CatLogenzyme kinetics catalog

EC 3.4.15.1: peptidyl-dipeptidase A

HydrolasesOpen in Browse

CatLog read 182 records for EC 3.4.15.1 from 11 papers, for 5 organisms. Names in these papers: angiotensin I-converting enzyme (ACE), h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme), ANCE (Drosophila angiotensin-converting enzyme), angiotensin I-converting enzyme (endothelial ACE, kininase II) and 13 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 40 records for EC 3.4.15.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.15.1 in Browse.

Papers

PaperOrganismsRecords
Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzymeHomo sapiens66
Characterization of four substrates emphasizes kinetic similarity between insect and human C-domain angiotensin-converting enzymeHomo sapiens, Locusta migratoria22
Structural diversity of angiotensin-converting enzymeDrosophila melanogaster18
Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activityHomo sapiens16
The two homologous domains of human angiotensin I-converting enzyme are both catalytically activeHomo sapiens12
Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzymeBos taurus11
Deglycosylation, processing and crystallization of human testis angiotensin-converting enzymeHomo sapiens9
The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance--distinct enzymic characteristics and alternative expression during pupal developmentDrosophila melanogaster8
Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and…Homo sapiens7
Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic propertiesOryctolagus cuniculus7
Drosophila melanogaster angiotensin I-converting enzyme expressed in Pichia pastoris resembles the C domain of the mammalian homologue and does not require glycosylation for secretion and enzymic…Drosophila melanogaster6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
Acer (Drosophila ACE-related)Drosophila melanogaster[Leu5]enkephalin (Tyr-Gly-Gly-Phe-Leu)—0.0406430pH 7.2, 37 °CPMID 9839949Open
Acer (Drosophila ACE-related)Drosophila melanogaster[Leu5]enkephalinamide (Tyr-Gly-Gly-Phe-Leu-NH2)—0.94942pH 7.2, 37 °CPMID 9839949Open
Acer (Drosophila ACE-related)Drosophila melanogasterbenzoylglycyl-histidyl-leucine (hippuryl-His-Leu)—1.215pH 8.3, 37 °CPMID 9839949Open
Acer (Drosophila ACE-related)Drosophila melanogasterhippuryl-histidyl-leucinamide (Hip-His-Leu-NH2)—4.350.86pH 8.3, 37 °CPMID 9839949Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogaster[Thr6]bradykinin0.60.00567110pH 8, 35 °CPMID 16403023Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogaster[Tyr8]bradykinin1.170.0113100pH 8, 35 °CPMID 16403023Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogasterAbz-YRK(Dnp)P—0.0046—pH 8, 20 °CPMID 16403023Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogasterangiotensin I0.011.580.0063 calc.pH 8, 35 °CPMID 16403023Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogasterbradykinin0.540.0048890pH 8, 35 °CPMID 16403023Open
ACER (Drosophila angiotensin-converting enzyme-related)Drosophila melanogasterIle-Ser-bradykinin0.170.0055430pH 8, 35 °CPMID 16403023Open
Ance (Drosophila angiotensin I-converting enzyme)Drosophila melanogaster[Leu5]enkephalin (Tyr-Gly-Gly-Phe-Leu)—0.3717170pH 7.2, 37 °CPMID 9839949Open
Ance (Drosophila angiotensin I-converting enzyme)Drosophila melanogaster[Leu5]enkephalinamide (Tyr-Gly-Gly-Phe-Leu-NH2)—1.8842pH 7.2, 37 °CPMID 9839949Open
Ance (Drosophila angiotensin I-converting enzyme)Drosophila melanogasterbenzoylglycyl-histidyl-leucine (hippuryl-His-Leu)—2.59279pH 8.3, 37 °CPMID 9839949Open
Ance (Drosophila angiotensin I-converting enzyme)Drosophila melanogasterhippuryl-histidyl-leucinamide (Hip-His-Leu-NH2)—10.2619pH 8.3, 37 °CPMID 9839949Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogaster[Thr6]bradykinin0.247.3 × 10⁻⁵3.31 × 10³pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogaster[Tyr8]bradykinin2.415.8 × 10⁻⁴4.15 × 10³pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterAbz-YRK(Dnp)P—0.00664—pH 8, 20 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterangiotensin I0 mM NaCl6.842.72.53pH 7, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterangiotensin I100 mM NaCl6.830.828.33pH 7, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterangiotensin I0 mM NaCl11.061.238.99pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterangiotensin I100 mM NaCl10.781.0410.37pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterbradykinin1.092.7 × 10⁻⁴4.04 × 10³pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterIle-Ser-bradykinin1.13 × 10⁻⁴3.66 × 10³pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterMKRSRGPSPRR—3.7 × 10⁻⁴—pH 8, 20 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterMKRSRGPSPRR18.8——pH 8, 35 °CPMID 16403023Open
ANCE (Drosophila angiotensin-converting enzyme)Drosophila melanogasterMKRSRGPSPRR——5.081 × 10⁴pH 8PMID 16403023Open
