EC 6.3.4.4: adenylosuccinate synthase

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CatLog read 128 records for EC 6.3.4.4 from 6 papers, for 3 organisms. Names in these papers: adenylosuccinate synthetase, adenylosuccinate synthetase (PfAdSS), adenylosuccinate synthetase, basic (muscle) isozyme.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 162 records for EC 6.3.4.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.4.4 in Browse.

Papers

Papers with records for EC 6.3.4.4
Paper	Organisms	Records
Determinants of L-aspartate and IMP recognition in Escherichia coli adenylosuccinate synthetase	Escherichia coli	36
Ambiguities in mapping the active site of a conformationally dynamic enzyme by directed mutation. Role of dynamics in structure-function correlations in Escherichia coli adenylosuccinate synthetase	Escherichia coli	28
Studies on active site mutants of P. falciparum adenylosuccinate synthetase: insights into enzyme catalysis and activation	Plasmodium falciparum	22
Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase	Plasmodium falciparum	18
Residues essential for catalysis and stability of the active site of Escherichia coli adenylosuccinate synthetase as revealed by directed mutation and kinetics	Escherichia coli	18
Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases	Escherichia coli, Mus musculus	6

Records

Records for EC 6.3.4.4 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
adenylosuccinate synthetase	Escherichia coli	2′-deoxyinosine 5′-monophosphate	0.96	0.041	23 calc.	pH 7.7, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, 2′-deoxyinosine 5′-monophosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5'-triphosphate	—	0.022	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, guanosine 5'-triphosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5'-triphosphate	—	0.013	—	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, guanosine 5'-triphosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5'-triphosphate	—	0.026	38	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, guanosine 5'-triphosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5'-triphosphate	—	0.011	9	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, guanosine 5'-triphosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5'-triphosphate	—	0.19	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase, guanosine 5'-triphosphate
adenylosuccinate synthetase	Escherichia coli	guanosine 5′-triphosphate	—	0.021	—	pH 7.7, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, guanosine 5′-triphosphate
adenylosuccinate synthetase	Escherichia coli	hydroxylamine	0.5	230	0.0022 calc.	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase, hydroxylamine
adenylosuccinate synthetase	Escherichia coli	inosine 5'-monophosphate	—	0.021	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, inosine 5'-monophosphate
adenylosuccinate synthetase	Escherichia coli	inosine 5'-monophosphate	—	0.0131	—	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, inosine 5'-monophosphate
adenylosuccinate synthetase	Escherichia coli	inosine 5'-monophosphate	1	0.028	36	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, inosine 5'-monophosphate
adenylosuccinate synthetase	Escherichia coli	inosine 5'-monophosphate	0.096	0.07	1.4	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, inosine 5'-monophosphate
adenylosuccinate synthetase	Escherichia coli	inosine 5'-monophosphate	—	0.066	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase, inosine 5'-monophosphate
adenylosuccinate synthetase	Escherichia coli	L-aspartate	1.37	0.28	4.9 calc.	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, L-aspartate
adenylosuccinate synthetase	Escherichia coli	L-aspartate	1.92	0.228	8.42 calc.	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase, L-aspartate
adenylosuccinate synthetase	Escherichia coli	L-aspartate	—	0.23	4.4	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, L-aspartate
adenylosuccinate synthetase	Escherichia coli	L-aspartate	—	0.9	0.11	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase, L-aspartate
adenylosuccinate synthetase	Escherichia coli	L-aspartate	—	13	—	pH 7.7, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, L-aspartate
adenylosuccinate synthetasevariant D21A	Escherichia coli	guanosine 5'-triphosphate	—	0.052	0.95	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant D21A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant D21A	Escherichia coli	inosine 5'-monophosphate	0.049	0.048	1.02	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant D21A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant D21A	Escherichia coli	L-aspartate	—	0.17	0.3	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant D21A, L-aspartate
adenylosuccinate synthetasevariant E14A	Escherichia coli	guanosine 5'-triphosphate	—	0.031	—	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant E14A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant E14A	Escherichia coli	inosine 5'-monophosphate	—	0.055	—	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant E14A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant E14A	Escherichia coli	L-aspartate	0.022	1.4	0.016 calc.	pH 7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant E14A, L-aspartate
adenylosuccinate synthetasevariant H41N	Escherichia coli	guanosine 5'-triphosphate	—	0.126	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant H41N, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant H41N	Escherichia coli	inosine 5'-monophosphate	—	0.0401	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant H41N, inosine 5'-monophosphate
