Values CatLog read from this paper
Molecular Interplay between the Dimer Interface and the Substrate-Binding Site of Human Peptidylarginine Deiminase 4
PMID 28209966doi:10.1038/srep42662Open in Browse
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CatLog read 30 records (90 values) from this paper: peptidylarginine deiminase 4 (PAD4) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| peptidylarginine deiminase 4 (PAD4) | Homo sapiens | benzoyl-L-arginine ethyl ester | 11.7 | 0.5 | 23.4 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4), benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant C434A | Homo sapiens | benzoyl-L-arginine ethyl ester | 8 | 0.4 | 20 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant C434A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant D465A | Homo sapiens | benzoyl-L-arginine ethyl ester | 3.5 | 0.4 | 8.8 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant D465A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant F285A | Homo sapiens | benzoyl-L-arginine ethyl ester | 6.9 | 0.8 | 8.6 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant F285A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant F541A | Homo sapiens | benzoyl-L-arginine ethyl ester | 7.7 | 0.7 | 11 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant F541A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant F576A | Homo sapiens | benzoyl-L-arginine ethyl ester | 9.8 | 0.4 | 24.5 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant F576A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L279A | Homo sapiens | benzoyl-L-arginine ethyl ester | 5.5 | 0.4 | 13.8 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L279A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L279D | Homo sapiens | benzoyl-L-arginine ethyl ester | 3.6 | 1.9 | 1.9 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L279D, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L279I | Homo sapiens | benzoyl-L-arginine ethyl ester | 11.2 | 0.4 | 28 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L279I, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L6A | Homo sapiens | benzoyl-L-arginine ethyl ester | 7.3 | 0.6 | 12.2 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L6A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L6D | Homo sapiens | benzoyl-L-arginine ethyl ester | 4.5 | 0.5 | 9 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L6D, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant L6I | Homo sapiens | benzoyl-L-arginine ethyl ester | 10.9 | 0.5 | 21.8 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant L6I, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R372A | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.07 | 3.7 | 0.02 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R372A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R372Q | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.12 | 2.3 | 0.05 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R372Q, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R374A | Homo sapiens | benzoyl-L-arginine ethyl ester | 7.8 | 0.7 | 11.1 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R374A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R374Q | Homo sapiens | benzoyl-L-arginine ethyl ester | 3.7 | 0.4 | 9.3 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R374Q, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R441A | Homo sapiens | benzoyl-L-arginine ethyl ester | 2.3 | 1.7 | 1.4 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R441A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant R639A | Homo sapiens | benzoyl-L-arginine ethyl ester | 5 | 0.7 | 7.1 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant R639A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V283A | Homo sapiens | benzoyl-L-arginine ethyl ester | 8 | 0.7 | 11.4 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V283A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V283I | Homo sapiens | benzoyl-L-arginine ethyl ester | 9.5 | 0.5 | 19 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V283I, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V283T | Homo sapiens | benzoyl-L-arginine ethyl ester | 5.5 | 0.9 | 6.3 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V283T, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V284A | Homo sapiens | benzoyl-L-arginine ethyl ester | 5.5 | 1.5 | 3.7 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V284A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V284D | Homo sapiens | benzoyl-L-arginine ethyl ester | 2.9 | 0.9 | 3.2 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V284D, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V284I | Homo sapiens | benzoyl-L-arginine ethyl ester | 10.9 | 0.5 | 21.8 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V284I, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V469A | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.8 | 5.3 | 0.15 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V469A, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V469L | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.1 | 1 | 0.1 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V469L, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant V469T | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.04 | 0.1 | 0.4 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant V469T, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant W548F | Homo sapiens | benzoyl-L-arginine ethyl ester | 6.2 | 1.4 | 4.6 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant W548F, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant W548K | Homo sapiens | benzoyl-L-arginine ethyl ester | 0.6 | 0.3 | 2 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant W548K, benzoyl-L-arginine ethyl ester |
| peptidylarginine deiminase 4 (PAD4)variant Y435A | Homo sapiens | benzoyl-L-arginine ethyl ester | 2.8 | 3.2 | 0.9 | pH 7.5, 25 °C | Open record: peptidylarginine deiminase 4 (PAD4) variant Y435A, benzoyl-L-arginine ethyl ester |