Values CatLog read from this paper
H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia
PMID 19261609doi:10.1074/jbc.m808026200Open in Browse
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CatLog read 7 records (15 values) from this paper: cystathionine γ-lyase (CSE), polymorphic variant S403 from Homo sapiens.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units. Values are in CatLog's units; each record opens in Browse with the line the paper prints and the checks.
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Open record |
|---|---|---|---|---|---|---|---|
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-cystathionine | 2.3 | 0.28 | 8.2 | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-cystathionine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-cysteinereaction 2; α,β-elimination of cysteine | 0.31 | 3.7 | 0.08 | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-cysteine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-cysteinereaction 2; α,β-elimination of cysteine; 0.4 mM lead acetate | 0.47 | 1.7 | 0.27 | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-cysteine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-cysteinereaction 3; 0.4 mM lead acetate | 0.85 | — | — | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-cysteine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-homocysteinereaction 4; α,γ-elimination of homocysteine | 0.92 | 2.7 | 0.35 | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-homocysteine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-homocysteinereaction 5; 0.4 mM lead acetate | 4.9 | — | — | pH 7.4, 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-homocysteine |
| cystathionine γ-lyase (CSE), polymorphic variant S403 | Homo sapiens | L-homocysteine | 0.15 | — | — | 37 °C | Open record: cystathionine γ-lyase (CSE), polymorphic variant S403, L-homocysteine |