Values CatLog read from this paper
Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs
PMID 12693936doi:10.1021/bi0300229Open in Browse
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CatLog read 12 records (24 values) from this paper: enoyl reductase FabI from Escherichia coli.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| enoyl reductase FabI | Escherichia coli | NADH | — | 0.02 | — | pH 8, 25 °C | Open record: enoyl reductase FabI, NADH |
| enoyl reductase FabI | Escherichia coli | trans-2-dodecenoyl-CoA | 11.87 | 0.03 | 400 | pH 8, 25 °C | Open record: enoyl reductase FabI, trans-2-dodecenoyl-CoA |
| enoyl reductase FabIvariant A197M | Escherichia coli | NADH | — | 0.345 | — | pH 8, 25 °C | Open record: enoyl reductase FabI variant A197M, NADH |
| enoyl reductase FabIvariant A197M | Escherichia coli | trans-2-dodecenoyl-CoA | 8.15 | 0.009 | 880 | pH 8, 25 °C | Open record: enoyl reductase FabI variant A197M, trans-2-dodecenoyl-CoA |
| enoyl reductase FabIvariant F203L | Escherichia coli | NADH | — | 0.037 | — | pH 8, 25 °C | Open record: enoyl reductase FabI variant F203L, NADH |
| enoyl reductase FabIvariant F203L | Escherichia coli | trans-2-dodecenoyl-CoA | 10.57 | 0.035 | 302 | pH 8, 25 °C | Open record: enoyl reductase FabI variant F203L, trans-2-dodecenoyl-CoA |
| enoyl reductase FabIvariant G93V | Escherichia coli | NADH | — | 0.01 | — | pH 8, 25 °C | Open record: enoyl reductase FabI variant G93V, NADH |
| enoyl reductase FabIvariant G93V | Escherichia coli | trans-2-dodecenoyl-CoA | 5 | 0.003 | 1.67 × 10³ | pH 8, 25 °C | Open record: enoyl reductase FabI variant G93V, trans-2-dodecenoyl-CoA |
| enoyl reductase FabIvariant M159T | Escherichia coli | NADH | — | 0.4 | — | pH 8, 25 °C | Open record: enoyl reductase FabI variant M159T, NADH |
| enoyl reductase FabIvariant M159T | Escherichia coli | trans-2-dodecenoyl-CoA | 0.45 | 0.079 | 5.5 | pH 8, 25 °C | Open record: enoyl reductase FabI variant M159T, trans-2-dodecenoyl-CoA |
| enoyl reductase FabIvariant Y156F | Escherichia coli | NADH | — | 0.051 | — | pH 8, 25 °C | Open record: enoyl reductase FabI variant Y156F, NADH |
| enoyl reductase FabIvariant Y156F | Escherichia coli | trans-2-dodecenoyl-CoA | 1.75 | 0.029 | 60 | pH 8, 25 °C | Open record: enoyl reductase FabI variant Y156F, trans-2-dodecenoyl-CoA |