Values CatLog read from this paper
Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase
PMID 27136302doi:10.1021/acs.biochem.5b01301Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (35 values) from this paper: FabV enoyl-ACP reductase from Yersinia pestis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 1 kcat/Km value marked “calc.” from kcat and Km; no printed kcat/Km was read for that record.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| FabV enoyl-ACP reductase | Yersinia pestis | NADH | — | 0.01 | — | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, NADH |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-decenoyl-CoA | 5.53 | 0.023 | 230 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-decenoyl-CoA |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-dodecenoyl-CoA | 91.13 | 0.014 | 6.5 × 10³ | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-dodecenoyl-CoA5 nM enzyme | 97.67 | 0.019 | 5.1 × 10³ calc. | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-dodecenoyl-E. coli acyl-carrier-protein | — | — | 1.365 × 10⁴ | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-E. coli acyl-carrier-protein |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-octenoyl-CoA | 0.27 | 0.007 | 33 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-octenoyl-CoA |
| FabV enoyl-ACP reductase | Yersinia pestis | trans-2-octenoyl-E. coli acyl-carrier-protein | 14.92 | 0.006 | 2.5 × 10³ | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase, trans-2-octenoyl-E. coli acyl-carrier-protein |
| FabV enoyl-ACP reductasevariant P142W | Yersinia pestis | trans-2-dodecenoyl-CoA | 64.43 | 0.012 | 5.82 × 10³ | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant P142W, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductasevariant T276A | Yersinia pestis | trans-2-dodecenoyl-CoA | 2.22 | 0.053 | 17 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276A, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductasevariant T276C | Yersinia pestis | trans-2-dodecenoyl-E. coli acyl-carrier-protein | — | — | 0.17 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276C, trans-2-dodecenoyl-E. coli acyl-carrier-protein |
| FabV enoyl-ACP reductasevariant T276G | Yersinia pestis | trans-2-dodecenoyl-CoA | 5.98 | 0.038 | 170 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276G, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductasevariant T276S | Yersinia pestis | trans-2-dodecenoyl-CoA | 83.9 | 0.018 | 4.7 × 10³ | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276S, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductasevariant T276V | Yersinia pestis | trans-2-dodecenoyl-CoA | 0.25 | 0.017 | 17 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276V, trans-2-dodecenoyl-CoA |
| FabV enoyl-ACP reductasevariant T276Y | Yersinia pestis | trans-2-dodecenoyl-CoA | 0.083 | 0.015 | 5 | pH 8, 25 °C | Open record: FabV enoyl-ACP reductase variant T276Y, trans-2-dodecenoyl-CoA |