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, L-pyroglutamyl-L-prolyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide[S] 0.025–4.0 mM; preparation L1 | 1.9 | 0.04 | 44.5 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide[S] 0.025–1.0 mM; preparation L2 | 3 | 0.23 | 18.2 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide[S] 0.025–4.0 mM; preparation S1 | 10.3 | 0.36 | 28.8 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide[S] 0.025–1.0 mM; preparation S2 | 5.4 | 0.15 | 35.9 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-benzyloxycarbonyl-D-arginyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilidepreparation L1 | 40 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilidepreparation L2 | 27.9 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilidepreparation S1 | 75.5 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilidepreparation S2 | 45.9 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, N-tosyl-glycyl-L-prolyl-L-lysine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-benzoyl-DL-arginine 4-nitroanilidepreparation L1 | 1.66 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-benzoyl-DL-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-benzoyl-DL-arginine 4-nitroanilidepreparation L2 | 2.51 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-benzoyl-DL-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-benzoyl-DL-arginine 4-nitroanilidepreparation S1 | 8.9 | 4.85 | 1.84 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-benzoyl-DL-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-benzoyl-DL-arginine 4-nitroanilidepreparation S2 | 6.51 | 2.36 | 2.76 | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-benzoyl-DL-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilidepreparation L1 | 22.9 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilidepreparation L2 | 15.2 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilidepreparation S1 | 43.8 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilide |
| mast cell tryptase | Homo sapiens | Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilidepreparation S2 | 30.5 | — | — | pH 8 | PMID 12605678 | Open record: mast cell tryptase, Nalpha-methoxycarbonyl-L-norleucyl-glycyl-L-arginine 4-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilidewithout inhibitor | 4.3 | 0.27 | 16 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 5.8 | 0.41 | 14 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 5.1 | 0.53 | 9.6 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 3.9 | 0.64 | 6.1 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 3.6 | 0.2 | 18 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 2.6 | 0.21 | 12 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 1.5 | 0.21 | 7.1 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| mouse mast cell protease 6 (mMCP-6, mouse tryptase) | Mus musculus | N-p-tosyl-Gly-Pro-Lys-p-nitroanilideapparent kcat; apparent Km | 0.74 | 0.19 | 3.9 calc. | pH 6 | PMID 11401583 | Open record: mouse mast cell protease 6 (mMCP-6, mouse tryptase), N-p-tosyl-Gly-Pro-Lys-p-nitroanilide |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)without inhibitor | 14 | 0.46 | 30 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 16 | 1.7 | 9.4 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 36 | 8.2 | 4.4 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 40 | 7.4 | 5.4 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 26 | 6.7 | 3.9 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 17 | 0.4 | 42 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 9.9 | 0.43 | 23 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 8 | 0.44 | 18 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| tryptase (human lung tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide)apparent kcat; apparent Km | 5 | 0.4 | 12 calc. | pH 6 | PMID 11401583 | Open record: tryptase (human lung tryptase), H-D-Ile-Pro-Arg-pNA (D-isoleucyl-prolyl-arginine p-nitroanilide) |
| β-tryptase | Homo sapiens | Ac-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | 140.7 | 0.0498 | 2822 | PMID 18320560 | Open record: β-tryptase, Ac-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | |
| β-tryptase | Homo sapiens | Ac-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | 367.2 | 0.06165 | 5956 | PMID 18320560 | Open record: β-tryptase, Ac-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | |
| β-tryptase | Homo sapiens | Ac-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | 378 | 0.07103 | 5321 | PMID 18320560 | Open record: β-tryptase, Ac-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus; Ac = N-terminal acetyl | |
| β-tryptase | Homo sapiens | Ala-Ala-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | 187.0 | 0.03944 | 4746 | PMID 18320560 | Open record: β-tryptase, Ala-Ala-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | |
| β-tryptase | Homo sapiens | Ala-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | 233.4 | 0.053 | 4403 | PMID 18320560 | Open record: β-tryptase, Ala-Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | |
| β-tryptase | Homo sapiens | Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | 158.6 | 0.0999 | 1587 | PMID 18320560 | Open record: β-tryptase, Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | |
| β-tryptase | Homo sapiens | Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | 199.4 | 0.1111 | 1795 | PMID 18320560 | Open record: β-tryptase, Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | |
| β-tryptase | Homo sapiens | Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | 435.2 | 0.04375 | 9953 | PMID 18320560 | Open record: β-tryptase, Pro-Ile-Arg-Asn-Lys-ANB-NH2, ANB-NH2 = amide of 5-amino-2-nitrobenzoic acid attached at the C-terminus | |
| β-tryptase (βI-tryptase) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 87 | 0.47 | 180 | pH 8 | PMID 29661938 | Open record: β-tryptase (βI-tryptase), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 50 | 0.82 | 61 | pH 8 | PMID 29661938 | Open record: β-tryptase (βI-tryptase) variant I99C, H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C/Y75A/Y37bA (I99C*: Cys-99 cysteinylated, monomer) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 6.7 | 1.6 | 4 | pH 8 | PMID 29661938 | Open record: β-tryptase (βI-tryptase) variant I99C/Y75A/Y37bA (I99C*: Cys-99 cysteinylated, monomer), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant I99C/Y75A/Y37bA (disulfide-linked dimer) | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 5.8 | — | — | pH 8 | PMID 29661938 | Open record: β-tryptase (βI-tryptase) variant I99C/Y75A/Y37bA (disulfide-linked dimer), H-D-Ile-Pro-Arg-p-nitroanilide |
| β-tryptase (βI-tryptase)variant Y75C | Homo sapiens | H-D-Ile-Pro-Arg-p-nitroanilide | 37 | 0.32 | 120 | pH 8 | PMID 29661938 | Open record: β-tryptase (βI-tryptase) variant Y75C, H-D-Ile-Pro-Arg-p-nitroanilide |
| βII tryptase | Homo sapiens | N-acetyl-Pro-Ala-Asn-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Ala-Asn-Lys-ACC) | 20.27 | 0.1105 | 180 | pH 7.5, 30 °C | PMID 11438529 | Open record: βII tryptase, N-acetyl-Pro-Ala-Asn-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Ala-Asn-Lys-ACC) |
| βII tryptase | Homo sapiens | N-acetyl-Pro-Arg-Asn-Arg-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Asn-Arg-ACC) | 21.75 | 0.0165 | 1.31 × 10³ | pH 7.5, 30 °C | PMID 11438529 | Open record: βII tryptase, N-acetyl-Pro-Arg-Asn-Arg-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Asn-Arg-ACC) |
| βII tryptase | Homo sapiens | N-acetyl-Pro-Arg-Asn-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Asn-Lys-ACC) | 16.84 | 0.0089 | 1.89 × 10³ | pH 7.5, 30 °C | PMID 11438529 | Open record: βII tryptase, N-acetyl-Pro-Arg-Asn-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Asn-Lys-ACC) |
| βII tryptase | Homo sapiens | N-acetyl-Pro-Arg-Thr-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Thr-Lys-ACC) | 18.67 | 0.0147 | 1.27 × 10³ | pH 7.5, 30 °C | PMID 11438529 | Open record: βII tryptase, N-acetyl-Pro-Arg-Thr-Lys-7-amino-4-carbamoylmethylcoumarin (Ac-Pro-Arg-Thr-Lys-ACC) |