Values CatLog read from this paper
Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 and its absence in cytochrome P450 17A2
PMID 25533464doi:10.1074/jbc.m114.627265Open in Browse
The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.
CatLog read 6 records (18 values) from this paper: cytochrome P450 17A1 (zebrafish P450 17A1), cytochrome P450 17A2 (zebrafish P450 17A2) from Danio rerio.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cytochrome P450 17A1 (zebrafish P450 17A1) | Danio rerio | 17alpha-hydroxypregnenolone | 0.0055 | 0.0085 | 0.65 | pH 7.4, 37 °C | Open record: cytochrome P450 17A1 (zebrafish P450 17A1), 17alpha-hydroxypregnenolone |
| cytochrome P450 17A1 (zebrafish P450 17A1) | Danio rerio | 17alpha-hydroxyprogesterone | 0.02 | 0.0011 | 18 | pH 7.4, 37 °C | Open record: cytochrome P450 17A1 (zebrafish P450 17A1), 17alpha-hydroxyprogesterone |
| cytochrome P450 17A1 (zebrafish P450 17A1) | Danio rerio | pregnenolone | 0.033 | 0.002 | 17 | pH 7.4, 37 °C | Open record: cytochrome P450 17A1 (zebrafish P450 17A1), pregnenolone |
| cytochrome P450 17A1 (zebrafish P450 17A1) | Danio rerio | progesterone | 0.097 | 0.0017 | 57 | pH 7.4, 37 °C | Open record: cytochrome P450 17A1 (zebrafish P450 17A1), progesterone |
| cytochrome P450 17A2 (zebrafish P450 17A2) | Danio rerio | pregnenolone | 0.85 | 0.0093 | 92 | pH 7.4, 37 °C | Open record: cytochrome P450 17A2 (zebrafish P450 17A2), pregnenolone |
| cytochrome P450 17A2 (zebrafish P450 17A2) | Danio rerio | progesterone | 1.58 | 0.03 | 53 | pH 7.4, 37 °C | Open record: cytochrome P450 17A2 (zebrafish P450 17A2), progesterone |