Values CatLog read from this paper

Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure

PMID 16361254doi:10.1074/jbc.m509822200Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 10 records (30 values) from this paper: tRNase Z^L (long form, ELAC2), tRNase Z^S (short form, ELAC1) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.

EC 3.1.26.11

Records read from this paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Open record
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7443U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.232	6.33 × 10⁻⁵	3.7 × 10³	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7443U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7444C→U substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.153	6.9 × 10⁻⁶	2.12 × 10⁴	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7444C→U substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.0127	1.97 × 10⁻⁵	670	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.345	8.55 × 10⁻⁵	4 × 10³	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7510A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.048	1.08 × 10⁻⁵	5.2 × 10³	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7510A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7511A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.053	7.6 × 10⁻⁶	7.7 × 10³	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7511A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7512A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer	0.045	4 × 10⁻⁶	1.12 × 10⁴	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7512A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer
tRNase Z^L (long form, ELAC2)	Homo sapiens	human mitochondrial pre-tRNA(Ser(UCN)), wild type: 69-nt tRNA with mature 5' end and 19-nt 3' end trailer (88 nt)	0.073	4.8 × 10⁻⁶	1.68 × 10⁴	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)), wild type: 69-nt tRNA with mature 5' end and 19-nt 3' end trailer (88 nt)
tRNase Z^L (long form, ELAC2)	Homo sapiens	human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt)	6.18	2.2 × 10⁻⁵	2.67 × 10⁵	pH 6.75, 37 °C	Open record: tRNase Z^L (long form, ELAC2), human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt)
tRNase Z^S (short form, ELAC1)	Homo sapiens	human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt)	0.0207	1.32 × 10⁻⁴	162	pH 6.75, 37 °C	Open record: tRNase Z^S (short form, ELAC1), human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt)