Values CatLog read from this paper
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis
PMID 30217823doi:10.1074/jbc.ra118.005405Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 14 records (28 values) from this paper: InhA from Mycobacterium tuberculosis.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 14 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| InhA | Mycobacterium tuberculosis | C2-ene adduct | 3 | 0.011 | 270 calc. | pH 6.8, 30 °C | Open record: InhA, C2-ene adduct |
| InhA | Mycobacterium tuberculosis | NADH | 3.5 | 0.09 | 39 calc. | pH 6.8, 30 °C | Open record: InhA, NADH |
| InhA | Mycobacterium tuberculosis | Octenoyl-CoA | 3.6 | 0.8 | 4.5 calc. | pH 6.8, 30 °C | Open record: InhA, Octenoyl-CoA |
| InhAvariant T196A | Mycobacterium tuberculosis | C2-ene adduct | 0.077 | 0.01 | 7.7 calc. | pH 6.8, 30 °C | Open record: InhA variant T196A, C2-ene adduct |
| InhAvariant T196A | Mycobacterium tuberculosis | NADH | 0.012 | 0.059 | 0.20 calc. | pH 6.8, 30 °C | Open record: InhA variant T196A, NADH |
| InhAvariant T196A | Mycobacterium tuberculosis | Octenoyl-CoA | 0.05 | 7.6 | 0.0066 calc. | pH 6.8, 30 °C | Open record: InhA variant T196A, Octenoyl-CoA |
| InhAvariant T196V | Mycobacterium tuberculosis | C2-ene adduct | 0.056 | 0.022 | 2.5 calc. | pH 6.8, 30 °C | Open record: InhA variant T196V, C2-ene adduct |
| InhAvariant T196V | Mycobacterium tuberculosis | NADH | 0.0051 | 0.11 | 0.046 calc. | pH 6.8, 30 °C | Open record: InhA variant T196V, NADH |
| InhAvariant T196V | Mycobacterium tuberculosis | Octenoyl-CoA | 0.0073 | 4.3 | 0.0017 calc. | pH 6.8, 30 °C | Open record: InhA variant T196V, Octenoyl-CoA |
| InhAvariant Y158F | Mycobacterium tuberculosis | NADH | 0.079 | 0.01 | 7.9 calc. | pH 6.8, 30 °C | Open record: InhA variant Y158F, NADH |
| InhAvariant Y158F | Mycobacterium tuberculosis | Octenoyl-CoA | 0.088 | 2 | 0.044 calc. | pH 6.8, 30 °C | Open record: InhA variant Y158F, Octenoyl-CoA |
| InhAvariant Y158S | Mycobacterium tuberculosis | C2-ene adduct | 0.23 | 0.03 | 7.7 calc. | pH 6.8, 30 °C | Open record: InhA variant Y158S, C2-ene adduct |
| InhAvariant Y158S | Mycobacterium tuberculosis | NADH | 0.0059 | 0.056 | 0.11 calc. | pH 6.8, 30 °C | Open record: InhA variant Y158S, NADH |
| InhAvariant Y158S | Mycobacterium tuberculosis | Octenoyl-CoA | 0.0055 | 0.9 | 0.0061 calc. | pH 6.8, 30 °C | Open record: InhA variant Y158S, Octenoyl-CoA |