Values CatLog read from this paper
Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase
PMID 22289630doi:10.1016/j.bbapap.2012.01.007Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 18 records (24 values) from this paper: adenylosuccinate synthetase (PfAdSS) from Plasmodium falciparum.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 6 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| adenylosuccinate synthetase (PfAdSS) | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.0248 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS), guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS) | Plasmodium falciparum | inosine 5'-monophosphate | 1.1 | 0.0168 | 65 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS), inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS) | Plasmodium falciparum | L-aspartate | — | 1.9 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS), L-aspartate |
| adenylosuccinate synthetase (PfAdSS)variant C328D | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.0251 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328D | Plasmodium falciparum | inosine 5'-monophosphate | 1.7 | 0.0276 | 62 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328D | Plasmodium falciparum | L-aspartate | — | 1.4 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, L-aspartate |
| adenylosuccinate synthetase (PfAdSS)variant C328D/C368D | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.0358 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328D/C368D | Plasmodium falciparum | inosine 5'-monophosphate | 0.7 | 0.0292 | 24 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328D/C368D | Plasmodium falciparum | L-aspartate | — | 1.73 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, L-aspartate |
| adenylosuccinate synthetase (PfAdSS)variant C328S | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.044 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328S | Plasmodium falciparum | inosine 5'-monophosphate | 0.84 | 0.0152 | 55 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328S | Plasmodium falciparum | L-aspartate | — | 1.9 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, L-aspartate |
| adenylosuccinate synthetase (PfAdSS)variant C328S/C368S | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.0172 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328S/C368S | Plasmodium falciparum | inosine 5'-monophosphate | 0.62 | 0.0198 | 31 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS)variant C328S/C368S | Plasmodium falciparum | L-aspartate | — | 0.49 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, L-aspartate |
| adenylosuccinate synthetase (PfAdSS)variant C368S | Plasmodium falciparum | guanosine 5'-triphosphate | — | 0.0206 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, guanosine 5'-triphosphate |
| adenylosuccinate synthetase (PfAdSS)variant C368S | Plasmodium falciparum | inosine 5'-monophosphate | 1 | 0.0248 | 40 calc. | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, inosine 5'-monophosphate |
| adenylosuccinate synthetase (PfAdSS)variant C368S | Plasmodium falciparum | L-aspartate | — | 3.3 | — | pH 7.4, 25 °C | Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, L-aspartate |