EC 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH)

OxidoreductasesOpen in Browse

CatLog read 114 records for EC 1.3.1.9 from 11 papers, for 8 organisms. Names in these papers: FabV enoyl-ACP reductase, enoyl-ACP reductase (PfENR), InhA, enoyl reductase FabI and 6 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 131 records for EC 1.3.1.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.3.1.9 in Browse.

Papers

Papers with records for EC 1.3.1.9
Paper	Organisms	Records
Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei	Burkholderia mallei	19
Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum	Plasmodium falciparum	17
Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase	Yersinia pestis	14
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis	Mycobacterium tuberculosis	14
Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs	Escherichia coli	12
Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid	Mycobacterium tuberculosis	10
Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability	Mycobacterium tuberculosis	10
Purification and characterizations of beta-Ketoacyl-[acyl-carrier-protein] reductase, beta-hydroxyacyl-[acyl-carrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia…	Spinacia oleracea	8
Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei	Burkholderia pseudomallei	5
Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis	Mycobacterium tuberculosis	4
The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis	Bacillus subtilis	1

Records

Records for EC 1.3.1.9 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
bpmFabI-1 (FabI enoyl-ACP reductase)	Burkholderia pseudomallei	Crotonyl-ACP	4.03	0.027	150	pH 6.8, 25 °C	PMID 21393229	Open record: bpmFabI-1 (FabI enoyl-ACP reductase), Crotonyl-ACP
bpmFabI-1 (FabI enoyl-ACP reductase)	Burkholderia pseudomallei	trans-2-butenoyl-CoA	3.58	0.188	20	pH 6.8, 25 °C	PMID 21393229	Open record: bpmFabI-1 (FabI enoyl-ACP reductase), trans-2-butenoyl-CoA
bpmFabI-1 (FabI enoyl-ACP reductase)	Burkholderia pseudomallei	trans-2-decenoyl-CoA	5.58	0.0056	1 × 10³	pH 6.8, 25 °C	PMID 21393229	Open record: bpmFabI-1 (FabI enoyl-ACP reductase), trans-2-decenoyl-CoA
bpmFabI-1 (FabI enoyl-ACP reductase)	Burkholderia pseudomallei	trans-2-dodecenoyl-CoA	8.4	0.0017	5 × 10³	pH 6.8, 25 °C	PMID 21393229	Open record: bpmFabI-1 (FabI enoyl-ACP reductase), trans-2-dodecenoyl-CoA
bpmFabI-1 (FabI enoyl-ACP reductase)	Burkholderia pseudomallei	trans-2-octenoyl-CoA	28.3	0.16	180	pH 6.8, 25 °C	PMID 21393229	Open record: bpmFabI-1 (FabI enoyl-ACP reductase), trans-2-octenoyl-CoA
enoyl reductase FabI	Escherichia coli	NADH	—	0.02	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI, NADH
enoyl reductase FabI	Escherichia coli	trans-2-dodecenoyl-CoA	11.87	0.03	400	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI, trans-2-dodecenoyl-CoA
enoyl reductase FabIvariant A197M	Escherichia coli	NADH	—	0.345	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant A197M, NADH
enoyl reductase FabIvariant A197M	Escherichia coli	trans-2-dodecenoyl-CoA	8.15	0.009	880	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant A197M, trans-2-dodecenoyl-CoA
enoyl reductase FabIvariant F203L	Escherichia coli	NADH	—	0.037	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant F203L, NADH
enoyl reductase FabIvariant F203L	Escherichia coli	trans-2-dodecenoyl-CoA	10.57	0.035	302	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant F203L, trans-2-dodecenoyl-CoA
enoyl reductase FabIvariant G93V	Escherichia coli	NADH	—	0.01	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant G93V, NADH
enoyl reductase FabIvariant G93V	Escherichia coli	trans-2-dodecenoyl-CoA	5	0.003	1.67 × 10³	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant G93V, trans-2-dodecenoyl-CoA
enoyl reductase FabIvariant M159T	Escherichia coli	NADH	—	0.4	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant M159T, NADH
enoyl reductase FabIvariant M159T	Escherichia coli	trans-2-dodecenoyl-CoA	0.45	0.079	5.5	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant M159T, trans-2-dodecenoyl-CoA
enoyl reductase FabIvariant Y156F	Escherichia coli	NADH	—	0.051	—	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant Y156F, NADH
