Values CatLog read from this paper
A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity
PMID 17344335doi:10.1124/dmd.107.014779Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 8 records (16 values) from this paper: CBR1 I88, CBR1 V88 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 8 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
EC 1.1.1.71, EC 1.1.1.184, EC 1.1.1.189, EC 1.1.1.196, EC 1.1.1.197
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CBR1 I88 | Homo sapiens | daunorubicin | 61 | 0.14 | 440 calc. | pH 7.4, 37 °C | Open record: CBR1 I88, daunorubicin |
| CBR1 I88 | Homo sapiens | menadione | 85 | 0.055 | 1.5 × 10³ calc. | pH 7.4, 37 °C | Open record: CBR1 I88, menadione |
| CBR1 I88 | Homo sapiens | NADPH | 149 | 0.343 | 434 calc. | pH 7.4, 37 °C | Open record: CBR1 I88, NADPH |
| CBR1 I88 | Homo sapiens | prostaglandin E2 | 18 | 0.32 | 56 calc. | pH 7.4, 37 °C | Open record: CBR1 I88, prostaglandin E2 |
| CBR1 V88 | Homo sapiens | daunorubicin | 91 | 0.173 | 530 calc. | pH 7.4, 37 °C | Open record: CBR1 V88, daunorubicin |
| CBR1 V88 | Homo sapiens | menadione | 110 | 0.042 | 2.6 × 10³ calc. | pH 7.4, 37 °C | Open record: CBR1 V88, menadione |
| CBR1 V88 | Homo sapiens | NADPH | 179 | 0.247 | 725 calc. | pH 7.4, 37 °C | Open record: CBR1 V88, NADPH |
| CBR1 V88 | Homo sapiens | prostaglandin E2 | 25 | 0.309 | 81 calc. | pH 7.4, 37 °C | Open record: CBR1 V88, prostaglandin E2 |