adenylosuccinate synthetasevariant H41N	Escherichia coli	L-aspartate	0.00951	1.95	0.00488 calc.	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant H41N, L-aspartate
adenylosuccinate synthetasevariant K16Q	Escherichia coli	guanosine 5'-triphosphate	—	0.023	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant K16Q, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant K16Q	Escherichia coli	inosine 5'-monophosphate	—	0.0505	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant K16Q, inosine 5'-monophosphate
adenylosuccinate synthetasevariant K16Q	Escherichia coli	L-aspartate	0.479	0.308	1.56 calc.	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant K16Q, L-aspartate
adenylosuccinate synthetasevariant N38A	Escherichia coli	guanosine 5'-triphosphate	—	0.041	0.12	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant N38A	Escherichia coli	inosine 5'-monophosphate	0.0048	0.049	0.1	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant N38A	Escherichia coli	L-aspartate	—	0.3	0.016	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38A, L-aspartate
adenylosuccinate synthetasevariant N38D	Escherichia coli	guanosine 5'-triphosphate	—	0.27	0.051	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant N38D	Escherichia coli	guanosine 5'-triphosphate	—	0.116	1.5	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant N38D	Escherichia coli	inosine 5'-monophosphate	0.0134	1.6	0.008	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, inosine 5'-monophosphate
adenylosuccinate synthetasevariant N38D	Escherichia coli	inosine 5'-monophosphatespectrophotometric assay; absorbance at 290 nm	0.171	3.8	0.045	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, inosine 5'-monophosphate
adenylosuccinate synthetasevariant N38D	Escherichia coli	inosine 5'-monophosphatekcat-vs-pH profile (Figure 3); 20 mM MES/HEPES buffer	0.237	—	—	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, inosine 5'-monophosphate
adenylosuccinate synthetasevariant N38D	Escherichia coli	L-aspartate	—	2.6	0.0052	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, L-aspartate
adenylosuccinate synthetasevariant N38D	Escherichia coli	L-aspartate	—	0.5	0.33	pH 5.6, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38D, L-aspartate
adenylosuccinate synthetasevariant N38E	Escherichia coli	guanosine 5'-triphosphate	—	0.054	0.62	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38E, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant N38E	Escherichia coli	inosine 5'-monophosphate	0.034	0.028	1.22	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38E, inosine 5'-monophosphate
adenylosuccinate synthetasevariant N38E	Escherichia coli	L-aspartate	—	0.24	0.143	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant N38E, L-aspartate
adenylosuccinate synthetasevariant R131L	Escherichia coli	guanosine 5'-triphosphate	—	0.0352	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant R131L, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant R131L	Escherichia coli	inosine 5'-monophosphate	—	0.0355	—	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant R131L, inosine 5'-monophosphate
adenylosuccinate synthetasevariant R131L	Escherichia coli	L-aspartate	1.41	1	1.4 calc.	pH 7.7, 25 °C	PMID 9115248	Open record: adenylosuccinate synthetase variant R131L, L-aspartate
adenylosuccinate synthetasevariant R419L	Escherichia coli	guanosine 5'-triphosphate	—	0.25	0.41	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant R419L, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant R419L	Escherichia coli	inosine 5'-monophosphate	0.1	0.2	0.49	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant R419L, inosine 5'-monophosphate
adenylosuccinate synthetasevariant R419L	Escherichia coli	L-aspartate	—	0.34	0.29	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant R419L, L-aspartate
adenylosuccinate synthetasevariant T128A	Escherichia coli	guanosine 5'-triphosphate	—	0.054	9	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T128A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T128A	Escherichia coli	inosine 5'-monophosphate	—	0.31	1.5	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T128A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T128A	Escherichia coli	L-aspartate	0.46	0.17	2.7	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T128A, L-aspartate
adenylosuccinate synthetasevariant T129A	Escherichia coli	guanosine 5'-triphosphate	—	1.7	0.25	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T129A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T129A	Escherichia coli	inosine 5'-monophosphate	—	0.89	0.47	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T129A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T129A	Escherichia coli	L-aspartate	0.42	0.24	1.75	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T129A, L-aspartate
adenylosuccinate synthetasevariant T300A	Escherichia coli	guanosine 5'-triphosphate	—	0.17	3.9	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T300A	Escherichia coli	inosine 5'-monophosphate	—	0.019	34	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T300A	Escherichia coli	L-aspartate	0.64	6.2	0.1	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300A, L-aspartate
adenylosuccinate synthetasevariant T300V	Escherichia coli	guanosine 5'-triphosphate	—	0.056	60	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300V, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T300V	Escherichia coli	inosine 5'-monophosphate	—	0.033	100	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300V, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T300V	Escherichia coli	L-aspartate	3.3	0.82	4.1	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T300V, L-aspartate
adenylosuccinate synthetasevariant T301A	Escherichia coli	guanosine 5'-triphosphate	—	0.057	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T301A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T301A	Escherichia coli	hydroxylamine	0.24	91	0.0026 calc.	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T301A, hydroxylamine
adenylosuccinate synthetasevariant T301A	Escherichia coli	inosine 5'-monophosphate	—	0.32	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant T301A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T42A	Escherichia coli	guanosine 5'-triphosphate	—	0.28	3.2	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant T42A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant T42A	Escherichia coli	inosine 5'-monophosphate	0.89	0.123	7.2	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant T42A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant T42A	Escherichia coli	L-aspartate	—	1.4	0.65	pH 7.7, 25 °C	PMID 9632649	Open record: adenylosuccinate synthetase variant T42A, L-aspartate
adenylosuccinate synthetasevariant V273A	Escherichia coli	guanosine 5'-triphosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.031	32	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273A	Escherichia coli	guanosine 5'-triphosphatemagnesium chloride; UV difference assay at 280 nm	—	0.14	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273A	Escherichia coli	hydroxylamine	0.21	255	8.2 × 10⁻⁴ calc.	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, hydroxylamine
adenylosuccinate synthetasevariant V273A	Escherichia coli	inosine 5'-monophosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.017	59	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273A	Escherichia coli	inosine 5'-monophosphatemagnesium chloride; UV difference assay at 280 nm	—	0.14	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273A	Escherichia coli	L-aspartate	1	7	0.14	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273A, L-aspartate
adenylosuccinate synthetasevariant V273N	Escherichia coli	guanosine 5'-triphosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.021	2.4	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273N	Escherichia coli	guanosine 5'-triphosphatemagnesium chloride; UV difference assay at 280 nm	—	0.18	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273N	Escherichia coli	hydroxylamine	0.29	110	0.0026 calc.	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, hydroxylamine
adenylosuccinate synthetasevariant V273N	Escherichia coli	inosine 5'-monophosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.024	2.1	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273N	Escherichia coli	inosine 5'-monophosphatemagnesium chloride; UV difference assay at 280 nm	—	0.113	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273N	Escherichia coli	L-aspartate	0.05	9	0.006	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273N, L-aspartate
adenylosuccinate synthetasevariant V273T	Escherichia coli	guanosine 5'-triphosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.045	44	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273T	Escherichia coli	guanosine 5'-triphosphatemagnesium chloride; UV difference assay at 280 nm	—	0.074	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, guanosine 5'-triphosphate
adenylosuccinate synthetasevariant V273T	Escherichia coli	hydroxylamine	0.08	140	5.7 × 10⁻⁴ calc.	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, hydroxylamine
adenylosuccinate synthetasevariant V273T	Escherichia coli	inosine 5'-monophosphateL-aspartate reaction: 20 mM Hepes pH 7.7	—	0.043	46	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273T	Escherichia coli	inosine 5'-monophosphatemagnesium chloride; UV difference assay at 280 nm	—	0.077	—	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, inosine 5'-monophosphate
adenylosuccinate synthetasevariant V273T	Escherichia coli	L-aspartate	1.99	3.4	0.61	pH 7.7, 25 °C	PMID 11781326	Open record: adenylosuccinate synthetase variant V273T, L-aspartate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.02477	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.02714	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.0248	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS), guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	inosine 5'-monophosphate	1.44	0.01677	85.9 calc.	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	inosine 5'-monophosphate	0.9987	0.0205	48.7 calc.	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	inosine 5'-monophosphate	1.1	0.0168	65 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS), inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	L-aspartate	—	0.31	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), L-aspartate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	L-aspartate	—	0.37	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS), L-aspartate
adenylosuccinate synthetase (PfAdSS)	Plasmodium falciparum	L-aspartate	—	1.9	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS), L-aspartate
