Values CatLog read from this paper
Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid
PMID 10869170doi:10.1021/bi0008940Open in Browse
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CatLog read 10 records (20 values) from this paper: InhA (enoyl-ACP reductase) from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| InhA (enoyl-ACP reductase)variant A124V | Mycobacterium tuberculosis | NADH | — | 0.142 | — | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant A124V, NADH |
| InhA (enoyl-ACP reductase)variant A124V | Mycobacterium tuberculosis | trans-2-dodecenoyl-CoA | 14.35 | 0.072 | 198 | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant A124V, trans-2-dodecenoyl-CoA |
| InhA (enoyl-ACP reductase)variant I21V | Mycobacterium tuberculosis | NADH | — | 0.12 | — | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant I21V, NADH |
| InhA (enoyl-ACP reductase)variant I21V | Mycobacterium tuberculosis | trans-2-dodecenoyl-CoA | 15.42 | 0.07 | 220 | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant I21V, trans-2-dodecenoyl-CoA |
| InhA (enoyl-ACP reductase)variant I47T | Mycobacterium tuberculosis | NADH | — | 0.152 | — | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant I47T, NADH |
| InhA (enoyl-ACP reductase)variant I47T | Mycobacterium tuberculosis | trans-2-dodecenoyl-CoA | 12 | 0.036 | 333 | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant I47T, trans-2-dodecenoyl-CoA |
| InhA (enoyl-ACP reductase)variant M161V | Mycobacterium tuberculosis | NADH | — | 0.332 | — | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant M161V, NADH |
| InhA (enoyl-ACP reductase)variant M161V | Mycobacterium tuberculosis | trans-2-hexadecenoyl-CoA | 11.7 | 0.01 | 1.17 × 10³ | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant M161V, trans-2-hexadecenoyl-CoA |
| InhA (enoyl-ACP reductase)variant S94A | Mycobacterium tuberculosis | NADH | — | 0.25 | — | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant S94A, NADH |
| InhA (enoyl-ACP reductase)variant S94A | Mycobacterium tuberculosis | trans-2-dodecenoyl-CoA | 16.55 | 0.104 | 148 | pH 6.8, 25 °C | Open record: InhA (enoyl-ACP reductase) variant S94A, trans-2-dodecenoyl-CoA |