Values CatLog read from this paper
Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid
PMID 21434666doi:10.1021/bi1020056Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 13 records (23 values) from this paper: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-2-hydroxyglutarate dehydrogenase (HgdH), glutaconate CoA-transferase (GctAB) from Clostridium symbiosum, Acidaminococcus fermentans.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| (R)-2-hydroxyglutarate dehydrogenase (HgdH) | Acidaminococcus fermentans | 2-oxo-4-hexenedioic acid | — | 1.1 | 220 | pH 8 | Open record: (R)-2-hydroxyglutarate dehydrogenase (HgdH), 2-oxo-4-hexenedioic acid |
| (R)-2-hydroxyglutarate dehydrogenase (HgdH) | Acidaminococcus fermentans | 2-oxohexanedioic acid | — | 0.88 | 550 | pH 8 | Open record: (R)-2-hydroxyglutarate dehydrogenase (HgdH), 2-oxohexanedioic acid |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (E)-glutaconyl-CoA | — | 0.25 | 27 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (E)-glutaconyl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (E,E)-2,4-hexadienedioyl-CoA | — | 0.57 | 8.2 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (E,E)-2,4-hexadienedioyl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (R)-2-hydroxyglutaryl-CoAkcat/Km calculated from Vmax | — | 0.052 | 1.6 × 10³ | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-2-hydroxyglutaryl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (R)-2-hydroxyglutaryl-CoA | 82 | — | — | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-2-hydroxyglutaryl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (R)-2-hydroxyglutaryl-pantetheine | — | 0.09 | 800 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-2-hydroxyglutaryl-pantetheine |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (R)-2-hydroxyhexanedioyl-CoA | — | 0.1 | 440 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-2-hydroxyhexanedioyl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | (R)-S-2-hydroxyglutaryl-N-acetylcysteamine | — | 0.115 | 560 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), (R)-S-2-hydroxyglutaryl-N-acetylcysteamine |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | butynedioyl-CoA | — | 2.1 | 1.4 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), butynedioyl-CoA |
| 2-hydroxyglutaryl-CoA dehydratase (HgdAB) | Clostridium symbiosum | oxalocrotonyl-CoA | — | 1.1 | 0.8 | pH 8, 25 °C | Open record: 2-hydroxyglutaryl-CoA dehydratase (HgdAB), oxalocrotonyl-CoA |
| glutaconate CoA-transferase (GctAB) | Acidaminococcus fermentans | 2-oxoglutarate | — | 1.02 | — | pH 7 | Open record: glutaconate CoA-transferase (GctAB), 2-oxoglutarate |
| glutaconate CoA-transferase (GctAB) | Acidaminococcus fermentans | oxaloacetate | — | 1.23 | — | pH 7 | Open record: glutaconate CoA-transferase (GctAB), oxaloacetate |