EC 1.1.1.71: alcohol dehydrogenase [NAD(P)+]
OxidoreductasesOpen in Browse
CatLog read 63 records for EC 1.1.1.71 from 6 papers, for 6 organisms. Names in these papers: NADP-dependent alcohol dehydrogenase, TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), AdhE (bifunctional alcohol and aldehyde dehydrogenase), carbonyl reductase 1 (hCBR1) and 4 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 58 records for EC 1.1.1.71 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.71 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| NADP-dependent alcohol dehydrogenases in bacteria and yeast: purification and partial characterization of the enzymes from Acinetobacter calcoaceticus and Saccharomyces cerevisiae | Acinetobacter calcoaceticus, Pseudomonas aeruginosa and 1 more | 34 |
| Sodium chloride-induced modulation of the activity and thermal stability of short-chain oxidoreductase from the archaeon Thermococcus sibiricus | Thermococcus sibiricus | 12 |
| A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity | Homo sapiens | 8 |
| Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1 | Homo sapiens | 4 |
| Cofactor Specificity of the Bifunctional Alcohol and Aldehyde Dehydrogenase (AdhE) in Wild-Type and Mutant Clostridium thermocellum and Thermoanaerobacterium saccharolyticum | Clostridium thermocellum | 4 |
| Human carbonyl reductase 1 is an S-nitrosoglutathione reductase | Homo sapiens | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| AdhE (bifunctional alcohol and aldehyde dehydrogenase)variant D494G (LL350) | Clostridium thermocellum | Acetaldehydecosubstrate NADH | 220 | 1.4 | 150 | 55 °C | PMID 26013492 | Open record: AdhE (bifunctional alcohol and aldehyde dehydrogenase) variant D494G (LL350), Acetaldehyde |
| AdhE (bifunctional alcohol and aldehyde dehydrogenase)variant D494G (LL350) | Clostridium thermocellum | Acetaldehydecosubstrate NADPH | 210 | 1.4 | 150 | 55 °C | PMID 26013492 | Open record: AdhE (bifunctional alcohol and aldehyde dehydrogenase) variant D494G (LL350), Acetaldehyde |
| AdhE (bifunctional alcohol and aldehyde dehydrogenase)variant D494G (LL350) | Clostridium thermocellum | NADH | 220 | 0.17 | 1.3 × 10³ | 55 °C | PMID 26013492 | Open record: AdhE (bifunctional alcohol and aldehyde dehydrogenase) variant D494G (LL350), NADH |
| AdhE (bifunctional alcohol and aldehyde dehydrogenase)variant D494G (LL350) | Clostridium thermocellum | NADPH | 280 | 0.075 | 3.7 × 10³ | 55 °C | PMID 26013492 | Open record: AdhE (bifunctional alcohol and aldehyde dehydrogenase) variant D494G (LL350), NADPH |
| carbonyl reductase 1 (hCBR1) | Homo sapiens | 4-benzoylpyridine | 6.7 | 0.36 | 18 | pH 6.5, 25 °C | PMID 18493841 | Open record: carbonyl reductase 1 (hCBR1), 4-benzoylpyridine |
| carbonyl reductase 1 (hCBR1) | Homo sapiens | 4-nitrobenzaldehyde | 3.2 | 1.3 | 2.5 | pH 6.5, 25 °C | PMID 18493841 | Open record: carbonyl reductase 1 (hCBR1), 4-nitrobenzaldehyde |
| carbonyl reductase 1 (hCBR1) | Homo sapiens | menadione (2-methyl-1,4-naphthoquinone) | 7.3 | 0.028 | 270 | pH 6.5, 25 °C | PMID 18493841 | Open record: carbonyl reductase 1 (hCBR1), menadione (2-methyl-1,4-naphthoquinone) |
| carbonyl reductase 1 (hCBR1) | Homo sapiens | NADPH | — | 0.0062 | — | pH 6.5, 25 °C | PMID 18493841 | Open record: carbonyl reductase 1 (hCBR1), NADPH |
| CBR1 I88 | Homo sapiens | daunorubicin | 61 | 0.14 | 440 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 I88, daunorubicin |
| CBR1 I88 | Homo sapiens | menadione | 85 | 0.055 | 1.5 × 10³ calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 I88, menadione |
| CBR1 I88 | Homo sapiens | NADPH | 149 | 0.343 | 434 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 I88, NADPH |
| CBR1 I88 | Homo sapiens | prostaglandin E2 | 18 | 0.32 | 56 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 I88, prostaglandin E2 |
| CBR1 V88 | Homo sapiens | daunorubicin | 91 | 0.173 | 530 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 V88, daunorubicin |
| CBR1 V88 | Homo sapiens | menadione | 110 | 0.042 | 2.6 × 10³ calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 V88, menadione |
| CBR1 V88 | Homo sapiens | NADPH | 179 | 0.247 | 725 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 V88, NADPH |
| CBR1 V88 | Homo sapiens | prostaglandin E2 | 25 | 0.309 | 81 calc. | pH 7.4, 37 °C | PMID 17344335 | Open record: CBR1 V88, prostaglandin E2 |
| human carbonyl reductase 1 (hCBR1) | Homo sapiens | S-nitrosoglutathione | 7.5 | 0.0301 | 249.2 | pH 6.8 | PMID 18826943 | Open record: human carbonyl reductase 1 (hCBR1), S-nitrosoglutathione |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Benzyl alcohol | — | 15 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Benzyl alcohol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Butan-1-olapparent Km | — | 52.7 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Butan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 38.3 | — | 0.726 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Butanalapparent Km | — | 3.97 | — | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butanal |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Butanalapparent kcat; kcat per active site; apparent kcat/Km | 26.3 | — | 6.62 | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butanal |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Ethanolapparent Km | — | 727 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Ethanol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Ethanolapparent kcat; kcat per active site; apparent kcat/Km | 13.9 | — | 0.019 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Ethanol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Heptan-1-olapparent Km | — | 1.09 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Heptan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Heptan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 38.9 | — | 35.7 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Heptan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Hexan-1-olapparent Km | — | 1.22 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Hexan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Hexan-1-ol | — | 12.1 | — | pH 7.