enoyl reductase FabIvariant Y156F	Escherichia coli	trans-2-dodecenoyl-CoA	1.75	0.029	60	pH 8, 25 °C	PMID 12693936	Open record: enoyl reductase FabI variant Y156F, trans-2-dodecenoyl-CoA
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	NADH	—	0.011	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, NADH
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-butenoyl-[acyl-carrier protein] (crotonyl-ACP)	—	0.0015	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-butenoyl-[acyl-carrier protein] (crotonyl-ACP)
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-butenoyl-CoA (crotonyl-CoA)	—	0.04	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-butenoyl-CoA (crotonyl-CoA)
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-decenoyl-[acyl-carrier protein]	—	0.0011	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-decenoyl-[acyl-carrier protein]
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-dodecenoyl-[acyl-carrier protein]	—	0.005	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-dodecenoyl-[acyl-carrier protein]
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-hexadecenoyl-[acyl-carrier protein]	—	0.0071	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-hexadecenoyl-[acyl-carrier protein]
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-hexenoyl-[acyl-carrier protein]	—	0.0013	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-hexenoyl-[acyl-carrier protein]
enoyl-[acyl-carrier-protein] reductase	Spinacia oleracea	trans-2-octenoyl-[acyl-carrier protein]	—	0.0018	—	pH 6.4, 25 °C	PMID 6756317	Open record: enoyl-[acyl-carrier-protein] reductase, trans-2-octenoyl-[acyl-carrier protein]
enoyl-[acyl-carrier-protein] reductase FabI (bsFabI)	Bacillus subtilis	NADH	—	0.007	—	25 °C	PMID 11007778	Open record: enoyl-[acyl-carrier-protein] reductase FabI (bsFabI), NADH
enoyl-ACP reductase (PfENR)	Plasmodium falciparum	crotonoyl-CoA	1.62	0.16	10 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR), crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant A217G	Plasmodium falciparum	crotonoyl-CoA	0.9	0.173	5.2 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant A217G, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant A217G	Plasmodium falciparum	NADH	—	0.035	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant A217G, NADH
enoyl-ACP reductase (PfENR)variant A217V	Plasmodium falciparum	crotonoyl-CoA	1.2	0.15	8.0 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant A217V, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant A217V	Plasmodium falciparum	NADH	—	0.028	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant A217V, NADH
enoyl-ACP reductase (PfENR)variant F368A	Plasmodium falciparum	crotonoyl-CoA	—	0.152	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant F368A, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant F368A	Plasmodium falciparum	NADH	—	0.031	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant F368A, NADH
enoyl-ACP reductase (PfENR)variant F368I	Plasmodium falciparum	crotonoyl-CoA	1.05	0.147	7.14 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant F368I, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant F368I	Plasmodium falciparum	NADH	—	0.035	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant F368I, NADH
enoyl-ACP reductase (PfENR)variant M281A	Plasmodium falciparum	crotonoyl-CoA	—	0.168	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant M281A, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant M281A	Plasmodium falciparum	NADH	—	0.039	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant M281A, NADH
enoyl-ACP reductase (PfENR)variant M281T	Plasmodium falciparum	crotonoyl-CoA	1.1	0.155	7.1 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant M281T, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant M281T	Plasmodium falciparum	NADH	—	0.025	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant M281T, NADH
enoyl-ACP reductase (PfENR)variant N218A	Plasmodium falciparum	crotonoyl-CoA	—	0.152	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant N218A, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant N218A	Plasmodium falciparum	NADH	—	0.073	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant N218A, NADH
