EC 3.1.26.11: tRNase Z
HydrolasesOpen in Browse
CatLog read 28 records for EC 3.1.26.11 from 3 papers, for 5 organisms. Names in these papers: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1), tRNase Z^L (long form, ELAC2), bsu-RNase Z, mmp-RNase Z and 2 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 5 records for EC 3.1.26.11 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.26.11 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure | Homo sapiens | 10 |
| Metal requirements and phosphodiesterase activity of tRNase Z enzymes | Arabidopsis thaliana | 9 |
| Characterization of the Methanomicrobial Archaeal RNase Zs for Processing the CCA-Containing tRNA Precursors | Bacillus subtilis, Methanococcus maripaludis and 1 more | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| bsu-RNase Z | Bacillus subtilis | precursor tRNA trn62 of Bacillus subtilis 168 (genetically encoded CCA, with 3′-trailer) | 0.023 | 5.6 × 10⁻⁴ | 42 | pH 7.5, 37 °C | PMID 32982996 | Open record: bsu-RNase Z, precursor tRNA trn62 of Bacillus subtilis 168 (genetically encoded CCA, with 3′-trailer) |
| bsu-RNase Z | Bacillus subtilis | precursor tRNA trnI of Bacillus subtilis 168 (CCA-less, with 3′-trailer)no CoCl2 (no metal ion added) | 0.014 | 8.7 × 10⁻⁴ | 15.95 | pH 7.5, 37 °C | PMID 32982996 | Open record: bsu-RNase Z, precursor tRNA trnI of Bacillus subtilis 168 (CCA-less, with 3′-trailer) |
| bsu-RNase Z | Bacillus subtilis | precursor tRNA trnI of Bacillus subtilis 168 (CCA-less, with 3′-trailer)with 1 mM CoCl2 | 0.48 | 8.9 × 10⁻⁴ | 539.3 | pH 7.5, 37 °C | PMID 32982996 | Open record: bsu-RNase Z, precursor tRNA trnI of Bacillus subtilis 168 (CCA-less, with 3′-trailer) |
| mmp-RNase Z | Methanococcus maripaludis | precursor tRNA-Arg1 of Methanococcus maripaludis S2 (CCA-less, with 3′-trailer)no CoCl2 (no metal ion added) | 7.5 × 10⁻⁵ | 8.09 × 10⁻⁴ | 0.093 | pH 7.5, 37 °C | PMID 32982996 | Open record: mmp-RNase Z, precursor tRNA-Arg1 of Methanococcus maripaludis S2 (CCA-less, with 3′-trailer) |
| mmp-RNase Z | Methanococcus maripaludis | precursor tRNA-Arg1 of Methanococcus maripaludis S2 (CCA-less, with 3′-trailer)with 1 mM CoCl2 | 0.105 | 3.6 × 10⁻⁴ | 292 | pH 7.5, 37 °C | PMID 32982996 | Open record: mmp-RNase Z, precursor tRNA-Arg1 of Methanococcus maripaludis S2 (CCA-less, with 3′-trailer) |
| mmp-RNase Z | Methanococcus maripaludis | precursor tRNA-Arg2 of Methanococcus maripaludis S2 (genetically encoded CCA, with 3′-trailer) | 0.225 | 2.5 × 10⁻⁴ | 900 | pH 7.5, 37 °C | PMID 32982996 | Open record: mmp-RNase Z, precursor tRNA-Arg2 of Methanococcus maripaludis S2 (genetically encoded CCA, with 3′-trailer) |
| mpy-RNase Z | Methanolobus psychrophilus | precursor tRNA-Arg1 of Methanolobus psychrophilus R15 (CCA-less, with 3′-trailer)no CoCl2 (no metal ion added) | 2.38 × 10⁻⁴ | 6 × 10⁻⁴ | 0.4 | pH 7.5, 37 °C | PMID 32982996 | Open record: mpy-RNase Z, precursor tRNA-Arg1 of Methanolobus psychrophilus R15 (CCA-less, with 3′-trailer) |
| mpy-RNase Z | Methanolobus psychrophilus | precursor tRNA-Arg1 of Methanolobus psychrophilus R15 (CCA-less, with 3′-trailer)with 1 mM CoCl2 | 0.145 | 2.6 × 10⁻⁴ | 557.7 | pH 7.5, 37 °C | PMID 32982996 | Open record: mpy-RNase Z, precursor tRNA-Arg1 of Methanolobus psychrophilus R15 (CCA-less, with 3′-trailer) |
| mpy-RNase Z | Methanolobus psychrophilus | precursor tRNA-Arg2 of Methanolobus psychrophilus R15 (genetically encoded CCA, with 3′-trailer) | 0.2 | 4.3 × 10⁻⁴ | 465.2 | pH 7.5, 37 °C | PMID 32982996 | Open record: mpy-RNase Z, precursor tRNA-Arg2 of Methanolobus psychrophilus R15 (genetically encoded CCA, with 3′-trailer) |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 7.4 | 8.5 | 0.9 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1), bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant C25G | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 3.9 | 13.2 | 0.3 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant C25G, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant C40G | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 3.1 | 6 | 0.5 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant C40G, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant E208A | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 4 | 3.5 | 1.2 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant E208A, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant F51L | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 2.3 | 6.5 | 0.4 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant F51L, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant G62V | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 0.8 | 8 | 0.1 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant G62V, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant P178A | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 1.8 | 1.2 | 1.5 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant P178A, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant P64A | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 4.6 | 22.2 | 0.2 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant P64A, bis(p-nitrophenyl) phosphate |
| tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1)variant R252G | Arabidopsis thaliana | bis(p-nitrophenyl) phosphate | 68.5 | 1.8 | 38.2 | pH 7.4, 37 °C | PMID 18052196 | Open record: tRNase Z (AthTRZ1, Arabidopsis thaliana tRNase ZS1) variant R252G, bis(p-nitrophenyl) phosphate |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7443U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.232 | 6.33 × 10⁻⁵ | 3.7 × 10³ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7443U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7444C→U substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.153 | 6.9 × 10⁻⁶ | 2.12 × 10⁴ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7444C→U substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.0127 | 1.97 × 10⁻⁵ | 670 | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→C substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.345 | 8.55 × 10⁻⁵ | 4 × 10³ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7445U→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7510A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.048 | 1.08 × 10⁻⁵ | 5.2 × 10³ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7510A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7511A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.053 | 7.6 × 10⁻⁶ | 7.7 × 10³ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7511A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7512A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer | 0.045 | 4 × 10⁻⁶ | 1.12 × 10⁴ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)) carrying the naturally occurring 7512A→G substitution (mitochondrial genome numbering): 69-nt tRNA with mature 5' end and 19-nt 3' end trailer |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human mitochondrial pre-tRNA(Ser(UCN)), wild type: 69-nt tRNA with mature 5' end and 19-nt 3' end trailer (88 nt) | 0.073 | 4.8 × 10⁻⁶ | 1.68 × 10⁴ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human mitochondrial pre-tRNA(Ser(UCN)), wild type: 69-nt tRNA with mature 5' end and 19-nt 3' end trailer (88 nt) |
| tRNase Z^L (long form, ELAC2) | Homo sapiens | human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt) | 6.18 | 2.2 × 10⁻⁵ | 2.67 × 10⁵ | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^L (long form, ELAC2), human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt) |
| tRNase Z^S (short form, ELAC1) | Homo sapiens | human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt) | 0.0207 | 1.32 × 10⁻⁴ | 162 | pH 6.75, 37 °C | PMID 16361254 | Open record: tRNase Z^S (short form, ELAC1), human nuclear-encoded pre-tRNA(Arg): 73-nt tRNA with mature 5' end and 18-nt 3' end trailer (91 nt) |