adenylosuccinate synthetase (PfAdSS)variant C328D	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.0251	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant C328D	Plasmodium falciparum	inosine 5'-monophosphate	1.7	0.0276	62 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant C328D	Plasmodium falciparum	L-aspartate	—	1.4	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant C328D/C368D	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.0358	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant C328D/C368D	Plasmodium falciparum	inosine 5'-monophosphate	0.7	0.0292	24 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant C328D/C368D	Plasmodium falciparum	L-aspartate	—	1.73	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328D/C368D, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant C328S	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.044	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant C328S	Plasmodium falciparum	inosine 5'-monophosphate	0.84	0.0152	55 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant C328S	Plasmodium falciparum	L-aspartate	—	1.9	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant C328S/C368S	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.0172	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant C328S/C368S	Plasmodium falciparum	inosine 5'-monophosphate	0.62	0.0198	31 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant C328S/C368S	Plasmodium falciparum	L-aspartate	—	0.49	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C328S/C368S, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant C368S	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.0206	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant C368S	Plasmodium falciparum	inosine 5'-monophosphate	1	0.0248	40 calc.	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant C368S	Plasmodium falciparum	L-aspartate	—	3.3	—	pH 7.4, 25 °C	PMID 22289630	Open record: adenylosuccinate synthetase (PfAdSS) variant C368S, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant K62L	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.04646	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant K62L, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant K62L	Plasmodium falciparum	inosine 5'-monophosphate	1.09	0.02161	50.4 calc.	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant K62L, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant K62L	Plasmodium falciparum	L-aspartate	—	0.78	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant K62L, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant N429V	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.02705	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant N429V, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant N429V	Plasmodium falciparum	inosine 5'-monophosphate	0.32	0.04966	6.4 calc.	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant N429V, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant N429V	Plasmodium falciparum	L-aspartate	—	0.57	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant N429V, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant R155A	Plasmodium falciparum	inosine 5'-monophosphate	0.0063	—	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155A, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant R155K	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.03857	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155K, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant R155K	Plasmodium falciparum	inosine 5'-monophosphate	0.1162	0.5574	0.2080 calc.	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155K, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant R155K	Plasmodium falciparum	L-aspartate	—	0.48	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155K, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant R155L	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.02785	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155L, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant R155L	Plasmodium falciparum	inosine 5'-monophosphate	0.0103	2.554	0.00400 calc.	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155L, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant R155L	Plasmodium falciparum	L-aspartate	—	1.32	—	pH 7, 25 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant R155L, L-aspartate
adenylosuccinate synthetase (PfAdSS)variant T307V	Plasmodium falciparum	guanosine 5'-triphosphate	—	0.03474	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant T307V, guanosine 5'-triphosphate
adenylosuccinate synthetase (PfAdSS)variant T307V	Plasmodium falciparum	inosine 5'-monophosphate	1.72	0.02849	60.4 calc.	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant T307V, inosine 5'-monophosphate
adenylosuccinate synthetase (PfAdSS)variant T307V	Plasmodium falciparum	L-aspartate	—	1.1	—	pH 7, 37 °C	PMID 20654742	Open record: adenylosuccinate synthetase (PfAdSS) variant T307V, L-aspartate
adenylosuccinate synthetase, basic (muscle) isozyme	Mus musculus	2′-deoxyinosine 5′-monophosphate	5.5	0.058	95 calc.	pH 7.2, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, basic (muscle) isozyme, 2′-deoxyinosine 5′-monophosphate
adenylosuccinate synthetase, basic (muscle) isozyme	Mus musculus	guanosine 5′-triphosphate	—	0.015	—	pH 7.2, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, basic (muscle) isozyme, guanosine 5′-triphosphate
adenylosuccinate synthetase, basic (muscle) isozyme	Mus musculus	L-aspartate	—	4	—	pH 7.2, 22 °C	PMID 16981730	Open record: adenylosuccinate synthetase, basic (muscle) isozyme, L-aspartate