enoyl-ACP reductase (PfENR)variant N218D	Plasmodium falciparum	crotonoyl-CoA	1.5	0.165	9.1 calc.	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant N218D, crotonoyl-CoA
enoyl-ACP reductase (PfENR)variant N218D	Plasmodium falciparum	NADH	—	0.1	—	pH 7.4, 25 °C	PMID 15139852	Open record: enoyl-ACP reductase (PfENR) variant N218D, NADH
enoyl-ACP reductase InhA	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	5.34	0.0409	165	pH 7.5, 25 °C	PMID 21143326	Open record: enoyl-ACP reductase InhA, trans-2-dodecenoyl-CoA
enoyl-ACP reductase InhAvariant T266A	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	7.123	0.0523	137	pH 7.5, 25 °C	PMID 21143326	Open record: enoyl-ACP reductase InhA variant T266A, trans-2-dodecenoyl-CoA
enoyl-ACP reductase InhAvariant T266D	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	1.455	0.0196	100	pH 7.5, 25 °C	PMID 21143326	Open record: enoyl-ACP reductase InhA variant T266D, trans-2-dodecenoyl-CoA
enoyl-ACP reductase InhAvariant T266E	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	2.49	0.0203	115	pH 7.5, 25 °C	PMID 21143326	Open record: enoyl-ACP reductase InhA variant T266E, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Burkholderia mallei	crotonyl-acyl carrier protein (ftuACP from Francisella tularensis SCHU S4 acylated with crotonic anhydride)	21.65	0.0251	863 calc.	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, crotonyl-acyl carrier protein (ftuACP from Francisella tularensis SCHU S4 acylated with crotonic anhydride)
FabV enoyl-ACP reductase	Burkholderia mallei	reduced nicotinamide adenine dinucleotideNADH oxidation followed at 340 nm; cosubstrate DD-CoA	—	0.023	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductase	Burkholderia mallei	reduced nicotinamide adenine dinucleotideNADH oxidation followed at 340 nm; cosubstrate DD-CoA	—	0.0287	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductase	Burkholderia mallei	reduced nicotinamide adenine dinucleotidecosubstrate crotonyl-ACP (Cr-ACP); in the text	—	0.031	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductase	Burkholderia mallei	trans-2-dodecenoyl-CoAN-terminal His tag removed with thrombin; Table 2	28.8	0.0044	6.53 × 10³	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Burkholderia mallei	trans-2-dodecenoyl-CoAN-terminal His tag; Table 2	20.7	0.0025	8.28 × 10³	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Burkholderia mallei	trans-2-dodecenoyl-CoAN-terminal His tag; in the text	15.5	0.0024	6.5 × 10³ calc.	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant K244A	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.066	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244A, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant K244A	Burkholderia mallei	trans-2-dodecenoyl-CoA	0.18	0.0072	25	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244A, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant K244A/K245A	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.065	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244A/K245A, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant K244A/K245A	Burkholderia mallei	trans-2-dodecenoyl-CoA	—	—	0.38	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244A/K245A, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant K244R	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.069	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244R, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant K244R	Burkholderia mallei	trans-2-dodecenoyl-CoA	0.022	0.0076	2.8	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K244R, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant K245M	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.028	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K245M, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant K245M	Burkholderia mallei	trans-2-dodecenoyl-CoA	0.3	0.028	10.7	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant K245M, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant Y235A	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.023	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant Y235A, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant Y235A	Burkholderia mallei	trans-2-dodecenoyl-CoA	0.083	0.0027	30	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant Y235A, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant Y235S	Burkholderia mallei	reduced nicotinamide adenine dinucleotide	—	0.006	—	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant Y235S, reduced nicotinamide adenine dinucleotide
