CatLogenzyme kinetics catalog

Values CatLog read from this paper

Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis

PMID 20511247doi:10.1093/glycob/cwq077Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 7 records (14 values) from this paper: neuraminidase 3 (NEU3) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 7 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 3.2.1.18

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
neuraminidase 3 (NEU3)Homo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.00640.0450.14 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant A160GHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.00750.0210.36 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant E51SHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.01420.0380.37 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant H277FHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.00750.0180.42 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant M87GHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.00220.140.016 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant R48NHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.00890.0330.27 calc.pH 5, 37 °COpen
neuraminidase 3 (NEU3)variant R48SHomo sapiens2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid0.01220.0320.38 calc.pH 5, 37 °COpen