Values CatLog read from this paper
Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase
PMID 39615689doi:10.1016/j.jbc.2024.108039Open in Browse
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CatLog read 12 records (26 values) from this paper: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) from Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Ala-Arg-Arg-Gln-Ala-Gly-Thr-Arg-Arg-Arg-Glu-Ser-Leu-Gly-Lys | 13.4 | 0.0299 | 400 | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Ala-Arg-Arg-Gln-Ala-Gly-Thr-Arg-Arg-Arg-Glu-Ser-Leu-Gly-Lys |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Ca_V1.3 EF-hand and PreIQ domain construct, residues 1468-1598 (site Ser1475, = Ser1535 in Ca_V1.2), with N-terminal SNA cloning artefact | 1.3 | — | — | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Ca_V1.3 EF-hand and PreIQ domain construct, residues 1468-1598 (site Ser1475, = Ser1535 in Ca_V1.2), with N-terminal SNA cloning artefact |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Gly-Ala-Gly-Arg-Glu-Arg-Asp-Arg-Arg-Arg-Gly-Ser-Thr-Pro-Trp | 16.2 | 0.019 | 900 | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Gly-Ala-Gly-Arg-Glu-Arg-Asp-Arg-Arg-Arg-Gly-Ser-Thr-Pro-Trp |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Leu-Arg-Arg-Ala-Ser-Leu-Gly | 19 | 0.0426 | 470 | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Leu-Arg-Arg-Ala-Ser-Leu-Gly |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RGFARSASLGRRASFHL (human Ca_V1.2 residues 1968-1984, L1971A) | 19.7 | 0.0097 | 2 × 10³ | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RGFARSASLGRRASFHL (human Ca_V1.2 residues 1968-1984, L1971A) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RGFLRSARLGRRASFHL (human Ca_V1.2 residues 1968-1984, S1975R) | 7.5 | 0.0062 | 1.2 × 10³ | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RGFLRSARLGRRASFHL (human Ca_V1.2 residues 1968-1984, S1975R) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RGFLRSASLGRAASFHL (human Ca_V1.2 residues 1968-1984, R1979A) | 1.1 | — | — | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RGFLRSASLGRAASFHL (human Ca_V1.2 residues 1968-1984, R1979A) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RGFLRSASLGRRASAHL (human Ca_V1.2 residues 1968-1984, F1982A) | 13.1 | 0.0096 | 1.4 × 10³ | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RGFLRSASLGRRASAHL (human Ca_V1.2 residues 1968-1984, F1982A) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RGFLRSASLGRRASFHL (human Ca_V1.2 residues 1968-1984) | 15.5 | 0.0081 | 1.9 × 10³ | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RGFLRSASLGRRASFHL (human Ca_V1.2 residues 1968-1984) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | peptide RTLHDIGPEIRRAISGDL (human Ca_V1.2 residues 1704-1721) | 3.4 | — | — | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), peptide RTLHDIGPEIRRAISGDL (human Ca_V1.2 residues 1704-1721) |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Ser-Arg-Lys-Met-Ala-Phe-Arg-Ala-Lys-Ser-Lys-Ser-Cys-His-Asp | 3.3 | — | — | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Ser-Arg-Lys-Met-Ala-Phe-Arg-Ala-Lys-Ser-Lys-Ser-Cys-His-Asp |
| PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα) | Mus musculus | Trp-Gly-Pro-Ala-Pro-Pro-Leu-His-Arg-Arg-Ser-Met-Pro | 2 | — | — | pH 7.4 | Open record: PKAc (cAMP-dependent protein kinase catalytic subunit, isoform alpha; PKAcα), Trp-Gly-Pro-Ala-Pro-Pro-Leu-His-Arg-Arg-Ser-Met-Pro |