FabV enoyl-ACP reductasevariant Y235S	Burkholderia mallei	trans-2-dodecenoyl-CoA	0.102	0.0022	47	pH 7.9, 25 °C	PMID 20055482	Open record: FabV enoyl-ACP reductase variant Y235S, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Yersinia pestis	NADH	—	0.01	—	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, NADH
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-decenoyl-CoA	5.53	0.023	230	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-decenoyl-CoA
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-dodecenoyl-CoA	91.13	0.014	6.5 × 10³	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-dodecenoyl-CoA5 nM enzyme	97.67	0.019	5.1 × 10³ calc.	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-dodecenoyl-E. coli acyl-carrier-protein	—	—	1.365 × 10⁴	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-dodecenoyl-E. coli acyl-carrier-protein
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-octenoyl-CoA	0.27	0.007	33	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-octenoyl-CoA
FabV enoyl-ACP reductase	Yersinia pestis	trans-2-octenoyl-E. coli acyl-carrier-protein	14.92	0.006	2.5 × 10³	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase, trans-2-octenoyl-E. coli acyl-carrier-protein
FabV enoyl-ACP reductasevariant P142W	Yersinia pestis	trans-2-dodecenoyl-CoA	64.43	0.012	5.82 × 10³	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant P142W, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant T276A	Yersinia pestis	trans-2-dodecenoyl-CoA	2.22	0.053	17	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276A, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant T276C	Yersinia pestis	trans-2-dodecenoyl-E. coli acyl-carrier-protein	—	—	0.17	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276C, trans-2-dodecenoyl-E. coli acyl-carrier-protein
FabV enoyl-ACP reductasevariant T276G	Yersinia pestis	trans-2-dodecenoyl-CoA	5.98	0.038	170	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276G, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant T276S	Yersinia pestis	trans-2-dodecenoyl-CoA	83.9	0.018	4.7 × 10³	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276S, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant T276V	Yersinia pestis	trans-2-dodecenoyl-CoA	0.25	0.017	17	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276V, trans-2-dodecenoyl-CoA
FabV enoyl-ACP reductasevariant T276Y	Yersinia pestis	trans-2-dodecenoyl-CoA	0.083	0.015	5	pH 8, 25 °C	PMID 27136302	Open record: FabV enoyl-ACP reductase variant T276Y, trans-2-dodecenoyl-CoA
InhA	Mycobacterium tuberculosis	C2-ene adduct	3	0.011	270 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA, C2-ene adduct
InhA	Mycobacterium tuberculosis	NADH	3.5	0.09	39 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA, NADH
InhA	Mycobacterium tuberculosis	Octenoyl-CoA	3.6	0.8	4.5 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA, Octenoyl-CoA
InhAvariant T196A	Mycobacterium tuberculosis	C2-ene adduct	0.077	0.01	7.7 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196A, C2-ene adduct
InhAvariant T196A	Mycobacterium tuberculosis	NADH	0.012	0.059	0.20 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196A, NADH
InhAvariant T196A	Mycobacterium tuberculosis	Octenoyl-CoA	0.05	7.6	0.0066 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196A, Octenoyl-CoA
InhAvariant T196V	Mycobacterium tuberculosis	C2-ene adduct	0.056	0.022	2.5 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196V, C2-ene adduct
InhAvariant T196V	Mycobacterium tuberculosis	NADH	0.0051	0.11	0.046 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196V, NADH
InhAvariant T196V	Mycobacterium tuberculosis	Octenoyl-CoA	0.0073	4.3	0.0017 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant T196V, Octenoyl-CoA
InhAvariant Y158F	Mycobacterium tuberculosis	NADH	0.079	0.01	7.9 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant Y158F, NADH