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Hexan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Hexan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 39.4 | — | 32.3 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Hexan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | NADP+ | — | 0.038 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, NADP+ |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | NADPH | — | 0.00433 | — | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, NADPH |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Octan-1-olapparent Km | — | 1.1 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Octan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Octan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 25.4 | — | 23.1 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Octan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Pentan-1-olapparent Km | — | 5.8 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Pentan-1-ol |
| NADP-dependent alcohol dehydrogenase | Acinetobacter calcoaceticus | Pentan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 44.7 | — | 7.71 | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Pentan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Butan-1-olapparent Km | — | 78.6 | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Butan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 50.6 | — | 0.64 | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Butanalapparent Km | — | 0.75 | — | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butanal |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Butanalapparent kcat; kcat per active site; apparent kcat/Km | 19.6 | — | 26 | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Butanal |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Ethanolapparent Km | — | 4.79 × 10³ | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Ethanol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Ethanolapparent kcat; kcat per active site; apparent kcat/Km | 35.1 | — | 0.0073 | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Ethanol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Hexan-1-olapparent Km | — | 6.8 | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Hexan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Hexan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 40.3 | — | 5.8 | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Hexan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | NADP+ | — | 0.0202 | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, NADP+ |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | NADPH | — | 7.9 × 10⁻⁴ | — | pH 6.8, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, NADPH |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Octan-1-olapparent Km | — | 6.2 | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Octan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Octan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 39.8 | — | 6.4 | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Octan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Pentan-1-olapparent Km | — | 14.1 | — | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Pentan-1-ol |
| NADP-dependent alcohol dehydrogenase | Saccharomyces cerevisiae | Pentan-1-olapparent kcat; kcat per active site; apparent kcat/Km | 62.9 | — | 4.5 | pH 10.7, 27 °C | PMID 8162187 | Open record: NADP-dependent alcohol dehydrogenase, Pentan-1-ol |
| NADP-dependent hexan-1-ol dehydrogenase | Acinetobacter calcoaceticus | Hexan-1-ol | — | 1.16 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent hexan-1-ol dehydrogenase, Hexan-1-ol |
| NADP-dependent hexan-1-ol dehydrogenase | Pseudomonas aeruginosa | Hexan-1-ol | — | 1.11 | — | pH 10.2, 27 °C | PMID 8162187 | Open record: NADP-dependent hexan-1-ol dehydrogenase, Hexan-1-ol |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | 2-oxopropanalno added NaCl | 2.04 | 17.75 | 0.11 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), 2-oxopropanal |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | 2-oxopropanalwith 1 M NaCl in buffer (Table 1 footnote c) | 4.03 | 14.43 | 0.28 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), 2-oxopropanal |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | hexane-2,5-diolno added NaCl | 2.2 | 13.1 | 0.17 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), hexane-2,5-diol |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | hexane-2,5-diolwith 1 M NaCl in buffer (Table 1 footnote c) | 6.9 | 17 | 0.41 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), hexane-2,5-diol |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | NADP+no added NaCl | 2.02 | 0.02 | 101 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), NADP+ |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | NADP+with 1 M NaCl in buffer (Table 1 footnote c) | 6.88 | 0.08 | 86 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), NADP+ |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | NADPHno added NaCl | 1.51 | 0.02 | 76 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), NADPH |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | NADPHwith 1 M NaCl in buffer (Table 1 footnote c) | 7.46 | 0.146 | 51 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), NADPH |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | pentane-2,3-dioneno added NaCl | 1.4 | 1.05 | 1.33 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), pentane-2,3-dione |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | pentane-2,3-dionewith 1 M NaCl in buffer (Table 1 footnote c) | 4.74 | 2.2 | 2.15 | pH 7.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), pentane-2,3-dione |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | propan-2-olno added NaCl | 0.53 | 168 | 0.0032 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), propan-2-ol |
| TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase) | Thermococcus sibiricus | propan-2-olwith 1 M NaCl in buffer (Table 1 footnote c) | 1.64 | 591 | 0.0028 | pH 10.5, 60 °C | PMID 24061874 | Open record: TsAdh319 (short-chain NADP(H)-dependent alcohol dehydrogenase), propan-2-ol |