Values CatLog read from this paper
Emergence of Ceftazidime-Avibactam-Induced KPC Variants (KPC-25/127) in Intracranial Infection and Implications for Clinical Management
PMID 42385193doi:10.1002/mbo3.70363Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 9 records (27 values) from this paper: KPC-127, KPC-2, KPC-25 from Klebsiella pneumoniae.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| KPC-127 | Klebsiella pneumoniae | ceftazidime | 1.32 | 0.1056 | 13 | pH 7 | Open record: KPC-127, ceftazidime |
| KPC-127 | Klebsiella pneumoniae | imipenem | 7.41 | 0.6538 | 11 | pH 7 | Open record: KPC-127, imipenem |
| KPC-127 | Klebsiella pneumoniae | meropenem | 30.13 | 0.2226 | 140 | pH 7 | Open record: KPC-127, meropenem |
| KPC-2 | Klebsiella pneumoniae | ceftazidime | 3.51 | 0.09745 | 36 | pH 7 | Open record: KPC-2, ceftazidime |
| KPC-2 | Klebsiella pneumoniae | imipenem | 163 | 0.3126 | 520 | pH 7 | Open record: KPC-2, imipenem |
| KPC-2 | Klebsiella pneumoniae | meropenem | 100.2 | 0.1061 | 940 | pH 7 | Open record: KPC-2, meropenem |
| KPC-25 | Klebsiella pneumoniae | ceftazidime | 1.12 | 0.1067 | 10.4 | pH 7 | Open record: KPC-25, ceftazidime |
| KPC-25 | Klebsiella pneumoniae | imipenem | 4.86 | 0.7205 | 6.7 | pH 7 | Open record: KPC-25, imipenem |
| KPC-25 | Klebsiella pneumoniae | meropenem | 6.32 | 0.06453 | 98 | pH 7 | Open record: KPC-25, meropenem |