CatLogenzyme kinetics catalog

EC 4.2.1.167: (R)-2-hydroxyglutaryl-CoA dehydratase

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CatLog read 9 records for EC 4.2.1.167 from 1 paper, for 1 organism. Names in these papers: 2-hydroxyglutaryl-CoA dehydratase (HgdAB).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

PaperOrganismsRecords
Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acidClostridium symbiosum9

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(E)-glutaconyl-CoA—0.2527pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(E,E)-2,4-hexadienedioyl-CoA—0.578.2pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(R)-2-hydroxyglutaryl-CoAkcat/Km calculated from Vmax—0.0521.6 × 10³pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(R)-2-hydroxyglutaryl-CoA82——pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(R)-2-hydroxyglutaryl-pantetheine—0.09800pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(R)-2-hydroxyhexanedioyl-CoA—0.1440pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosum(R)-S-2-hydroxyglutaryl-N-acetylcysteamine—0.115560pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosumbutynedioyl-CoA—2.11.4pH 8, 25 °CPMID 21434666Open
2-hydroxyglutaryl-CoA dehydratase (HgdAB)Clostridium symbiosumoxalocrotonyl-CoA—1.10.8pH 8, 25 °CPMID 21434666Open