Values CatLog read from this paper
Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes
PMID 18779312doi:10.1124/dmd.108.023770Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 10 records (30 values) from this paper: CYP2A13, CYP2A6, CYP1A2 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| CYP1A2 | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.1613 | 0.0273 | 6 | pH 7.4, 37 °C | Open record: CYP1A2, N-(4-ethoxyphenyl)acetamide |
| CYP2A13 | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0637 | 0.0107 | 6 | pH 7.4, 37 °C | Open record: CYP2A13, N-(4-ethoxyphenyl)acetamide |
| CYP2A13variant A117V | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.49 | 0.0478 | 10.3 | pH 7.4, 37 °C | Open record: CYP2A13 variant A117V, N-(4-ethoxyphenyl)acetamide |
| CYP2A13variant A213S | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0357 | 0.0206 | 1.7 | pH 7.4, 37 °C | Open record: CYP2A13 variant A213S, N-(4-ethoxyphenyl)acetamide |
| CYP2A13variant H372R | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0318 | 0.0048 | 6.7 | pH 7.4, 37 °C | Open record: CYP2A13 variant H372R, N-(4-ethoxyphenyl)acetamide |
| CYP2A13variant L366I | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.228 | 0.0363 | 6.3 | pH 7.4, 37 °C | Open record: CYP2A13 variant L366I, N-(4-ethoxyphenyl)acetamide |
| CYP2A13variant M365V | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0155 | 0.0204 | 0.83 | pH 7.4, 37 °C | Open record: CYP2A13 variant M365V, N-(4-ethoxyphenyl)acetamide |
| CYP2A6variant I208S/I300F/G301A | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0163 | 0.0389 | 0.5 | pH 7.4, 37 °C | Open record: CYP2A6 variant I208S/I300F/G301A, N-(4-ethoxyphenyl)acetamide |
| CYP2A6variant I208S/I300F/G301A/S369G | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.048 | 0.0103 | 4.7 | pH 7.4, 37 °C | Open record: CYP2A6 variant I208S/I300F/G301A/S369G, N-(4-ethoxyphenyl)acetamide |
| CYP2A6variant I300F/G301A/S369G | Homo sapiens | N-(4-ethoxyphenyl)acetamide | 0.0148 | 0.0049 | 3 | pH 7.4, 37 °C | Open record: CYP2A6 variant I300F/G301A/S369G, N-(4-ethoxyphenyl)acetamide |