angiotensin I-converting enzyme (ACE)Homo sapiens2-furanacryloyl-Phe-Gly-Gly3200.1741.8 × 10³ calc.pH 7.5, 25 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapiensangiotensin I400.0162.5 × 10³ calc.pH 7.5, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapiensangiotensin Inative enzyme purified from human kidney (renal microsomes)400.0182.2 × 10³ calc.pH 7.5, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapienshippuryl-His-LeuTable II4081.54265 calc.pH 8.3, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapienshippuryl-His-Leunative enzyme purified from human kidney (renal microsomes)4141.61257 calc.pH 8.3, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapienshippuryl-His-LeuTable III3601.54230 calc.pH 8.3, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine——900pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-N-(2,4-dinitrophenyl)ethylenediamine——100pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.30.00132.5 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine10.40.00138.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine19 × 10⁻⁴1.1 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine1.89 × 10⁻⁴2.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminein the text——1.3 × 10³pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineFigure 32.20.00161.4 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine8.70.00155.8 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine4.20.00143.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine0.97 × 10⁻⁴1.3 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.00111.8 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.20.00161.4 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.70.00211.8 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine10.10.00263.9 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.0025800 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH210.40.0045.3 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH79.90.0117.3 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH230.90.01481.56 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OH44.20.0172.6 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine——70pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH820.01028.0 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH36.30.01542.36 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH246.30.00514.8 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH62.50.01115.63 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine20.0021.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine50.00143.6 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine1.40.00141.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine3.30.00331.0 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine4.20.006700 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine2.90.00241.2 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine1.40.00111.3 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine2.40.003800 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.39 × 10⁻⁴330 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine4.80.00341.4 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine12.60.00373.4 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.80.0021380 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH69.20.00272.6 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH310.02481.3 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH13.70.0229598 calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OH0.10.0323.1 calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH0.20.007427 calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH0.060.06090.99 calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH58.80.00471.3 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)C-domain (full-length ACE, N-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH70.015470 calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine1.20.0011.2 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine3.40.00181.9 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine0.90.0014640 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine3.80.005760 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.70.003900 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine2.60.00141.9 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine17 × 10⁻⁴1.4 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine1.30.003430 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine16 × 10⁻⁴1.7 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine2.40.003800 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine3.80.00241.6 × 10³ calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine1.60.0023700 calc.pH 8, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Arg-Lys(2,4-dinitrophenyl)-Pro-OH54.90.00341.6 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Phe-Asp-Lys(2,4-dinitrophenyl)-Pro-OH101.70.01875.44 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Arg-Lys(2,4-dinitrophenyl)-Pro-OH167.80.01441.17 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OHin the text——1.1 × 10³pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Ser-Asp-Lys(2,4-dinitrophenyl)-Pro-OHFigure 524.60.0221.1 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH13.90.00314.5 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Thr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH18.70.01571.19 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Arg-Lys(2,4-dinitrophenyl)-Pro-OH85.60.0051.7 × 10⁴ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)N-domain (full-length ACE, C-domain site inactivated: two zinc-binding His to Lys)Homo sapienso-aminobenzoyl-Tyr-Asp-Lys(2,4-dinitrophenyl)-Pro-OH28.90.00515.7 × 10³ calc.pH 7, 37 °CPMID 10913258Open
