Values CatLog read from this paper
Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins
PMID 2015912doi:10.1016/0014-5793(91)80362-7Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 25 records (48 values) from this paper: HIV-1 proteinase (PR), HIV-2 proteinase (PR) from human immunodeficiency virus type 1, human immunodeficiency virus type 2.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide i (MA/CA cleavage site of HIV-1 Gag) | — | — | 45.3 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide i (MA/CA cleavage site of HIV-1 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide ii (CA/X cleavage site of HIV-1 Gag) | — | — | 90 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide ii (CA/X cleavage site of HIV-1 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide iv (X/NC cleavage site of HIV-1 Gag) | 3.7 | — | 74 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide iv (X/NC cleavage site of HIV-1 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide ix (TF/PR cleavage site of HIV-1 Gag-Pol) | 0.06 | — | 6.9 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide ix (TF/PR cleavage site of HIV-1 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide vi (NC/p6 cleavage site of HIV-1 Gag) | 0.3 | 0.53 | 0.6 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide vi (NC/p6 cleavage site of HIV-1 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide viii (internal p6 cleavage site of HIV-1 Gag) | 0.01 | 0.47 | 0.02 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide viii (internal p6 cleavage site of HIV-1 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide x (PR/RT cleavage site of HIV-1 Gag-Pol) | 1.5 | — | 24.1 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide x (PR/RT cleavage site of HIV-1 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xi (internal RT cleavage site of HIV-1 Gag-Pol) | 0.4 | 0.04 | 10 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xi (internal RT cleavage site of HIV-1 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xii (RT/IN cleavage site of HIV-1 Gag-Pol) | 1.2 | 0.006 | 202 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xii (RT/IN cleavage site of HIV-1 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xiii (MA/CA cleavage site of HIV-2 Gag) | 2.4 | — | — | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xiii (MA/CA cleavage site of HIV-2 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xiv (CA/X cleavage site of HIV-2 Gag) | — | 0.13 | — | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xiv (CA/X cleavage site of HIV-2 Gag) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xix (PR/RT cleavage site of HIV-2 Gag-Pol) | — | 0.02 | 110 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xix (PR/RT cleavage site of HIV-2 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xviii (TF/PR cleavage site of HIV-2 Gag-Pol) | 1.9 | — | 14.6 | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xviii (TF/PR cleavage site of HIV-2 Gag-Pol) |
| HIV-1 proteinase (PR) | human immunodeficiency virus type 1 | oligopeptide xxi (RT/IN cleavage site of HIV-2 Gag-Pol) | 0.3 | — | — | pH 5.6, 37 °C | Open record: HIV-1 proteinase (PR), oligopeptide xxi (RT/IN cleavage site of HIV-2 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide ii (CA/X cleavage site of HIV-1 Gag) | — | 0.03 | — | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide ii (CA/X cleavage site of HIV-1 Gag) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide iv (X/NC cleavage site of HIV-1 Gag) | — | 0.08 | — | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide iv (X/NC cleavage site of HIV-1 Gag) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide ix (TF/PR cleavage site of HIV-1 Gag-Pol) | 0.06 | — | 6.2 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide ix (TF/PR cleavage site of HIV-1 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide vi (NC/p6 cleavage site of HIV-1 Gag) | 0.2 | 0.3 | 0.7 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide vi (NC/p6 cleavage site of HIV-1 Gag) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide viii (internal p6 cleavage site of HIV-1 Gag) | 0.09 | 0.42 | 0.21 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide viii (internal p6 cleavage site of HIV-1 Gag) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide x (PR/RT cleavage site of HIV-1 Gag-Pol) | 0.4 | 0.06 | 6.7 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide x (PR/RT cleavage site of HIV-1 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide xi (internal RT cleavage site of HIV-1 Gag-Pol) | 1 | — | 5.8 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide xi (internal RT cleavage site of HIV-1 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide xii (RT/IN cleavage site of HIV-1 Gag-Pol) | 1.2 | 0.005 | 240 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide xii (RT/IN cleavage site of HIV-1 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide xiv (CA/X cleavage site of HIV-2 Gag) | — | 0.08 | — | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide xiv (CA/X cleavage site of HIV-2 Gag) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide xix (PR/RT cleavage site of HIV-2 Gag-Pol) | — | 0.02 | — | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide xix (PR/RT cleavage site of HIV-2 Gag-Pol) |
| HIV-2 proteinase (PR) | human immunodeficiency virus type 2 | oligopeptide xvii (NC/p6 cleavage site of HIV-2 Gag) | — | — | 1 | pH 5.6, 37 °C | Open record: HIV-2 proteinase (PR), oligopeptide xvii (NC/p6 cleavage site of HIV-2 Gag) |