InhAvariant Y158F	Mycobacterium tuberculosis	Octenoyl-CoA	0.088	2	0.044 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant Y158F, Octenoyl-CoA
InhAvariant Y158S	Mycobacterium tuberculosis	C2-ene adduct	0.23	0.03	7.7 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant Y158S, C2-ene adduct
InhAvariant Y158S	Mycobacterium tuberculosis	NADH	0.0059	0.056	0.11 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant Y158S, NADH
InhAvariant Y158S	Mycobacterium tuberculosis	Octenoyl-CoA	0.0055	0.9	0.0061 calc.	pH 6.8, 30 °C	PMID 30217823	Open record: InhA variant Y158S, Octenoyl-CoA
InhA (2-trans-enoyl-AcpM reductase)	Mycobacterium tuberculosis	NADH	17.03	0.098	173	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase), NADH
InhA (2-trans-enoyl-AcpM reductase)	Mycobacterium tuberculosis	trans-2-dodecenoyl-coenzyme A	11.57	0.075	155	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase), trans-2-dodecenoyl-coenzyme A
InhA (2-trans-enoyl-AcpM reductase)variant M155A	Mycobacterium tuberculosis	NADH	17.9	0.065	277	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant M155A, NADH
InhA (2-trans-enoyl-AcpM reductase)variant M155A	Mycobacterium tuberculosis	trans-2-dodecenoyl-coenzyme A	7.43	0.026	283	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant M155A, trans-2-dodecenoyl-coenzyme A
InhA (2-trans-enoyl-AcpM reductase)variant P193A	Mycobacterium tuberculosis	NADH	0.097	0.005	20	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant P193A, NADH
InhA (2-trans-enoyl-AcpM reductase)variant P193A	Mycobacterium tuberculosis	trans-2-dodecenoyl-coenzyme A	0.42	0.053	8.3	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant P193A, trans-2-dodecenoyl-coenzyme A
InhA (2-trans-enoyl-AcpM reductase)variant S94A	Mycobacterium tuberculosis	NADH	29.1	0.211	142	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant S94A, NADH
InhA (2-trans-enoyl-AcpM reductase)variant S94A	Mycobacterium tuberculosis	trans-2-dodecenoyl-coenzyme A	13.15	0.106	123	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant S94A, trans-2-dodecenoyl-coenzyme A
InhA (2-trans-enoyl-AcpM reductase)variant W222A	Mycobacterium tuberculosis	NADH	10.27	0.083	125	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant W222A, NADH
InhA (2-trans-enoyl-AcpM reductase)variant W222A	Mycobacterium tuberculosis	trans-2-dodecenoyl-coenzyme A	17.58	0.145	122	pH 7.5, 37 °C	PMID 28680153	Open record: InhA (2-trans-enoyl-AcpM reductase) variant W222A, trans-2-dodecenoyl-coenzyme A
InhA (enoyl-ACP reductase)variant A124V	Mycobacterium tuberculosis	NADH	—	0.142	—	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant A124V, NADH
InhA (enoyl-ACP reductase)variant A124V	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	14.35	0.072	198	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant A124V, trans-2-dodecenoyl-CoA
InhA (enoyl-ACP reductase)variant I21V	Mycobacterium tuberculosis	NADH	—	0.12	—	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant I21V, NADH
InhA (enoyl-ACP reductase)variant I21V	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	15.42	0.07	220	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant I21V, trans-2-dodecenoyl-CoA
InhA (enoyl-ACP reductase)variant I47T	Mycobacterium tuberculosis	NADH	—	0.152	—	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant I47T, NADH
InhA (enoyl-ACP reductase)variant I47T	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	12	0.036	333	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant I47T, trans-2-dodecenoyl-CoA
InhA (enoyl-ACP reductase)variant M161V	Mycobacterium tuberculosis	NADH	—	0.332	—	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant M161V, NADH
InhA (enoyl-ACP reductase)variant M161V	Mycobacterium tuberculosis	trans-2-hexadecenoyl-CoA	11.7	0.01	1.17 × 10³	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant M161V, trans-2-hexadecenoyl-CoA
InhA (enoyl-ACP reductase)variant S94A	Mycobacterium tuberculosis	NADH	—	0.25	—	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant S94A, NADH
InhA (enoyl-ACP reductase)variant S94A	Mycobacterium tuberculosis	trans-2-dodecenoyl-CoA	16.55	0.104	148	pH 6.8, 25 °C	PMID 10869170	Open record: InhA (enoyl-ACP reductase) variant S94A, trans-2-dodecenoyl-CoA