angiotensin I-converting enzyme (ACE)variant ΔCOOHHomo sapienshippuryl-His-Leu3581.59225 calc.pH 8.3, 37 °CPMID 1848554Open
angiotensin I-converting enzyme (AnCE)Drosophila melanogasterangiotensin I17.90.0335530pH 7.5, 37 °CPMID 8761461Open
angiotensin I-converting enzyme (AnCE)Drosophila melanogasterhippuryl-His-Leu (benzoyl-Gly-His-Leu)1551.7490pH 8.3PMID 8761461Open
angiotensin I-converting enzyme (AnCE)Drosophila melanogasterN-acetyl-Ser-Asp-Lys-Pro1.20.053420pH 7, 37 °CPMID 8761461Open
angiotensin I-converting enzyme (AnCE)variant N53Q/N196Q/N311QDrosophila melanogasterangiotensin I16.20.0691190pH 7.5, 37 °CPMID 8761461Open
angiotensin I-converting enzyme (AnCE)variant N53Q/N196Q/N311QDrosophila melanogasterhippuryl-His-Leu (benzoyl-Gly-His-Leu)1411.091130pH 8.3PMID 8761461Open
angiotensin I-converting enzyme (AnCE)variant N53Q/N196Q/N311QDrosophila melanogasterN-acetyl-Ser-Asp-Lys-Pro0.70.044620pH 7, 37 °CPMID 8761461Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)C fragmentHomo sapiensangiotensin I—0.016—pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)C fragmentHomo sapienshippuryl-L-histidyl-L-leucine—2—pH 8.3, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)N fragmentHomo sapiensangiotensin I—0.016—pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)N fragmentHomo sapienshippuryl-L-histidyl-L-leucine—1.98—pH 8.3, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant E362DHomo sapiensangiotensin I350.0181.9 × 10³ calc.pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant E362DHomo sapienshippuryl-L-histidyl-L-leucine3591.59226 calc.pH 8.3, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant E960DHomo sapiensangiotensin I—0.018—pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant E960DHomo sapienshippuryl-L-histidyl-L-leucine40220 calc.pH 8.3, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant H361K/H365KHomo sapiensangiotensin I340.0181.9 × 10³ calc.pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant H361K/H365KHomo sapienshippuryl-L-histidyl-L-leucine3641.59229 calc.pH 8.3, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant H959K/H963KHomo sapiensangiotensin I110.015730 calc.pH 7.5, 37 °CPMID 1851160Open
angiotensin I-converting enzyme (endothelial ACE, kininase II)variant H959K/H963KHomo sapienshippuryl-L-histidyl-L-leucine40220 calc.pH 8.3, 37 °CPMID 1851160Open
angiotensin-converting enzyme N-domainBos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-lysine350.14250 calc.pH 7.5, 25 °CPMID 12935891Open
angiotensin-converting enzyme N-domainBos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-proline80.0081.0 × 10³ calc.pH 7.5, 25 °CPMID 12935891Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln—0.0753—pH 7PMID 12135492Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile—0.0622—pH 7PMID 12135492Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu—0.0069—pH 7PMID 12135492Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu-Ser-Asp—0.2314—pH 7PMID 12135492Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensLeu-Glu-Gln-Ile-Tyr-His-Leu—0.0157—pH 7PMID 12135492Open
C-domain of angiotensin converting enzyme (cACE)Homo sapiensSer-Leu-Lys-Pro-Ser-Asn-Trp-Leu-Thr-Pro-Ser-Glu—0.108—pH 7PMID 12135492Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)Homo sapiens[Arg10]angiotensin I4600.0441.1 × 10⁴pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)Homo sapiens[Phe9,Arg10]angiotensin I1.4 × 10³0.0111.2 × 10⁵pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)Homo sapiens[Phe9]angiotensin I5500.0321.7 × 10⁴pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)Homo sapiensangiotensin I520.0521 × 10³pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087AHomo sapiens[Arg10]angiotensin I——57pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087AHomo sapiens[Phe9,Arg10]angiotensin I6.50.025260pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087AHomo sapiens[Phe9]angiotensin I——26pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098QHomo sapiens[Arg10]angiotensin I1000.22470pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098QHomo sapiens[Phe9,Arg10]angiotensin I1.7 × 10³0.028.6 × 10⁴pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098QHomo sapiens[Phe9]angiotensin I1.5 × 10³0.0423.7 × 10⁴pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098QHomo sapiensangiotensin I600.1600pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096FHomo sapiens[Arg10]angiotensin I570.0461.3 × 10³pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096FHomo sapiens[Phe9,Arg10]angiotensin I2200.0141.7 × 10⁴pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096FHomo sapiens[Phe9]angiotensin I1100.0561.9 × 10³pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096FHomo sapiensangiotensin I——18pH 7.5, 37 °CPMID 15615692Open
