Values CatLog read from this paper
Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid
PMID 14709911doi:10.1248/bpb.27.113Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 20 records (60 values) from this paper: pyroglutamyl aminopeptidase I (PAP-I) from Rattus norvegicus, Homo sapiens, Mus musculus.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| pyroglutamyl aminopeptidase I (PAP-I) | Homo sapiens | 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide | 1.8 | 0.5 | 3.7 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide |
| pyroglutamyl aminopeptidase I (PAP-I) | Homo sapiens | L-2-oxoimidazolidine-4-carbonyl-L-alanine | 2.4 | 0.33 | 7.2 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxoimidazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Homo sapiens | L-2-oxooxazolidine-4-carbonyl-L-alanine | 6.4 | 0.55 | 11.5 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxooxazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Homo sapiens | L-2-oxothiazolidine-4-carbonyl-L-alanine | 2.3 | 0.3 | 7.6 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Homo sapiens | L-pyroglutamyl-L-alanine | 2.4 | 0.045 | 53.3 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-pyroglutamyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Mus musculus | 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide | 2.3 | 0.58 | 3.9 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide |
| pyroglutamyl aminopeptidase I (PAP-I) | Mus musculus | L-2-oxoimidazolidine-4-carbonyl-L-alanine | 2.7 | 0.37 | 7.2 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxoimidazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Mus musculus | L-2-oxooxazolidine-4-carbonyl-L-alanine | 6.6 | 0.57 | 11.7 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxooxazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Mus musculus | L-2-oxothiazolidine-4-carbonyl-L-alanine | 2.5 | 0.33 | 7.5 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Mus musculus | L-pyroglutamyl-L-alanine | 3.2 | 0.046 | 70.3 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-pyroglutamyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide | 2.3 | 0.55 | 4.2 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), 4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxoimidazolidine-4-carbonyl-L-alanine | 3.6 | 0.42 | 8.4 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxoimidazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxooxazolidine-4-carbonyl-aminoethylnitrate | 7.6 | 1.53 | 5 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxooxazolidine-4-carbonyl-aminoethylnitrate |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxooxazolidine-4-carbonyl-L-alanine | 8.1 | 0.71 | 11.3 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxooxazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxothiazolidine-4-carbonyl-D-2-aminopropylnitrate | 1.5 | 1.43 | 1 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-D-2-aminopropylnitrate |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxothiazolidine-4-carbonyl-ethanolamine | 0.9 | 0.62 | 1.5 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-ethanolamine |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxothiazolidine-4-carbonyl-L-2-aminopropylnitrate | 3.2 | 0.57 | 5.5 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-L-2-aminopropylnitrate |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-2-oxothiazolidine-4-carbonyl-L-alanine | 3.4 | 0.43 | 7.8 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-2-oxothiazolidine-4-carbonyl-L-alanine |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-pyroglutamyl-aminoethylnitrate | 3.5 | 0.14 | 24.1 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-pyroglutamyl-aminoethylnitrate |
| pyroglutamyl aminopeptidase I (PAP-I) | Rattus norvegicus | L-pyroglutamyl-L-alanine | 3.7 | 0.057 | 64.2 | pH 7.4, 37 °C | Open record: pyroglutamyl aminopeptidase I (PAP-I), L-pyroglutamyl-L-alanine |