CatLogenzyme kinetics catalog

Values CatLog read from this paper

Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme

PMID 10913258doi:10.1021/bi9928905Open in Browse

The paper itself is not on this site: read it at the publisher. This page lists only the values CatLog read from it.

CatLog read 66 records (127 values) from this paper: angiotensin I-converting enzyme (ACE) from Homo sapiens.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks. CatLog calculated the 61 kcat/Km values marked “calc.” from kcat and Km; no printed kcat/Km was read for those records.

EC 3.4.15.1

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)Conditions
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine——900pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-N-(2,4-dinitrophenyl)ethylenediamine——100pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.30.00132.5 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine10.40.00138.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine19 × 10⁻⁴1.1 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine1.89 × 10⁻⁴2.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminein the text——1.3 × 10³pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineFigure 32.20.00161.4 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine8.70.00155.8 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine4.20.00143.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine0.97 × 10⁻⁴1.3 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.00111.8 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.20.00161.4 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.70.00211.8 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine10.10.00263.9 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.0025800 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH210.40.0045.3 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH79.90.0117.3 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH230.90.01481.56 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OH44.20.0172.6 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine——70pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH820.01028.0 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH36.30.01542.36 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH246.30.00514.8 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH62.50.01115.63 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.0021.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine50.00143.6 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine1.40.00141.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine3.30.00331.0 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine4.20.006700 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine2.90.00241.2 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine1.40.00111.3 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine2.40.003800 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.39 × 10⁻⁴330 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine4.80.00341.4 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine12.60.00373.4 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.80.0021380 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH69.20.00272.6 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH310.02481.3 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH13.70.0229598 calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OH0.10.0323.1 calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH0.20.007427 calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH0.060.06090.99 calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH58.80.00471.3 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH70.015470 calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine1.20.0011.2 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine3.40.00181.9 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine0.90.0014640 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine3.80.005760 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.70.003900 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine2.60.00141.9 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine17 × 10⁻⁴1.4 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine1.30.003430 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine16 × 10⁻⁴1.7 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.40.003800 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.80.00241.6 × 10³ calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine1.60.0023700 calc.pH 8, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH54.90.00341.6 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH101.70.01875.44 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH167.80.01441.17 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OHin the text——1.1 × 10³pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OHFigure 524.60.0221.1 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH13.90.00314.5 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH18.70.01571.19 × 10³ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH85.60.0051.7 × 10⁴ calc.pH 7, 37 °COpen
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH28.90.00515.7 × 10³ calc.pH 7, 37 °COpen