h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F/K1087AHomo sapiens[Phe9,Arg10]angiotensin I——17pH 7.5, 37 °CPMID 15615692Open
N-domain of angiotensin converting enzyme (nACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile—0.5237—pH 7PMID 12135492Open
N-domain of angiotensin converting enzyme (nACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu—0.1505—pH 7PMID 12135492Open
N-domain of angiotensin converting enzyme (nACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu-Ser-Asp—0.6738—pH 7PMID 12135492Open
N-domain of angiotensin converting enzyme (nACE)Homo sapiensLeu-Glu-Gln-Ile-Tyr-His-Leu—0.1592—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln—0.0905—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile—0.0815—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu—0.017—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu-Ser-Asp—0.1367—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensLeu-Glu-Gln-Ile-Tyr-His-Leu—0.0347—pH 7PMID 12135492Open
somatic angiotensin converting enzyme (sACE)Homo sapiensSer-Leu-Lys-Pro-Ser-Asn-Trp-Leu-Thr-Pro-Ser-Glu—0.3117—pH 7PMID 12135492Open
somatic angiotensin-converting enzyme (somatic ACE)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-lysine540.15360 calc.pH 7.5, 25 °CPMID 12935891Open
somatic angiotensin-converting enzyme (somatic ACE)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-proline300.0083.8 × 10³ calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaAsn-Lys-Leu-Lys-Pro-Ser-Gln—0.1126—pH 7PMID 12135492Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile—0.1472—pH 7PMID 12135492Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu—0.0027—pH 7PMID 12135492Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaAsn-Lys-Leu-Lys-Pro-Ser-Gln-Trp-Ile-Ser-Leu-Ser-Asp—0.459—pH 7PMID 12135492Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaLeu-Glu-Gln-Ile-Tyr-His-Leu—0.4125—pH 7PMID 12135492Open
testicular angiotensin converting enzyme (Lom testes ACE)Locusta migratoriaSer-Leu-Lys-Pro-Ser-Asn-Trp-Leu-Thr-Pro-Ser-Glu—0.2338—pH 7PMID 12135492Open
testicular angiotensin I-converting enzyme (tACE)Homo sapienshippuryl-L-histidyl-L-leucine1962.769pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g1Homo sapienshippuryl-L-histidyl-L-leucine1281.679pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g12Homo sapienshippuryl-L-histidyl-L-leucine1952.194pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g123Homo sapienshippuryl-L-histidyl-L-leucine2102.971pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g1234Homo sapienshippuryl-L-histidyl-L-leucine851.556pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g13Homo sapienshippuryl-L-histidyl-L-leucine1702.763pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36-g3Homo sapienshippuryl-L-histidyl-L-leucine1152.545pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36NJHomo sapienshippuryl-L-histidyl-L-leucinepresence of 1.5 mM NB-DNJ (glucosidase-I inhibitor)2532.699pH 8.3PMID 12542396Open
testicular angiotensin I-converting enzyme (tACE)variant tACEΔ36NJHomo sapienshippuryl-L-histidyl-L-leucineabsence of NB-DNJ3104.176pH 8.3PMID 12542396Open
testicular angiotensin-converting enzyme (ACET)Oryctolagus cuniculusangiotensin I39.5——pH 7.5, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)Oryctolagus cuniculushippuryl-L-histidyl-L-leucine1360.6227pH 8.3, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)variant K154EOryctolagus cuniculusangiotensin I42——pH 7.5, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)variant K154EOryctolagus cuniculushippuryl-L-histidyl-L-leucine1480.7211pH 8.3, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)variant K154E/Y236FOryctolagus cuniculushippuryl-L-histidyl-L-leucine73.71.9pH 8.3, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)variant Y236FOryctolagus cuniculusangiotensin I34——pH 7.5, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (ACET)variant Y236FOryctolagus cuniculushippuryl-L-histidyl-L-leucine1260.6210 calc.pH 8.3, 37 °CPMID 7902354Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-glycyl-glycine2600.5520 calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-alanine1780.053.6 × 10³ calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-lysine850.17500 calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-alanyl-L-proline450.0059.0 × 10³ calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-(3-[2-furyl]acryloyl)-L-phenylalanyl-L-phenylalanyl-L-arginine760.12630 calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-benzoyl-glycyl-L-histidyl-L-leucine120.620 calc.pH 7.5, 25 °CPMID 12935891Open
testicular angiotensin-converting enzyme (testicular ACE, C-domain)Bos taurusN-carbobenzoxy-L-phenylalanyl-L-histidyl-L-leucine190.13150 calc.pH 7.5, 25 °CPMID 12935891Open