Values CatLog read from this paper
Molecular basis of exopeptidase activity in the C-terminal domain of human angiotensin I-converting enzyme: insights into the origins of its exopeptidase activity
PMID 15615692doi:10.1074/jbc.m412638200Open in Browse
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CatLog read 16 records (40 values) from this paper: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) | Homo sapiens | [Arg10]angiotensin I | 460 | 0.044 | 1.1 × 10⁴ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme), [Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) | Homo sapiens | [Phe9,Arg10]angiotensin I | 1.4 × 10³ | 0.011 | 1.2 × 10⁵ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme), [Phe9,Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) | Homo sapiens | [Phe9]angiotensin I | 550 | 0.032 | 1.7 × 10⁴ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme), [Phe9]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) | Homo sapiens | angiotensin I | 52 | 0.052 | 1 × 10³ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme), angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087A | Homo sapiens | [Arg10]angiotensin I | — | — | 57 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant K1087A, [Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087A | Homo sapiens | [Phe9,Arg10]angiotensin I | 6.5 | 0.025 | 260 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant K1087A, [Phe9,Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant K1087A | Homo sapiens | [Phe9]angiotensin I | — | — | 26 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant K1087A, [Phe9]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098Q | Homo sapiens | [Arg10]angiotensin I | 100 | 0.22 | 470 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant R1098Q, [Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098Q | Homo sapiens | [Phe9,Arg10]angiotensin I | 1.7 × 10³ | 0.02 | 8.6 × 10⁴ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant R1098Q, [Phe9,Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098Q | Homo sapiens | [Phe9]angiotensin I | 1.5 × 10³ | 0.042 | 3.7 × 10⁴ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant R1098Q, [Phe9]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant R1098Q | Homo sapiens | angiotensin I | 60 | 0.1 | 600 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant R1098Q, angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F | Homo sapiens | [Arg10]angiotensin I | 57 | 0.046 | 1.3 × 10³ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant Y1096F, [Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F | Homo sapiens | [Phe9,Arg10]angiotensin I | 220 | 0.014 | 1.7 × 10⁴ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant Y1096F, [Phe9,Arg10]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F | Homo sapiens | [Phe9]angiotensin I | 110 | 0.056 | 1.9 × 10³ | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant Y1096F, [Phe9]angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F | Homo sapiens | angiotensin I | — | — | 18 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant Y1096F, angiotensin I |
| h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme)variant Y1096F/K1087A | Homo sapiens | [Phe9,Arg10]angiotensin I | — | — | 17 | pH 7.5, 37 °C | Open record: h-ACE C-domain (C-terminal catalytic domain of human angiotensin I-converting enzyme) variant Y1096F/K1087A, [Phe9,Arg10]angiotensin I |